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Q9PL92 (RIR2_CHLMU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase subunit beta

EC=1.17.4.1
Alternative name(s):
Ribonucleotide reductase small subunit
Gene names
Name:nrdB
Ordered Locus Names:TC_0215
OrganismChlamydia muridarum (strain MoPn / Nigg) [Complete proteome] [HAMAP]
Taxonomic identifier243161 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Protein attributes

Sequence length346 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity.

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.

Cofactor

Binds 2 iron ions per subunit By similarity.

Pathway

Genetic information processing; DNA replication.

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase small chain family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 346346Ribonucleoside-diphosphate reductase subunit beta
PRO_0000190473

Sites

Active site1291 By similarity
Metal binding891Iron 1 By similarity
Metal binding1201Iron 1 By similarity
Metal binding1201Iron 2 By similarity
Metal binding1231Iron 1 By similarity
Metal binding1931Iron 2 By similarity
Metal binding2271Iron 2 By similarity
Metal binding2301Iron 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PL92 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: C5AF2C3372FBDA57

FASTA34640,488
        10         20         30         40         50         60 
MQADILDGKQ KRVNLNSKRL VNCNQVDVNQ LVPIKYKWAW EHYLNGCANN WLPTEISMGK 

        70         80         90        100        110        120 
DIELWKSNVL SEDERRVILL NLGFFSTAES LVGNNIVLAI FKHVTNPEAR QYLLRQAFEE 

       130        140        150        160        170        180 
AVHTHTFLYI CESLGLDEKE IFNAYNERAS IKAKDDFQME ITGKVLDPNF RTDSVEGLQE 

       190        200        210        220        230        240 
FIKNLVGYYI IMEGIFFYSG FVMILSFHRQ NKMVGIGEQY QYILRDETIH LNFGVDLING 

       250        260        270        280        290        300 
IKEENPEIWT TELQQEIIEM IQRAVDLEID YARDCLPRGI LGLRASMFID YVQHIADRRL 

       310        320        330        340 
ERIGLKPIYH TKNPFPWMSE TIDLNKEKNF FETRVTEYQH AASLTW 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE002160 Genomic DNA. Translation: AAF39087.1.
PIRG81728.
RefSeqNP_296594.1. NC_002620.2.

3D structure databases

ProteinModelPortalQ9PL92.
SMRQ9PL92. Positions 2-318.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243161.TC0215.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF39087; AAF39087; TC_0215.
GeneID1246341.
KEGGcmu:TC_0215.
PATRIC20371812. VBIChlMur19118_0235.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0208.
KOK00526.
OMAACANHWM.
OrthoDBEOG6J48J7.
ProtClustDBPRK07209.

Enzyme and pathway databases

BioCycCMUR243161:GHYU-226-MONOMER.
UniPathwayUPA00326.

Family and domain databases

Gene3D1.10.620.20. 1 hit.
InterProIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR026023. RNR_bsu_prok.
IPR000358. RNR_small.
[Graphical view]
PANTHERPTHR23409. PTHR23409. 1 hit.
PfamPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
PIRSFPIRSF000355. NrdB. 1 hit.
SUPFAMSSF47240. SSF47240. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIR2_CHLMU
AccessionPrimary (citable) accession number: Q9PL92
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways