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Q9PL91

- TRMB_CHLMU

UniProt

Q9PL91 - TRMB_CHLMU

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Chlamydia muridarum (strain MoPn / Nigg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    • Comment

    Functioni

    Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

    Catalytic activityi

    S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei54 – 541S-adenosyl-L-methionineUniRule annotation
    Binding sitei79 – 791S-adenosyl-L-methionineUniRule annotation
    Binding sitei106 – 1061S-adenosyl-L-methionineUniRule annotation
    Active sitei129 – 1291By similarity
    Binding sitei129 – 1291S-adenosyl-L-methionineUniRule annotation
    Binding sitei133 – 1331SubstrateUniRule annotation
    Binding sitei165 – 1651SubstrateUniRule annotation

    GO - Molecular functioni

    1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciCMUR243161:GHYU-227-MONOMER.
    UniPathwayiUPA00989.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
    Alternative name(s):
    tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
    tRNA(m7G46)-methyltransferaseUniRule annotation
    Gene namesi
    Name:trmBUniRule annotation
    Ordered Locus Names:TC_0216
    OrganismiChlamydia muridarum (strain MoPn / Nigg)
    Taxonomic identifieri243161 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
    ProteomesiUP000000800: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 224224tRNA (guanine-N(7)-)-methyltransferasePRO_0000171315Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243161.TC0216.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9PL91.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0220.
    KOiK03439.
    OMAiIVELAMN.
    OrthoDBiEOG6K6VBC.

    Family and domain databases

    Gene3Di3.40.50.150. 1 hit.
    HAMAPiMF_01057. tRNA_methyltr_TrmB.
    InterProiIPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view]
    PfamiPF02390. Methyltransf_4. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 1 hit.
    PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9PL91-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKPQDLKLPY FWEDRCPKIE NHVFYVPSYY PKYEEFVMPS WQNLFANEGP    50
    VCCELCSGNG DWVVEQALKD TSINWIAVEK RFDRVRKIWS KMSNHKVNNL 100
    LIVCGEAQTF FTHYVTDASF QKIVVNFPDP WPKFRHRKHR LFQDVFVQDM 150
    VRVLVEGGQL TLVTDDHTYL TNSIQVMLNY LSPGMQDPYY VNVKDNYGGS 200
    WFENLWRSKG EKIFCTEFVK RVGI 224
    Length:224
    Mass (Da):26,516
    Last modified:October 1, 2000 - v1
    Checksum:i8DC9A831A7B8A700
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE002160 Genomic DNA. Translation: AAF39088.1.
    PIRiF81726.
    RefSeqiNP_296595.1. NC_002620.2.

    Genome annotation databases

    EnsemblBacteriaiAAF39088; AAF39088; TC_0216.
    GeneIDi1246342.
    KEGGicmu:TC_0216.
    PATRICi20371814. VBIChlMur19118_0236.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE002160 Genomic DNA. Translation: AAF39088.1 .
    PIRi F81726.
    RefSeqi NP_296595.1. NC_002620.2.

    3D structure databases

    ProteinModelPortali Q9PL91.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243161.TC0216.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAF39088 ; AAF39088 ; TC_0216 .
    GeneIDi 1246342.
    KEGGi cmu:TC_0216.
    PATRICi 20371814. VBIChlMur19118_0236.

    Phylogenomic databases

    eggNOGi COG0220.
    KOi K03439.
    OMAi IVELAMN.
    OrthoDBi EOG6K6VBC.

    Enzyme and pathway databases

    UniPathwayi UPA00989 .
    BioCyci CMUR243161:GHYU-227-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 1 hit.
    HAMAPi MF_01057. tRNA_methyltr_TrmB.
    InterProi IPR029063. SAM-dependent_MTases-like.
    IPR003358. tRNA_(Gua-N-7)_MeTrfase.
    [Graphical view ]
    Pfami PF02390. Methyltransf_4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 1 hit.
    PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MoPn / Nigg.

    Entry informationi

    Entry nameiTRMB_CHLMU
    AccessioniPrimary (citable) accession number: Q9PL91
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 2001
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3