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Q9PKP3

- PKN1_CHLMU

UniProt

Q9PKP3 - PKN1_CHLMU

Protein

Serine/threonine-protein kinase pkn1

Gene

pkn1

Organism
Chlamydia muridarum (strain MoPn / Nigg)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Together with the serine/threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth.

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei42 – 421ATPPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 279ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCMUR243161:GHYU-437-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein kinase pkn1 (EC:2.7.11.1)
    Gene namesi
    Name:pkn1
    Ordered Locus Names:TC_0422
    OrganismiChlamydia muridarum (strain MoPn / Nigg)
    Taxonomic identifieri243161 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
    ProteomesiUP000000800: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 614614Serine/threonine-protein kinase pkn1PRO_0000171187Add
    BLAST

    Post-translational modificationi

    Autophosphorylated on serine and threonine residues.By similarity

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi243161.TC0422.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9PKP3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini13 – 302290Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    OMAiIDKSQAN.
    OrthoDBiEOG622PMB.

    Family and domain databases

    Gene3Di3.90.1580.10. 1 hit.
    InterProiIPR016187. C-type_lectin_fold.
    IPR005532. FGE_dom.
    IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    [Graphical view]
    PfamiPF03781. FGE-sulfatase. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    SSF56436. SSF56436. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9PKP3-1 [UniParc]FASTAAdd to Basket

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    MEEQSTVEYW GDYKVIAELE QGLWSRDVLT EHRFIKKRYV LKILPSELSL    50
    SEDFMKVFQK VIVQLATIRH PSLVAIENVS QEKDRYFIVT EENSGTISLA 100
    KYLSGRKLSE EEIVYLIQQL CEVLELVHEI GLAHGQINLH SVHVSFINGV 150
    ANIYLPEVGF ASLLRERMFS SIMQKASMQE SVECIRDLLV FEAPEEKSTN 200
    HRATDAYSVG VLAYYLLVGA FPWGAFPKPS SCIPDSIYDW DSFILSCLQQ 250
    QQQARPKRLR DALKKKTLGE QLQSTIDHCR ESLRAMEVQE EVSEPIAPTS 300
    LIREGEKLFE GKEEQQAFVL VEAKSIDEAM VTTVDSEEVS ESGEGYVNPL 350
    QSLLAREPVV SRYVEIEREE VKPQPLSTEM VFIEGGDFSR GSRDGQRDEL 400
    PVHNITLPGF LLDIHPVTNE HFVRFLEFIG GEQDEHYNEL IRLKDSRIQR 450
    RSGRLIIEPG YAKHPVVGVT WYGASSYASW IGKRLPSEAE WEVAAAGGKL 500
    GMRYPTGEDV DKSKANFFSS DTTPVMSYPA NILGLYDMAG NIYEWCQDWY 550
    SYDFYENSAL EPDSPQGPPQ GVYRVLRGGC WKSLKEDLRC AHRHRNNPGA 600
    INSTYGFRCA KDVK 614
    Length:614
    Mass (Da):69,782
    Last modified:October 1, 2000 - v1
    Checksum:iA24D888E70258B75
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE002160 Genomic DNA. Translation: AAF39278.1.
    PIRiH81703.
    RefSeqiNP_296799.1. NC_002620.2.

    Genome annotation databases

    EnsemblBacteriaiAAF39278; AAF39278; TC_0422.
    GeneIDi1245775.
    KEGGicmu:TC_0422.
    PATRICi20372250. VBIChlMur19118_0447.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE002160 Genomic DNA. Translation: AAF39278.1 .
    PIRi H81703.
    RefSeqi NP_296799.1. NC_002620.2.

    3D structure databases

    ProteinModelPortali Q9PKP3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243161.TC0422.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAF39278 ; AAF39278 ; TC_0422 .
    GeneIDi 1245775.
    KEGGi cmu:TC_0422.
    PATRICi 20372250. VBIChlMur19118_0447.

    Phylogenomic databases

    eggNOGi COG0515.
    OMAi IDKSQAN.
    OrthoDBi EOG622PMB.

    Enzyme and pathway databases

    BioCyci CMUR243161:GHYU-437-MONOMER.

    Family and domain databases

    Gene3Di 3.90.1580.10. 1 hit.
    InterProi IPR016187. C-type_lectin_fold.
    IPR005532. FGE_dom.
    IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    [Graphical view ]
    Pfami PF03781. FGE-sulfatase. 1 hit.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    SSF56436. SSF56436. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MoPn / Nigg.

    Entry informationi

    Entry nameiPKN1_CHLMU
    AccessioniPrimary (citable) accession number: Q9PKP3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 9, 2004
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Caution

    Gln-136 is present instead of the conserved Asp which is expected to be an active site residue.Curated

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3