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Q9PKP3 (PKN1_CHLMU) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase pkn1

EC=2.7.11.1
Gene names
Name:pkn1
Ordered Locus Names:TC_0422
OrganismChlamydia muridarum (strain MoPn / Nigg) [Complete proteome] [HAMAP]
Taxonomic identifier243161 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Protein attributes

Sequence length614 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Together with the serine/threonine kinase PknD, may play a role in the specific interactions with host proteins during intracellular growth.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Post-translational modification

Autophosphorylated on serine and threonine residues By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Caution

Gln-136 is present instead of the conserved Asp which is expected to be an active site residue.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 614614Serine/threonine-protein kinase pkn1
PRO_0000171187

Regions

Domain13 – 302290Protein kinase
Nucleotide binding19 – 279ATP By similarity

Sites

Binding site421ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PKP3 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: A24D888E70258B75

FASTA61469,782
        10         20         30         40         50         60 
MEEQSTVEYW GDYKVIAELE QGLWSRDVLT EHRFIKKRYV LKILPSELSL SEDFMKVFQK 

        70         80         90        100        110        120 
VIVQLATIRH PSLVAIENVS QEKDRYFIVT EENSGTISLA KYLSGRKLSE EEIVYLIQQL 

       130        140        150        160        170        180 
CEVLELVHEI GLAHGQINLH SVHVSFINGV ANIYLPEVGF ASLLRERMFS SIMQKASMQE 

       190        200        210        220        230        240 
SVECIRDLLV FEAPEEKSTN HRATDAYSVG VLAYYLLVGA FPWGAFPKPS SCIPDSIYDW 

       250        260        270        280        290        300 
DSFILSCLQQ QQQARPKRLR DALKKKTLGE QLQSTIDHCR ESLRAMEVQE EVSEPIAPTS 

       310        320        330        340        350        360 
LIREGEKLFE GKEEQQAFVL VEAKSIDEAM VTTVDSEEVS ESGEGYVNPL QSLLAREPVV 

       370        380        390        400        410        420 
SRYVEIEREE VKPQPLSTEM VFIEGGDFSR GSRDGQRDEL PVHNITLPGF LLDIHPVTNE 

       430        440        450        460        470        480 
HFVRFLEFIG GEQDEHYNEL IRLKDSRIQR RSGRLIIEPG YAKHPVVGVT WYGASSYASW 

       490        500        510        520        530        540 
IGKRLPSEAE WEVAAAGGKL GMRYPTGEDV DKSKANFFSS DTTPVMSYPA NILGLYDMAG 

       550        560        570        580        590        600 
NIYEWCQDWY SYDFYENSAL EPDSPQGPPQ GVYRVLRGGC WKSLKEDLRC AHRHRNNPGA 

       610 
INSTYGFRCA KDVK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE002160 Genomic DNA. Translation: AAF39278.1.
PIRH81703.
RefSeqNP_296799.1. NC_002620.2.

3D structure databases

ProteinModelPortalQ9PKP3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243161.TC0422.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF39278; AAF39278; TC_0422.
GeneID1245775.
KEGGcmu:TC_0422.
PATRIC20372250. VBIChlMur19118_0447.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
OMASESEGRC.
OrthoDBEOG622PMB.
ProtClustDBCLSK871217.

Enzyme and pathway databases

BioCycCMUR243161:GHYU-437-MONOMER.

Family and domain databases

Gene3D3.90.1580.10. 1 hit.
InterProIPR016187. C-type_lectin_fold.
IPR005532. FGE_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
[Graphical view]
PfamPF03781. FGE-sulfatase. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
SSF56436. SSF56436. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKN1_CHLMU
AccessionPrimary (citable) accession number: Q9PKP3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: October 1, 2000
Last modified: December 11, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families