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Q9PKK8

- G6PD_CHLMU

UniProt

Q9PKK8 - G6PD_CHLMU

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Protein

Glucose-6-phosphate 1-dehydrogenase

Gene
zwf, TC_0457
Organism
Chlamydia muridarum (strain MoPn / Nigg)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone By similarity.UniRule annotation

Catalytic activityi

D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei57 – 571NADP By similarity
Binding sitei168 – 1681NADP By similarity
Binding sitei198 – 1981Substrate By similarity
Binding sitei202 – 2021Substrate By similarity
Binding sitei236 – 2361Substrate By similarity
Binding sitei255 – 2551Substrate By similarity
Active sitei260 – 2601Proton acceptor By similarity
Binding sitei356 – 3561Substrate By similarity

GO - Molecular functioni

  1. glucose-6-phosphate dehydrogenase activity Source: UniProtKB-HAMAP
  2. NADP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciCMUR243161:GHYU-474-MONOMER.
UniPathwayiUPA00115; UER00408.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate 1-dehydrogenase (EC:1.1.1.49)
Short name:
G6PD
Gene namesi
Name:zwf
Ordered Locus Names:TC_0457
OrganismiChlamydia muridarum (strain MoPn / Nigg)
Taxonomic identifieri243161 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000800: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 507507Glucose-6-phosphate 1-dehydrogenaseUniRule annotationPRO_0000068115Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243161.TC0457.

Structurei

3D structure databases

ProteinModelPortaliQ9PKK8.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0364.
KOiK00036.
OMAiCIDANIN.
OrthoDBiEOG61308Z.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00966. G6PD.
InterProiIPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR23429. PTHR23429. 1 hit.
PfamiPF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000110. G6PD. 1 hit.
PRINTSiPR00079. G6PDHDRGNASE.
TIGRFAMsiTIGR00871. zwf. 1 hit.
PROSITEiPS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PKK8-1 [UniParc]FASTAAdd to Basket

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MEEIKEMGPT LPACPPCVMV IFGATGDLTA RKLFPALYNL TKEGRLSENF    50
VCVGFARRPK SHEQFREEMR QAIQNFSHSS EIDIRVWESL EHRIFYHQAN 100
FSEAEGYSSL RSFLESVDQK YGTKGNRLFY LSTPPDYFQE IIRNLNRHQL 150
FYHEQGAQQP WSRLIIEKPF GVDLQTAQEL QQCIDANINE ESVYRIDHYL 200
GKETVQNILT IRFANTLFES CWNSQYIDHV QISVSESIGI GSRGNFFEKS 250
GMLRDMVQNH LMQLLCLLTM EPPSEFSSAE IKKEKIKILK KILPIREEDV 300
IRGQYGEGVV QGVSVSGYRE EENVDPNSLV ETYVALKLFI DNPRWKGVPF 350
YLQAGKRLPK RTTDIAVIFK KSSYDLFNSE NCPLCPLEND LLIIRIQPDE 400
GVALQFNCKV PGTNKLVRPV KMDFRYDSYF NTVTPEAYER LLCDCILGDR 450
TLFTSNEEVL ASWELFSPLL EQWSKIRPIF PNYIAGSLRP QGADELLSRD 500
GRAWRSY 507
Length:507
Mass (Da):58,548
Last modified:October 1, 2000 - v1
Checksum:iC66F3FE1562391A6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE002160 Genomic DNA. Translation: AAF73556.1.
RefSeqiNP_296834.1. NC_002620.2.

Genome annotation databases

EnsemblBacteriaiAAF73556; AAF73556; TC_0457.
GeneIDi1245812.
KEGGicmu:TC_0457.
PATRICi20372332. VBIChlMur19118_0486.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE002160 Genomic DNA. Translation: AAF73556.1 .
RefSeqi NP_296834.1. NC_002620.2.

3D structure databases

ProteinModelPortali Q9PKK8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243161.TC0457.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF73556 ; AAF73556 ; TC_0457 .
GeneIDi 1245812.
KEGGi cmu:TC_0457.
PATRICi 20372332. VBIChlMur19118_0486.

Phylogenomic databases

eggNOGi COG0364.
KOi K00036.
OMAi CIDANIN.
OrthoDBi EOG61308Z.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00408 .
BioCyci CMUR243161:GHYU-474-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00966. G6PD.
InterProi IPR001282. G6P_DH.
IPR019796. G6P_DH_AS.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR23429. PTHR23429. 1 hit.
Pfami PF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000110. G6PD. 1 hit.
PRINTSi PR00079. G6PDHDRGNASE.
TIGRFAMsi TIGR00871. zwf. 1 hit.
PROSITEi PS00069. G6P_DEHYDROGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MoPn / Nigg.

Entry informationi

Entry nameiG6PD_CHLMU
AccessioniPrimary (citable) accession number: Q9PKK8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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