Reviewed, UniProtKB/Swiss-Prot Q9PKK7 (6PGL_CHLMU)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6PGL
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	TC_0458

Organism

Chlamydia muridarum [Complete proteome] [HAMAP]

Taxonomic identifier

83560 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia

Protein attributes

Sequence length	256 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.
Sequence similarities	Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 256	256	6-phosphogluconolactonase		PRO_0000090091

Sequences

	Sequence		Length	Mass (Da)
	Q9PKK7-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 8ACC9D04059199B6	FASTA	256	28,921
	10 20 30 40 50 60 MATLISLNDA NRMLIAESQE DFLQIACYDW ISTANKAIQK RGAFYVALSG GKTPLQIFQE 70 80 90 100 110 120 IVKKRAAISD CSKIFVFWGD ERASEDTEAG SNYLKAMDIL KWLRIPDTQI FRMDTANPKG 130 140 150 160 170 180 DEIYENLIRE HVPDTIFDMV MLGVGEDGHT LSLFPGTAAL EEKDRLVVFN EVPQLQTRRM 190 200 210 220 230 240 TLTFPIVRQA RHLVAYIQGT AKQDLCHKLL HPLGRDTFPI ERVGTPLNPL QWVLSSDCCR 250 AADLADIPAE CKLEMF

References

[1]

"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MoPn / Nigg.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE002160 Genomic DNA. Translation: AAF73557.1.
RefSeq	NP_296835.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1245813.
GenomeReviews	Gene locus TC_0458 in contig AE002160_GR.
KEGG	cmu:TC0458.
TIGR	TC_0458.
Phylogenomic databases
HOGENOM	Q9PKK7.
OMA	GDDRMVP.
Enzyme and pathway databases
BioCyc	CMUR243161:TC_0458-MON.
BRENDA	3.1.1.31. 256349.
Family and domain databases
InterPro	IPR005900. 6-phosphogluconolactonase. [Graphical view]
PANTHER	PTHR11054. Phosphogluconlac. 1 hit.
TIGRFAMs	TIGR01198. pgl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

6PGL_CHLMU

Accession

Primary (citable) accession number: Q9PKK7

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	October 1, 2000
Last modified:	November 3, 2009
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)