Reviewed, UniProtKB/Swiss-Prot Q9PKH8 (ALF1_CHLMU)

Names and origin

Protein names

Recommended name:
    Probable fructose-bisphosphate aldolase class 1
    EC=4.1.2.13
Alternative name(s):
    Probable fructose-bisphosphate aldolase class I
      Short name=FBP aldolase

Gene names

Name:	fbaB
Ordered Locus Names:	TC_0487

Organism

Chlamydia muridarum [Complete proteome] [HAMAP]

Taxonomic identifier

83560 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. FbaB subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 349	349	Probable fructose-bisphosphate aldolase class 1		PRO_0000138941
Sites
	Active site	236	1	Schiff-base intermediate with dihydroxyacetone-P By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9PKH8-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: EFFC4F47708E2686	FASTA	349	38,226
	10 20 30 40 50 60 MTTILDLLGK DADYLLNHQC IIKKEALTLP SGDFVSRVFA ESDRNNRVLR SLQQMFDHGR 70 80 90 100 110 120 LGGSGYLSIL PVDQGVEHTA GASFAKNPMY FDPENIVRLA IESGCSAVAS SYGVLSILAR 130 140 150 160 170 180 RYAHKIPFLL KLNHNELLSY PTTYHQIFFS QVEDAYNMGA VAVGATVYFG SESSNEEIVS 190 200 210 220 230 240 VAKAFSRARE LGLATVLWCY LRNPHFTRNG VDYHTAADLT GQADHLGATL GADIVKQKLP 250 260 270 280 290 300 TLQEGFKTIN FSKTDDLVYS ELSSNHPIDL CRYQVLNSYC GKVGLINSGG PSSGQNDFTE 310 320 330 340 AAKTAVINKR AGGMGLILGR KAFQRPFSEG VQLLNLIQDI YLDPTISIS

References

[1]

"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MoPn / Nigg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE002160 Genomic DNA. Translation: AAF39333.1.
PIR	G81697.
RefSeq	NP_296864.1.
3D structure databases
SMR	Q9PKH8. Positions 49-344.
ModBase	Search...
Genome annotation databases
GeneID	1245845.
GenomeReviews	Gene locus TC_0487 in contig AE002160_GR.
KEGG	cmu:TC0487.
TIGR	TC_0487.
Phylogenomic databases
HOGENOM	HBG553580.
OMA	YESENPG.
PhylomeDB	Q9PKH8.
Enzyme and pathway databases
BioCyc	CMUR243161:TC_0487-MONOMER.
BRENDA	4.1.2.13. 256349.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALF1_CHLMU

Accession

Primary (citable) accession number: Q9PKH8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 2001
Last sequence update:	October 1, 2000
Last modified:	January 19, 2010
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)