Reviewed, UniProtKB/Swiss-Prot Q9PKE6 (PHSG_CHLMU)

Names and origin

Protein names

Recommended name:
    Glycogen phosphorylase
    EC=2.4.1.1

Gene names

Name:	glgP
Ordered Locus Names:	TC_0519

Organism

Chlamydia muridarum [Complete proteome] [HAMAP]

Taxonomic identifier

83560 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia

Protein attributes

Sequence length	813 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity.
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the glycogen phosphorylase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glycogen metabolism
Ligand	Pyridoxal phosphate
Molecular function	Glycosyltransferase Transferase
Technical term	Allosteric enzyme Complete proteome
Gene Ontology (GO)
Biological process	glycogen metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 813	813	Glycogen phosphorylase		PRO_0000188550
Amino acid modifications
	Modified residue	662	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9PKE6-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 921CD13E1624916D	FASTA	813	92,652
	10 20 30 40 50 60 MHFDRMKINV ESMKQAILER VYCGVVQTPQ SASTRDIFTA VAKTVSEWMA KGWLKTQSSY 70 80 90 100 110 120 YDNDVKRVYY ISMEFLLGRS LKSNLLNLGL LDLVNEALSD LGYDFDQLVE MEHDAGLGNG 130 140 150 160 170 180 GLGRLAACFL DSMATLGIPA YGYGLRYDYG IFDQQIENGY QVESPDEWLR YGNPWEICRG 190 200 210 220 230 240 EYLYPVHFYG KVKHSMDSRG RDVAELVDSQ EVLAMAYDVP VPGFNNDTVN SLRLWQAQSR 250 260 270 280 290 300 HGFEFSYFNH GNYIRAIEDI ALASNITRVL YPNDSISEGQ ELRLKQEYFL VSATIQDILR 310 320 330 340 350 360 RYTKTHLSLD KLSEKVSVQL NDTHPALGIA EMMHILVDRE ELDWDVAWDT TTKIFNYTNH 370 380 390 400 410 420 TILPEALERW SLDLFSKVLP RHLEIIYEIN ARWLKKVSQK YPGDDDKRRA LSIIEEGSSK 430 440 450 460 470 480 FINMANLAVI GTSKVNGVSS FHSQLIKNTL FKDFVEFFPD KFINVTNGIT PRRWLALSNK 490 500 510 520 530 540 RLSALLNRSI GTDYLTNLTH LNKVISLAED SGFREEWHKI KIQNKEDLSA RIYKELGVSV 550 560 570 580 590 600 NPQSIFDCHI KRIHEYKRQL MNILRVIYFY NEIRNGSTEI VPTTVIFGGK AAPGYAMAKL 610 620 630 640 650 660 IIKLINNVAH IVNNDPKAKD LLKVVFWPNY RVSLAEAIIP ATDLSEQIST AGMEASGTGN 670 680 690 700 710 720 MKFALNGALT IGTMDGANIE MAEHIGKEHM FIFGLLEEEI SALRNEYYPQ GICNANPKIQ 730 740 750 760 770 780 EILDMVLQAR LPEEDKDLFK PIVNRLLNEG DPFFVLADLE SYLDAHNRVA RLFTQPEEWT 790 800 810 KKSIYNVGGI GFFSSDRSIT DYASNIWNVS QSS

References

[1]

"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MoPn / Nigg.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE002160 Genomic DNA. Translation: AAF39361.1.
PIR	G81694.
RefSeq	NP_296896.1.
3D structure databases
HSSP	HSSP built from PDB template 2GPN based on UniProtKB P00489.
ModBase	Search...
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Genome annotation databases
GeneID	1245879.
GenomeReviews	Gene locus TC_0519 in contig AE002160_GR.
KEGG	cmu:TC0519.
TIGR	TC_0519.
Phylogenomic databases
HOGENOM	Q9PKE6.
OMA	RFNAGDH.
Enzyme and pathway databases
BioCyc	CMUR243161:TC_0519-MON.
BRENDA	2.4.1.1. 256349.
Family and domain databases
InterPro	IPR011833. Glycg_phsphrylas. IPR000811. Glyco_trans_35. [Graphical view]
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02093. P_ylase. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHSG_CHLMU

Accession

Primary (citable) accession number: Q9PKE6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 2001
Last sequence update:	October 1, 2000
Last modified:	November 3, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)