Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serine/threonine-protein kinase PknD

Gene

pknD

Organism
Chlamydia muridarum (strain MoPn / Nigg)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331ATPUniRule annotation
Active sitei138 – 1381Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. protein serine/threonine kinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCMUR243161:GHYU-595-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase PknDUniRule annotation (EC:2.7.11.1UniRule annotation)
Gene namesi
Name:pknDUniRule annotation
Ordered Locus Names:TC_0575
OrganismiChlamydia muridarum (strain MoPn / Nigg)
Taxonomic identifieri243161 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000800 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 934934Serine/threonine-protein kinase PknDPRO_0000171191Add
BLAST

Post-translational modificationi

Autophosphorylated on serine and threonine residues.UniRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ9PK92.

Interactioni

Protein-protein interaction databases

STRINGi243161.TC0575.

Structurei

3D structure databases

ProteinModelPortaliQ9PK92.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 296293Protein kinaseUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.UniRule annotation
Contains 1 protein kinase domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0515.
KOiK08884.
OMAiSIFHKIC.
OrthoDBiEOG6W45P7.

Family and domain databases

HAMAPiMF_01957. PknD_kinase.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PK92-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQRYELIRLI GRGGMGEVYL AHDKACSRRV ALKKIREDLS DNPLLRKRFL
60 70 80 90 100
REAKIAADLI HPGIVPVYSI CSDGESVYYT MPYIEGFSLK HLLKSVWQKE
110 120 130 140 150
ILSKELEEKT SVKAFLPIFD KICATVEYIH SKGVLHRDLK PDNILLGLFG
160 170 180 190 200
EVVIVDWGAA IFKHAKELQQ EKDEEGFSSY GQKNICYSSM TVPGKIVGTP
210 220 230 240 250
DYMAPESLLG AEASEKTDIY ALGLILYQML TLSFPYRRKK GRKLPYEDSI
260 270 280 290 300
LSPIEMAPYR EIPPSLSQIA MKAIAVDPVQ RFSSVQELRK ALQPHLQGES
310 320 330 340 350
EWTTRDILST KDRKNWKYYE PILLSRYFPV LASSPAQWYN FMLSDMEVNS
360 370 380 390 400
SVRVECSVTK SSVQEGVGIF FPPSKEADKG EFYCGYGLWF SSQNNELSVS
410 420 430 440 450
LIKNGIEIQK ESQGIIPQQS RFAISIEKSN NKITVFVDQI LFILHIDYLP
460 470 480 490 500
SLGERIEIII QDLQGISNIT ILESIGALRV SCLAVPDAFL AEKLYDQAAR
510 520 530 540 550
FYRKIRDSFP GRKESYEAQF RLGVTLLTQI EEQGGDLMQA LSTFDLLHGS
560 570 580 590 600
TGAPLEYLGK ALVYQRNGSF VEEIRSLLLA LKRYPQHPEI PRLKDHLCFR
610 620 630 640 650
LYDSLHKHRS EALVFMLLIL WIAPEKIGLR EEERFLEFLH HRQQSTLFCR
660 670 680 690 700
IDKTPLQFKS SKMELFLSFW TGFTLFLPEL FQRARDLRDY QALIDIFYVV
710 720 730 740 750
CASGNKEVFS QFAEDLAIFV DEVVFPKSLH NQRGEELVLF VQGLAALQNR
760 770 780 790 800
EYRQAKEFIS AVPFALQLYA LDLFSLQAFI DEEVKVFSDF LQDIYNSASA
810 820 830 840 850
EDHKHVLVYM IQVSLWNQDL KQAYELLSKN FPQDKGLIEY SEAFVLWGCY
860 870 880 890 900
LALTGDRSAV KAHFSRCQFK YGRSALIGKC IDDDSLDYLE GLVWWEKKKT
910 920 930
LFQSYFLLRC LHAPKERYEV YRQAYISMEN SFFG
Length:934
Mass (Da):107,499
Last modified:October 1, 2000 - v1
Checksum:iF08AEFD10A47E05C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002160 Genomic DNA. Translation: AAF73573.1.
RefSeqiNP_296951.1. NC_002620.2.

Genome annotation databases

EnsemblBacteriaiAAF73573; AAF73573; TC_0575.
KEGGicmu:TC_0575.
PATRICi20372594. VBIChlMur19118_0613.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002160 Genomic DNA. Translation: AAF73573.1.
RefSeqiNP_296951.1. NC_002620.2.

3D structure databases

ProteinModelPortaliQ9PK92.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243161.TC0575.

Proteomic databases

PRIDEiQ9PK92.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF73573; AAF73573; TC_0575.
KEGGicmu:TC_0575.
PATRICi20372594. VBIChlMur19118_0613.

Phylogenomic databases

eggNOGiCOG0515.
KOiK08884.
OMAiSIFHKIC.
OrthoDBiEOG6W45P7.

Enzyme and pathway databases

BioCyciCMUR243161:GHYU-595-MONOMER.

Family and domain databases

HAMAPiMF_01957. PknD_kinase.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MoPn / Nigg.

Entry informationi

Entry nameiPKND_CHLMU
AccessioniPrimary (citable) accession number: Q9PK92
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: October 1, 2000
Last modified: April 1, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.