Q9PK67 (TRPF_CHLMU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	TC_0603

Organism

Chlamydia muridarum (strain MoPn / Nigg) [Complete proteome] [HAMAP]

Taxonomic identifier

243161 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Chlamydiae/Verrucomicrobia group › Chlamydiae › Chlamydiia › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia › Chlamydia muridarum

Protein attributes

Sequence length	208 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 208	208	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_0000154353

Sequences

	Sequence		Length	Mass (Da)
	Q9PK67 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 29F71CE4A8FAF959	FASTA	208	22,234
	10 20 30 40 50 60 MKVKICGVTH PDDAWEAAKA GADYVGMIFA KDSQRCVTKE TAKCIVEAIR DGGSEPVGVF 70 80 90 100 110 120 SEHSIGEIIA ISSATGITSI QLSGRNIDFK FSQLRELFSI FYVVSVYSNG QPSAAIPPMS 130 140 150 160 170 180 NTVTVIYDHI GGERGTPFDW RAFSPFQHDN WMLGGGVNPG NVGEAVRLLS PRGIDVSSGV 190 200 ERPGVLRKDV TLMQALIDSA KGVGNLTS

References

[1]

"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MoPn / Nigg.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE002160 Genomic DNA. Translation: AAF73577.1.
RefSeq	NP_296979.1. NC_002620.2.
3D structure databases
ProteinModelPortal	Q9PK67.
ModBase	Search...
Protein-protein interaction databases
STRING	243161.TC0603.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAF73577; AAF73577; TC_0603.
GeneID	1245965.
KEGG	cmu:TC0603.
PATRIC	20372658. VBIChlMur19118_0642.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
KO	K01817.
OMA	TILLDAF.
ProtClustDB	PRK01222.
Enzyme and pathway databases
BioCyc	CMUR243161:GHYU-595-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_CHLMU

Accession

Primary (citable) accession number: Q9PK67

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
Last sequence update:	October 1, 2000
Last modified:	May 1, 2013
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program