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Reviewed, UniProtKB/Swiss-Prot Q9PK61 (KPYK_CHLMU)

Last modified June 16, 2009. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Pyruvate kinase
      Short name=PK
    EC=2.7.1.40
Gene names
Name: pyk
Ordered Locus Names: TC_0609
OrganismChlamydia muridarum [Complete proteome] [HAMAP]
Taxonomic identifier83560 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia

Protein attributes

Sequence length481 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + pyruvate = ADP + phosphoenolpyruvate.

Cofactor

Magnesium.

Potassium.

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the pyruvate kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 481481Pyruvate kinase
PRO_0000112061

Sites

Active site2191 By similarity
Metal binding2211Magnesium By similarity
Metal binding2421Magnesium By similarity
Metal binding2431Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PK61-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 9222E5DAED557B51

FASTA48153,175
        10         20         30         40         50         60 
MIARTKIICT IGPATNTPEM LEKLLDAGMN VARLNFSHGT HESHGRTIAI LKELREKRQV 

        70         80         90        100        110        120 
PLAIMLDTKG PEIRLGQVES PIKVKPGDRL TLTSKEILGS KEAGVTLYPS CVFPFVRERA 

       130        140        150        160        170        180 
PVLIDDGYIQ AVVVNAQEHL IEIEFQNSGE IKSNKSLSIK DIDVALPFMT EKDITDLKFG 

       190        200        210        220        230        240 
VEQELDLIAA SFVRCNEDID SMRKVLENFG RPNMPIIAKI ENHLGVQNFQ EIAKASDGIM 

       250        260        270        280        290        300 
IARGDLGIEL SIVEVPALQK FMARVSRETG RFCITATQML ESMIRNPLPT RAEVSDVANA 

       310        320        330        340        350        360 
IHDGTSAVML SGETASGTYP IEAVKTMRSI IQETEKSFDY QAFFQLNDKN SALKVSPYLE 

       370        380        390        400        410        420 
AIGASGIQIA EKASAKAIIV YTQTGGSPMF LSKYRPYLPI IAVTPNRNVY YRLAVEWGVY 

       430        440        450        460        470        480 
PMLTSESNRT VWRHQACVYG VEKGILSNYD KILVFSRGAG MQDTNNLTLT TVNDVLSPSL 


E 

« Hide

Cross-references

Sequence databases

AE002160 Genomic DNA. Translation: AAF39440.1.
PIRF81684.
RefSeqNP_296985.1.

3D structure databases

HSSPHSSP built from PDB template 1E0T based on UniProtKB P14178.
ModBaseSearch...

Genome annotation databases

GeneID1245971.
GenomeReviewsGene locus TC_0609 in contig AE002160_GR.
KEGGcmu:TC0609.
TIGRTC_0609.

Phylogenomic databases

HOGENOMQ9PK61.
OMAQ9PK61. DSECAVK.

Enzyme and pathway databases

BioCycCMUR243161:TC_0609-MON.
BRENDA2.7.1.40. 256349.

Family and domain databases

InterProIPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase_cat.
IPR015794. Pyrv_Knase_a/b.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
[Graphical view]
Gene3DG3DSA:3.20.20.60. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
G3DSA:3.40.1380.20. Pyrv_Knase_a/b. 1 hit.
PANTHERPTHR11817. Pyruvate_kinase. 1 hit.
PfamPF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
[Graphical view]
PRINTSPR01050. PYRUVTKNASE.
ProDomPD001009. Pyruvate_kinase. 2 hits.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR01064. pyruv_kin. 1 hit.
PROSITEPS00110. PYRUVATE_KINASE. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameKPYK_CHLMU
AccessionPrimary (citable) accession number: Q9PK61
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: June 16, 2009
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents