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Q9PJZ1 (RISA_CHLMU) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Riboflavin synthase

Short name=RS
EC=2.5.1.9
Gene names
Name:ribE
Synonyms:ribC
Ordered Locus Names:TC_0685
OrganismChlamydia muridarum (strain MoPn / Nigg) [Complete proteome] [HAMAP]
Taxonomic identifier243161 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia

Protein attributes

Sequence length198 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil By similarity.

Catalytic activity

2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine.

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2.

Subunit structure

Homotrimer By similarity.

Sequence similarities

Contains 2 lumazine-binding repeats.

Ontologies

Keywords
   Biological processRiboflavin biosynthesis
   DomainRepeat
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processriboflavin biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionoxidoreductase activity

Inferred from electronic annotation. Source: InterPro

riboflavin synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 198198Riboflavin synthase
PRO_0000068163

Regions

Repeat1 – 9595Lumazine-binding 1
Repeat96 – 18893Lumazine-binding 2
Region4 – 63Substrate binding By similarity
Region46 – 483Substrate binding By similarity
Region60 – 656Substrate binding By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PJZ1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 8C6218EFBD94C318

FASTA19821,761
        10         20         30         40         50         60 
MFSGIIQEVA RVDLIHHYGD SMEIGIFARN LVDGVPGSSI AVDGICLTLV KREFELLFFD 

        70         80         90        100        110        120 
VTEETMACTT IKNYTVGSMV NLERSVRLGD EIGGHFVSGH VCGVGTIIAV EKSYMFFKAP 

       130        140        150        160        170        180 
TNLVPYVLEK GFIAIDGISL TIAQVRGDIF SVSVIPETRA RTSLGYKQVG SHVNMEPDMM 

       190 
TKMQVDTVMR FQAEKIGK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE002160 Genomic DNA. Translation: AAF39502.1.
PIRG81675.
RefSeqNP_297059.1. NC_002620.2.

3D structure databases

ProteinModelPortalQ9PJZ1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243161.TC0685.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF39502; AAF39502; TC_0685.
GeneID1246046.
KEGGcmu:TC_0685.
PATRIC20372826. VBIChlMur19118_0725.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0307.
KOK00793.
OMARIVAHQL.
OrthoDBEOG6VMTQH.
ProtClustDBPRK09289.

Enzyme and pathway databases

BioCycCMUR243161:GHYU-708-MONOMER.
UniPathwayUPA00275; UER00405.

Family and domain databases

Gene3D2.40.30.20. 2 hits.
InterProIPR023366. ATPase_asu-like.
IPR001783. Lumazine-bd.
IPR026017. Lumazine-bd_dom.
IPR017938. Riboflavin_synthase-like_b-brl.
[Graphical view]
PANTHERPTHR21098. PTHR21098. 1 hit.
PfamPF00677. Lum_binding. 2 hits.
[Graphical view]
PIRSFPIRSF000498. Riboflavin_syn_A. 1 hit.
SUPFAMSSF63380. SSF63380. 2 hits.
TIGRFAMsTIGR00187. ribE. 1 hit.
PROSITEPS51177. LUMAZINE_BIND. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRISA_CHLMU
AccessionPrimary (citable) accession number: Q9PJZ1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: October 1, 2000
Last modified: December 11, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways