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Q9PJF5

- SYW_CHLMU

UniProt

Q9PJF5 - SYW_CHLMU

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Protein

Tryptophan--tRNA ligase

Gene

trpS

Organism
Chlamydia muridarum (strain MoPn / Nigg)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei204 – 2041ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. tryptophan-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tryptophanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCMUR243161:GHYU-904-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan--tRNA ligase (EC:6.1.1.2)
Alternative name(s):
Tryptophanyl-tRNA synthetase
Short name:
TrpRS
Gene namesi
Name:trpS
Ordered Locus Names:TC_0874
OrganismiChlamydia muridarum (strain MoPn / Nigg)
Taxonomic identifieri243161 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000000800: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Tryptophan--tRNA ligasePRO_0000136618Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi243161.TC0874.

Structurei

3D structure databases

ProteinModelPortaliQ9PJF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi12 – 209"HIGH" region
Motifi201 – 2055"KMSKS" region

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0180.
KOiK01867.
OMAiGENFFPI.
OrthoDBiEOG686NJQ.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00140_B. Trp_tRNA_synth_B.
InterProiIPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view]
PANTHERiPTHR10055. PTHR10055. 1 hit.
PfamiPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSiPR01039. TRNASYNTHTRP.
TIGRFAMsiTIGR00233. trpS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9PJF5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKKRVLTGD RPTGKLHLGH WIGSIMNRLQ LQNDPRYDCF FIIADLHTLT
60 70 80 90 100
TKTRKEEVLH IDSHIYDVLA DWLSVGIDPE KSAIYLQSAI PEIYELNLLF
110 120 130 140 150
SMLTPLNHIM GIPSIKEMAR NASINEESLS HGLIGYPVLQ SADILLAKAH
160 170 180 190 200
LVPVGKDNEA HVELTRDIAK TFNRLYGSVF PEPDILQGEL TSLVGTNGQG
210 220 230 240 250
KMSKSANNAI YLSDDEKTVQ EKIRKMYTDP NRVHATTPGR VEGNPLFIYH
260 270 280 290 300
DLFNPHKEEV EEFKTRYRQG CIKDVEVKAR LAEEINLFLN PFREKRSEFV
310 320 330 340
AQPKILEEAL QKGTEKMRSV ARETMEEVHN NLGLSRKWRS ILASSK
Length:346
Mass (Da):39,412
Last modified:October 1, 2000 - v1
Checksum:i2EE5FAAFD0BDB95B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002160 Genomic DNA. Translation: AAF39670.1.
PIRiC81654.
RefSeqiNP_297247.1. NC_002620.2.

Genome annotation databases

EnsemblBacteriaiAAF39670; AAF39670; TC_0874.
GeneIDi1246242.
KEGGicmu:TC_0874.
PATRICi20373264. VBIChlMur19118_0936.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE002160 Genomic DNA. Translation: AAF39670.1 .
PIRi C81654.
RefSeqi NP_297247.1. NC_002620.2.

3D structure databases

ProteinModelPortali Q9PJF5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243161.TC0874.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAF39670 ; AAF39670 ; TC_0874 .
GeneIDi 1246242.
KEGGi cmu:TC_0874.
PATRICi 20373264. VBIChlMur19118_0936.

Phylogenomic databases

eggNOGi COG0180.
KOi K01867.
OMAi GENFFPI.
OrthoDBi EOG686NJQ.

Enzyme and pathway databases

BioCyci CMUR243161:GHYU-904-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_00140_B. Trp_tRNA_synth_B.
InterProi IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR024109. Trp-tRNA-ligase_bac-type.
[Graphical view ]
PANTHERi PTHR10055. PTHR10055. 1 hit.
Pfami PF00579. tRNA-synt_1b. 1 hit.
[Graphical view ]
PRINTSi PR01039. TRNASYNTHTRP.
TIGRFAMsi TIGR00233. trpS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MoPn / Nigg.

Entry informationi

Entry nameiSYW_CHLMU
AccessioniPrimary (citable) accession number: Q9PJF5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: October 29, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3