Reviewed, UniProtKB/Swiss-Prot Q9PJD4 (NTPA_CHLMU)

Names and origin

Protein names

Recommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase

Gene names

Ordered Locus Names:

TC_0895

Organism

Chlamydia muridarum [Complete proteome] [HAMAP]

Taxonomic identifier

83560 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia

Protein attributes

Sequence length	209 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.
Catalytic activity	NTP + H2O = NDP + phosphate. HAMAP MF_01405
Cofactor	Divalent cations By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the HAM1 NTPase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	nucleoside-triphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 209	209	Nucleoside-triphosphatase HAMAP MF_01405		PRO_0000178149

Sequences

	Sequence		Length	Mass (Da)
	Q9PJD4-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 4EC73447310682F4	FASTA	209	23,383
	10 20 30 40 50 60 MKILIASSHG YKVRETKAFL KKIGEFDIFS LVDYPSYTPP KETGETPEEN AIQKGVFAAQ 70 80 90 100 110 120 TFRCWTIADD SMLIIPALGG LPGKLSASFS GEHASDKDHR KKLLEEMLLL ENPIDRSAYF 130 140 150 160 170 180 ECCVVLVSPF GKIFKAHASC EGTIVFKERG SSGFGYDPLF SKHDYKQTYA ELPEEIKNQV 190 200 SHRAKALAKL QPYVEMAFAN HLLARNESL

References

[1]

"Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39." Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O., Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S., Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J., Gwinn M.L. , Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G., Salzberg S.L., Eisen J.A., Fraser C.M. Nucleic Acids Res. 28:1397-1406(2000) [PubMed: 10684935] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MoPn / Nigg.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE002160 Genomic DNA. Translation: AAF39689.1.
PIR	H81651.
RefSeq	NP_297268.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1246264.
GenomeReviews	Gene locus TC_0895 in contig AE002160_GR.
KEGG	cmu:TC0895.
TIGR	TC_0895.
Phylogenomic databases
HOGENOM	Q9PJD4.
OMA	Q9PJD4. VEMAFAN.
Enzyme and pathway databases
BioCyc	CMUR243161:TC_0895-MON.
BRENDA	3.6.1.15. 256349.
Family and domain databases
HAMAP	MF_01405. [Tree]
InterPro	IPR002637. Ham1p-like. [Graphical view]
PANTHER	PTHR11067. Ham1p_like. 1 hit.
Pfam	PF01725. Ham1p_like. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NTPA_CHLMU

Accession

Primary (citable) accession number: Q9PJD4

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2002
Last sequence update:	October 1, 2000
Last modified:	June 16, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)