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Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei74Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processDNA damage, DNA repair

Enzyme and pathway databases

BioCyciCJEJ192222:G1G1F-80-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ungUniRule annotation
Ordered Locus Names:Cj0086c
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000799 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001760771 – 231Uracil-DNA glycosylaseAdd BLAST231

Proteomic databases

PaxDbiQ9PJ40
PRIDEiQ9PJ40

Interactioni

Protein-protein interaction databases

IntActiQ9PJ40, 22 interactors
STRINGi192222.Cj0086c

Structurei

3D structure databases

ProteinModelPortaliQ9PJ40
SMRiQ9PJ40
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D5S Bacteria
COG0692 LUCA
HOGENOMiHOG000229528
KOiK03648
OMAiQANGLCF

Family and domain databases

CDDicd10027 UDG_F1, 1 hit
Gene3Di3.40.470.10, 1 hit
HAMAPiMF_00148 UDG, 1 hit
InterProiView protein in InterPro
IPR002043 UDG_fam1
IPR018085 Ura-DNA_Glyclase_AS
IPR005122 Uracil-DNA_glycosylase-like
IPR036895 Uracil-DNA_glycosylase-like_sf
PANTHERiPTHR11264 PTHR11264, 1 hit
PfamiView protein in Pfam
PF03167 UDG, 1 hit
SMARTiView protein in SMART
SM00986 UDG, 1 hit
SUPFAMiSSF52141 SSF52141, 1 hit
TIGRFAMsiTIGR00628 ung, 1 hit
PROSITEiView protein in PROSITE
PS00130 U_DNA_GLYCOSYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q9PJ40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEITINIDK IKINDDWKEF LRDEFQKKYF LEIKKQYLNA INQNIIIYPP
60 70 80 90 100
ANLIFNAFNL CPLKEIKIII LGQDPYHQPN QAMGLSFSVP KNVKIPPSLN
110 120 130 140 150
NIFKELQNDL NITPAKSGDL SSWAKQGVLL LNSILSVEAN KAASHSSWGW
160 170 180 190 200
QEFSDAIIHK LSNEKSGLVF MLWGNYAKNK EILIDNTKHL ILKAAHPSPL
210 220 230
ARTGFLGCKH FSKANEFLKK VGKIPIDWKI V
Length:231
Mass (Da):26,341
Last modified:October 1, 2000 - v1
Checksum:iC3514FCA0C38199A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL111168 Genomic DNA Translation: CAL34257.1
PIRiF81424
RefSeqiWP_002851931.1, NC_002163.1
YP_002343546.1, NC_002163.1

Genome annotation databases

EnsemblBacteriaiCAL34257; CAL34257; Cj0086c
GeneIDi904411
KEGGicje:Cj0086c
PATRICifig|192222.6.peg.84

Similar proteinsi

Entry informationi

Entry nameiUNG_CAMJE
AccessioniPrimary (citable) accession number: Q9PJ40
Secondary accession number(s): Q0PC51
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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