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Q9PJ21 (ATPA_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
ATP synthase subunit alpha
EC=3.6.3.14
Alternative name(s):
ATP synthase F1 sector subunit alpha
F-ATPase subunit alpha
Gene names
Name:atpA
Ordered Locus Names:Cj0105
OrganismCampylobacter jejuni
Taxonomic identifier197 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length501 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit By similarity. HAMAP MF_01346

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP MF_01346

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_01346.

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 501501ATP synthase subunit alpha HAMAP MF_01346
PRO_0000238226

Regions

Nucleotide binding169 – 1768ATP By similarity

Sites

Site3621Required for activity By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PJ21 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 4284341E63E209C3

FASTA50154,801
        10         20         30         40         50         60 
MKFKADEISS IIKERIENFD LNLEIEETGK IISVADGVAK VYGLKNIMAG EMVEFENGDK 

        70         80         90        100        110        120 
GMALNLEESS VGIVILGKGE GLKEGASVKR LKKLLKVPVG EALIGRVVNA LGEPIDAKGV 

       130        140        150        160        170        180 
INANEYRFVE EKAKGIMARK SVHEPLHTGI KAIDALVPIG RGQRELIIGD RQTGKTTVAV 

       190        200        210        220        230        240 
DTIISQRGQG VICIYVAIGQ KQSTVAQVVK RLEEHGAMEY TIVVNAGASD PAALQYLAPY 

       250        260        270        280        290        300 
TGVTMGEFFR DNAKHALIVY DDLSKHAVAY REMSLILRRP PGREAYPGDV FYLHSRLLER 

       310        320        330        340        350        360 
ASKLNDELGA GSLTALPIIE TQAGDVSAYI PTNVISITDG QIFLETDLFN SGIRPAINVG 

       370        380        390        400        410        420 
LSVSRVGGAA QIKATKQVSG TLRLDLAQYR ELQAFAQFAS DLDEASRKQL ERGQRMVELL 

       430        440        450        460        470        480 
KQPPYSPLSV EKQVVLIFAG TKGFLDDIAV SRIKEFEDGI YPFIEAKHPD IFEQIRSKKA 

       490        500 
LDSDLEEKLA KAINEFKANH L

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL111168 Genomic DNA. Translation: CAL34276.1.
PIRA81427.
RefSeqYP_002343565.1. NC_002163.1.

3D structure databases

ProteinModelPortalQ9PJ21.
SMRQ9PJ21. Positions 17-497.
ModBaseSearch...

Proteomic databases

PRIDEQ9PJ21.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID904435.
GenomeReviewsGene locus Cj0105 in contig AL111168_GR.
KEGGcje:Cj0105.
PATRIC20057137. VBICamJej33762_0103.

Phylogenomic databases

HOGENOMHBG565875.
OMAGSDRDIK.
PhylomeDBQ9PJ21.
ProtClustDBPRK09281.

Enzyme and pathway databases

BioCycCJEJ192222:CJ0105-MONOMER.

Family and domain databases

HAMAPMF_01346. ATP_synth_alpha_bact.
[Tree]
InterProIPR020003. ATPase_a/bsu_AS.
IPR005294. ATPase_F1-cplx_asu.
IPR018118. ATPase_F1/A1-cplx_a/bsu_N.
IPR023366. ATPase_F1/A1-cplx_a_su_N.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
[Graphical view]
Gene3DG3DSA:2.40.30.20. G3DSA:2.40.30.20. 1 hit.
KOK02111.
PANTHERPTHR15184:SF3. ATPase_F1_a. 1 hit.
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SUPFAMSSF47917. ATPase_a/b_C. 1 hit.
SSF50615. ATPase_a/b_N. 1 hit.
TIGRFAMsTIGR00962. AtpA. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATPA_CAMJE
AccessionPrimary (citable) accession number: Q9PJ21
Secondary accession number(s): Q0PC32
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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