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Q9PIM0 (CLPX_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP-dependent Clp protease ATP-binding subunit ClpX
Gene names
Name:clpX
Ordered Locus Names:Cj0275
OrganismCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168) [Reference proteome] [HAMAP]
Taxonomic identifier192222 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP By similarity. HAMAP-Rule MF_00175

Subunit structure

Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes By similarity.

Sequence similarities

Belongs to the ClpX chaperone family.

Ontologies

Keywords
   DomainZinc-finger
   LigandATP-binding
Metal-binding
Nucleotide-binding
Zinc
   Molecular functionChaperone
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

nucleoside-triphosphatase activity

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 417417ATP-dependent Clp protease ATP-binding subunit ClpX HAMAP-Rule MF_00175
PRO_0000160333

Regions

Zinc finger15 – 4228C4-type HAMAP-Rule MF_00175
Nucleotide binding127 – 1348ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PIM0 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 09AF6400AA99CCCD

FASTA41747,049
        10         20         30         40         50         60 
MEFLSIGVKI MPRKCSFCNE VENPQRRILA NENDDAFICE YCVEGAYSII YGEEKEFKEP 

        70         80         90        100        110        120 
KQSHNTEFKD ITPKELKAYL DRYVIGQDRA KKVFSVGVYN HYKRLFKAEL QDDDTELFKS 

       130        140        150        160        170        180 
NILLVGPTGS GKTLLAQTLA KFLDVPIAIC DATSLTEAGY VGEDVENILT RLLQAADGDV 

       190        200        210        220        230        240 
QRAQKGIVFI DEIDKIARMS ENRSITRDVS GEGVQQALLK IIEGSLVNIP PRGGRKHPNQ 

       250        260        270        280        290        300 
EFIQIDTSNI LFVCGGAFDG LETILKRKLG DKVVGFFDDA KEENKALLEK IEPDDLVHFG 

       310        320        330        340        350        360 
LIPELIGRLH VIASLNELNE EDMVRILTEP KNAIIKQYQK LFAIDGVNLK FEEDALRAIA 

       370        380        390        400        410 
QLALERKTGA RGLRSIIEEM MVDLMFELPE YKDYDIVITK EVVKDNAKAL LIKRKIS 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL111168 Genomic DNA. Translation: CAL34429.1.
PIRB81446.
RefSeqYP_002343717.1. NC_002163.1.

3D structure databases

ProteinModelPortalQ9PIM0.
SMRQ9PIM0. Positions 72-412.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING192222.Cj0275.

Proteomic databases

PRIDEQ9PIM0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAL34429; CAL34429; Cj0275.
GeneID904600.
KEGGcje:Cj0275.
PATRIC20057471. VBICamJej33762_0269.

Phylogenomic databases

eggNOGCOG1219.
HOGENOMHOG000010093.
KOK03544.
OMAILLDIMY.
OrthoDBEOG625JZK.

Enzyme and pathway databases

BioCycCJEJ192222:GJTS-255-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00175. ClpX.
InterProIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR019489. Clp_ATPase_C.
IPR004487. Clp_protease_ATP-bd_su_ClpX.
IPR027417. P-loop_NTPase.
IPR025943. Sigma_54_int_dom_ATP-bd_2.
IPR010603. Znf_CppX_C4.
[Graphical view]
PANTHERPTHR11262:SF4. PTHR11262:SF4. 1 hit.
PfamPF07724. AAA_2. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
PF06689. zf-C4_ClpX. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
SM01086. ClpB_D2-small. 1 hit.
SM00994. zf-C4_ClpX. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00382. clpX. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCLPX_CAMJE
AccessionPrimary (citable) accession number: Q9PIM0
Secondary accession number(s): Q0PBN0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families