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Q9PIG7 (NDK_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nucleoside diphosphate kinase
Short name=NDK
Short name=NDP kinase
EC=2.7.4.6
Alternative name(s):
Nucleoside-2-P kinase
Gene names
Name:ndk
Ordered Locus Names:Cj0332c
OrganismCampylobacter jejuni
Taxonomic identifier197 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length137 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. HAMAP MF_00451

Catalytic activity

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. HAMAP MF_00451

Cofactor

Magnesium By similarity. HAMAP MF_00451

Subunit structure

Homotetramer By similarity. HAMAP MF_00451

Subcellular location

Cytoplasm By similarity HAMAP MF_00451.

Sequence similarities

Belongs to the NDK family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 137137Nucleoside diphosphate kinase HAMAP MF_00451
PRO_0000136960

Sites

Active site1151Pros-phosphohistidine intermediate By similarity
Binding site91ATP By similarity
Binding site571ATP By similarity
Binding site851ATP By similarity
Binding site911ATP By similarity
Binding site1021ATP By similarity
Binding site1121ATP By similarity

Secondary structure

1 ............................. 137
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9PIG7 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 53EDA6F707B45C32

FASTA13715,142
        10         20         30         40         50         60 
MEKTLSIIKP DAVKKGVIGK ILDRFESNGL RIAAMKKVQL SKEQAENFYA VHKERPFFKD 

        70         80         90        100        110        120 
LVEFMISGPV VVSILEGEGA VLKNRDLMGA TNPKEAKAGT IRADFAESID ANAVHGSDSL 

       130 
ENAKIEIEFF FKPNEIC

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL111168 Genomic DNA. Translation: CAL34483.1.
PIRH81452.
RefSeqYP_002343770.1. NC_002163.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3PJ9X-ray2.10A/B/C/D1-137[»]
ProteinModelPortalQ9PIG7.
SMRQ9PIG7. Positions 1-136.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9PIG7. 48 interactions.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID904656.
GenomeReviewsGene locus Cj0332c in contig AL111168_GR.
KEGGcje:Cj0332c.
PATRIC20057581. VBICamJej33762_0324.

Phylogenomic databases

HOGENOMHBG445152.
OMAERPFFGA.
ProtClustDBPRK00668.

Enzyme and pathway databases

BioCycCJEJ192222:CJ0332C-MONOMER.

Family and domain databases

HAMAPMF_00451. NDP_kinase.
[Tree]
InterProIPR001564. Nucleoside_diP_kinase.
IPR023005. Nucleoside_diP_kinase_AS.
[Graphical view]
Gene3DG3DSA:3.30.70.141. NDK. 1 hit.
KOK00940.
PANTHERPTHR11349. Nuc_diP_kinase_core. 1 hit.
PfamPF00334. NDK. 1 hit.
[Graphical view]
PRINTSPR01243. NUCDPKINASE.
SMARTSM00562. NDK. 1 hit.
[Graphical view]
SUPFAMSSF54919. NDK. 1 hit.
PROSITEPS00469. NDP_KINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNDK_CAMJE
AccessionPrimary (citable) accession number: Q9PIG7
Secondary accession number(s): Q0PBH7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: October 1, 2000
Last modified: January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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