Q9PIF3 (TRPF_CAMJE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	Cj0347

Organism

Campylobacter jejuni

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 199	199	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_0000154350

Sequences

	Sequence		Length	Mass (Da)
	Q9PIF3 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: ACBE754AD6E4B877	FASTA	199	22,481
	10 20 30 40 50 60 MLKLKICGIK DEKNAKDLAF LNIDFFGLIF AKSPRRVSLE QARNLSAIFH EKDKKVVGVF 70 80 90 100 110 120 VDENLEQILR CIKEAKLDGI QIYRTITKEE FEILKVQNVF VWQVISVENS LDLKSEIFAN 130 140 150 160 170 180 LVLFDAKGIL KGGNGISFDW TLLGSYTKDF ILAGGIGLDN VHKAVKTGAK ILDLNSKLED 190 EKGLKDINKI KQILKELKK

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL111168 Genomic DNA. Translation: CAL34498.1.
PIR	B81377.
RefSeq	YP_002343785.1. NC_002163.1.
3D structure databases
ProteinModelPortal	Q9PIF3.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9PIF3. 13 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	904671.
GenomeReviews	Gene locus Cj0347 in contig AL111168_GR.
KEGG	cje:Cj0347.
PATRIC	20057611. VBICamJej33762_0339.
Phylogenomic databases
HOGENOM	HBG554803.
OMA	KAVQTGA.
PhylomeDB	Q9PIF3.
ProtClustDB	CLSK878748.
Enzyme and pathway databases
BioCyc	CJEJ192222:CJ0347-MONOMER.
Family and domain databases
HAMAP	MF_00135. PRAI. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01817.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_CAMJE

Accession

Primary (citable) accession number: Q9PIF3
Secondary accession number(s): Q0PBG2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 25, 2003
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program