Reviewed, UniProtKB/Swiss-Prot Q9PHK9 (HSLV_CAMJE)

Names and origin

Protein names

Recommended name:
    ATP-dependent protease hslV
    EC=3.4.25.-

Gene names

Name:	hslV
Ordered Locus Names:	Cj0663c

Organism

Campylobacter jejuni [Complete proteome] [HAMAP]

Taxonomic identifier

197 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	180 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Protease subunit of a proteasome-like degradation complex By similarity.
Subunit structure	A double ring-shaped homohexamer of hslV is capped on each side by a ring-shaped hslU homohexamer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the peptidase T1B family. HslV subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase Protease Threonine protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis involved in cellular protein catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell proteasome core complex Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction. Source: IntAct threonine-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
fliG	Q0PBJ0	1	EBI-1194908,EBI-1191336

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 180	180	ATP-dependent protease hslV HAMAP MF_00248		PRO_0000148099
Sites
	Active site	5	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9PHK9-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 4FA4E4BA86A7D3F1	FASTA	180	19,592
	10 20 30 40 50 60 MFHATTILAY KGKNKSVIGG DGQVSFGNTV LKGNAVKIRK LNNGKVLAGF AGSTADAFNL 70 80 90 100 110 120 FDMFENLLQS SKGDLLKAAI DFSKEWRKDK YLRKLEAMML VLDRNHIFLL SGTGDVVEPE 130 140 150 160 170 180 DGQIAAIGSG GNYALSAARA LAKHTDLDEE ELVKSSLQIA GEICIYTNTN IKTYVIEDEK

References

[1]

"The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. , van Vliet A.H.M., Whitehead S., Barrell B.G. Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL111168 Genomic DNA. Translation: CAL34804.1.
PIR	A81415.
RefSeq	YP_002344087.1.
3D structure databases
HSSP	HSSP built from PDB template 1M4Y based on UniProtKB Q9WYZ1.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9PHK9. 90 interactions.
Genome annotation databases
GeneID	904986.
GenomeReviews	Gene locus Cj0663c in contig AL111168_GR.
KEGG	cje:Cj0663c.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	Q9PHK9. AADICVY.
Enzyme and pathway databases
BioCyc	CJEJ192222:CJ0663C-MON.
Family and domain databases
HAMAP	MF_00248. [Tree]
InterPro	IPR001353. Proteasome_alpha_beta_su. [Graphical view]
Pfam	PF00227. Proteasome. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HSLV_CAMJE

Accession

Primary (citable) accession number: Q9PHK9
Secondary accession number(s): Q0PAL0

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	October 1, 2000
Last modified:	June 16, 2009
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)