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Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Xylella fastidiosa (strain 9a5c)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei2Nucleophile; for GATase activityUniRule annotation1
Active sitei604For Fru-6P isomerization activityUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminotransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Ordered Locus Names:XF_0141
OrganismiXylella fastidiosa (strain 9a5c)
Taxonomic identifieri160492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
Proteomesi
  • UP000000812 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedUniRule annotation
ChainiPRO_00001354162 – 609Glutamine--fructose-6-phosphate aminotransferase [isomerizing]Add BLAST608

Proteomic databases

PRIDEiQ9PH05.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi160492.XF0141.

Structurei

3D structure databases

ProteinModelPortaliQ9PH05.
SMRiQ9PH05.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 217Glutamine amidotransferase type-2UniRule annotationAdd BLAST216
Domaini285 – 425SIS 1UniRule annotationAdd BLAST141
Domaini458 – 599SIS 2UniRule annotationAdd BLAST142

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiENOG4105C46. Bacteria.
COG0449. LUCA.
KOiK00820.
OMAiGTSHYAG.
OrthoDBiPOG091H0061.

Family and domain databases

CDDicd05008. SIS_GlmS_GlmD_1. 1 hit.
cd05009. SIS_GlmS_GlmD_2. 1 hit.
Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS. 1 hit.
InterProiView protein in InterPro
IPR017932. GATase_2_dom.
IPR035466. GlmS/AgaS_SIS.
IPR035490. GlmS/FrlB_SIS.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
PANTHERiPTHR10937:SF15. PTHR10937:SF15. 1 hit.
PfamiView protein in Pfam
PF01380. SIS. 2 hits.
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiView protein in PROSITE
PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9PH05-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCGIVGAIAG RDVVPVLIEG LKRLEYRGYD SSGIAVLESG SIRRVRRTGR
60 70 80 90 100
VAEMAVAATQ EGFTASLGIG HTRWATHGGV TEANAHPHVS HGVVLVHNGI
110 120 130 140 150
IENHEVQRER LSALGYVFQS QTDTEVIAHL IHYHMQQGDD LLGALQCAVK
160 170 180 190 200
ALTGIYALAV MSEAEPERFV CARMGCPLLI GIGDGEHLVA SDISAVIQAT
210 220 230 240 250
RQVIFLEDGD TAEIRRDGIS IFNAEQCPVE RPLHLSNVSL SSLELGEFRH
260 270 280 290 300
FMQKEIHEQP RVLADTMEAA IDAAGFPPML FGAQAESVFR GITGIQILAC
310 320 330 340 350
GTSYYAGLTA RYWIEAIAGL PCHVEIASEY RYRKAYVNPQ HLVVTISQSG
360 370 380 390 400
ETLDTLEALK YAKALGHRHT LSICNAPDSA IPRISELICY TRAGPEIGVA
410 420 430 440 450
STKAFTTQLV VLFQLAVALG VLRGAVDAEH EAAYLEQLRQ LPCGVQQALN
460 470 480 490 500
LEPQIAAWAE CFASRHHALF LGRGLHYPIA LEGALKLKEI SYIHAEAYPA
510 520 530 540 550
GELKHGPLAL VDADMPVVVI APNDSLLEKV KSNMQEVRAR GGELFVFADQ
560 570 580 590 600
DSHFSESEGL HVIRTLRHTG VLSPLVHTIP VQLLAYHTAL VRGTDVDKPR

NLAKSVTVE
Length:609
Mass (Da):66,145
Last modified:January 23, 2007 - v3
Checksum:i17085FA14A3933B7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003849 Genomic DNA. Translation: AAF82954.1.
PIRiA82844.
RefSeqiWP_010892686.1. NC_002488.3.

Genome annotation databases

EnsemblBacteriaiAAF82954; AAF82954; XF_0141.
GeneIDi1125659.
KEGGixfa:XF_0141.

Similar proteinsi

Entry informationi

Entry nameiGLMS_XYLFA
AccessioniPrimary (citable) accession number: Q9PH05
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: January 23, 2007
Last modified: August 30, 2017
This is version 99 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome