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Protein

Biofilm growth-associated repressor

Gene

bigR

Organism
Xylella fastidiosa (strain 9a5c)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Represses an operon that comprises itself, XF_0764, XF_0765, XF_0766 and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon.1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi51 – 7424H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Biofilm growth-associated repressor
Gene namesi
Name:bigR
Ordered Locus Names:XF_0767
OrganismiXylella fastidiosa (strain 9a5c)
Taxonomic identifieri160492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
Proteomesi
  • UP000000812 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 114114Biofilm growth-associated repressorPRO_0000305336Add
BLAST

Expressioni

Gene expression databases

CollecTFiEXPREG_000017b0.

Interactioni

Protein-protein interaction databases

STRINGi160492.XF0767.

Structurei

Secondary structure

1
114
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi17 – 3216Combined sources
Helixi35 – 4511Combined sources
Helixi51 – 588Combined sources
Helixi64 – 7411Combined sources
Beta strandi77 – 815Combined sources
Beta strandi83 – 853Combined sources
Beta strandi88 – 914Combined sources
Helixi96 – 10611Combined sources
Helixi108 – 1114Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3PQJX-ray2.48A/B/C/D13-114[»]
3PQKX-ray2.09A/B/C/D/E/F13-114[»]
ProteinModelPortaliQ9PFB1.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9PFB1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini17 – 11195HTH arsR-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH arsR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG41080HT. Bacteria.
COG0640. LUCA.
OMAiVSTRREH.
OrthoDBiPOG091H02HD.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001845. HTH_ArsR_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF12840. HTH_20. 1 hit.
[Graphical view]
PRINTSiPR00778. HTHARSR.
SMARTiSM00418. HTH_ARSR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50987. HTH_ARSR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9PFB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNEMRDDTR PHMTREDMEK RANEVANLLK TLSHPVRLML VCTLVEGEFS
60 70 80 90 100
VGELEQQIGI GQPTLSQQLG VLRESGIVET RRNIKQIFYR LTEAKAAQLV
110
NALYTIFCAQ EKQA
Length:114
Mass (Da):12,989
Last modified:October 1, 2000 - v1
Checksum:i3AB9B2C6C5A58CF7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003849 Genomic DNA. Translation: AAF83577.1.
PIRiD82766.
RefSeqiWP_010893290.1. NC_002488.3.

Genome annotation databases

EnsemblBacteriaiAAF83577; AAF83577; XF_0767.
GeneIDi1126301.
KEGGixfa:XF_0767.
PATRICi24131533. VBIXylFas578_0807.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003849 Genomic DNA. Translation: AAF83577.1.
PIRiD82766.
RefSeqiWP_010893290.1. NC_002488.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3PQJX-ray2.48A/B/C/D13-114[»]
3PQKX-ray2.09A/B/C/D/E/F13-114[»]
ProteinModelPortaliQ9PFB1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160492.XF0767.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAF83577; AAF83577; XF_0767.
GeneIDi1126301.
KEGGixfa:XF_0767.
PATRICi24131533. VBIXylFas578_0807.

Phylogenomic databases

eggNOGiENOG41080HT. Bacteria.
COG0640. LUCA.
OMAiVSTRREH.
OrthoDBiPOG091H02HD.

Miscellaneous databases

EvolutionaryTraceiQ9PFB1.

Gene expression databases

CollecTFiEXPREG_000017b0.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR001845. HTH_ArsR_DNA-bd_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF12840. HTH_20. 1 hit.
[Graphical view]
PRINTSiPR00778. HTHARSR.
SMARTiSM00418. HTH_ARSR. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50987. HTH_ARSR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBIGR_XYLFA
AccessioniPrimary (citable) accession number: Q9PFB1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.