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Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Xylella fastidiosa (strain 9a5c)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathwayi: pentose phosphate pathway

This protein is involved in step 2 of the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage).
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Glucose-6-phosphate 1-dehydrogenase (zwf)
  2. 6-phosphogluconolactonase (pgl)
  3. no protein annotated in this organism
This subpathway is part of the pathway pentose phosphate pathway, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage), the pathway pentose phosphate pathway and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciXFAS160492:G1FZ5-970-MONOMER
UniPathwayiUPA00115; UER00409

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6PGL
Gene namesi
Name:pgl
Ordered Locus Names:XF_1063
OrganismiXylella fastidiosa (strain 9a5c)
Taxonomic identifieri160492 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella
Proteomesi
  • UP000000812 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000901101 – 2396-phosphogluconolactonaseAdd BLAST239

Proteomic databases

PRIDEiQ9PEG5

Interactioni

Protein-protein interaction databases

STRINGi160492.XF1063

Structurei

3D structure databases

ProteinModelPortaliQ9PEG5
SMRiQ9PEG5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108Q79 Bacteria
COG0363 LUCA
KOiK01057
OMAiDERWVAP
OrthoDBiPOG091H04M8

Family and domain databases

CDDicd01400 6PGL, 1 hit
InterProiView protein in InterPro
IPR005900 6-phosphogluconolactonase_DevB
IPR006148 Glc/Gal-6P_isomerase
IPR037171 NagB/RpiA_transferase-like
PfamiView protein in Pfam
PF01182 Glucosamine_iso, 1 hit
SUPFAMiSSF100950 SSF100950, 1 hit

Sequencei

Sequence statusi: Complete.

Q9PEG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPPNDARIT LMNYDDPLEW AQSVTRELEN ILLQEITQRG RASLLLSGGT
60 70 80 90 100
TPARVYETLA TRPLDWSKID IGLVDERWLS PQDKDSNAWL VRHTLLEHAK
110 120 130 140 150
HATFLPLIRP GKTLNQCVHD ANLQITHSPP PCAAVLGMGN DGHTASLFPG
160 170 180 190 200
SLDLPKAIST LQPYVALDAT GCPGAGVWPL RITLTPAGLS NIPHRLLLLC
210 220 230
GKQKMQVLET ALSCKDALDY PIRTAIDLPN ARLRVHWCA
Length:239
Mass (Da):26,281
Last modified:October 1, 2000 - v1
Checksum:i2A975549EABC8BCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE003849 Genomic DNA Translation: AAF83873.1
PIRiD82727
RefSeqiWP_010893582.1, NC_002488.3

Genome annotation databases

EnsemblBacteriaiAAF83873; AAF83873; XF_1063
GeneIDi1126603
KEGGixfa:XF_1063
PATRICifig|160492.11.peg.1130

Similar proteinsi

Entry informationi

Entry namei6PGL_XYLFA
AccessioniPrimary (citable) accession number: Q9PEG5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 24, 2001
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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