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Q9PDA6 (CSD_XYLFA) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cysteine desulfurase

EC=2.8.1.7
Gene names
Name:csd
Ordered Locus Names:XF_1473
OrganismXylella fastidiosa (strain 9a5c) [Complete proteome] [HAMAP]
Taxonomic identifier160492 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXylella

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine By similarity.

Catalytic activity

L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor.

Cofactor

Pyridoxal phosphate By similarity.

Sequence similarities

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcysteine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functioncysteine desulfurase activity

Inferred from electronic annotation. Source: UniProtKB-EC

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416Probable cysteine desulfurase
PRO_0000150323

Sites

Active site3741Cysteine persulfide intermediate By similarity

Amino acid modifications

Modified residue2361N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9PDA6 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 8ED62445EB2A4231

FASTA41645,823
        10         20         30         40         50         60 
MDRINTSAAP PTSPDWERLR TDFPLLQRHV HGKPLIYFDN ANTAQKPQAV ITATDTFYRR 

        70         80         90        100        110        120 
HNANISRAVH TLGTEATEAY EATRTALATL LNAPTHELVL CSGTTFAINL IAYSWALPRL 

       130        140        150        160        170        180 
RAGDVILVSR MEHHANIVPW QLIAERTGAR IQVADILPNG TLDLDALHTL MTPQVKLLAI 

       190        200        210        220        230        240 
THVSNVLGTV NPIHDICRQA RQRGITTVVD GSQAAPHRHI DIPAIGCDFY AITGHKLYGP 

       250        260        270        280        290        300 
TGTGALWARR EHLHIMPPFL GGGEMIKEVS FDGTLFNTPP HKFEAGTPNI AGFIGLRAAV 

       310        320        330        340        350        360 
DYVRRIGIEQ IETRETELLA HLTEELQKID GMRLFGTAPN KAAVVSFMIE GTHAHDLATL 

       370        380        390        400        410 
LDLEGVAIRS GQHCAHPLLQ YYGVTATCRA SLAFYNTHEE IERFIAALLK VRKLLG 

« Hide

References

[1]"The genome sequence of the plant pathogen Xylella fastidiosa."
Simpson A.J.G., Reinach F.C., Arruda P., Abreu F.A., Acencio M., Alvarenga R., Alves L.M.C., Araya J.E., Baia G.S., Baptista C.S., Barros M.H., Bonaccorsi E.D., Bordin S., Bove J.M., Briones M.R.S., Bueno M.R.P., Camargo A.A., Camargo L.E.A. expand/collapse author list , Carraro D.M., Carrer H., Colauto N.B., Colombo C., Costa F.F., Costa M.C.R., Costa-Neto C.M., Coutinho L.L., Cristofani M., Dias-Neto E., Docena C., El-Dorry H., Facincani A.P., Ferreira A.J.S., Ferreira V.C.A., Ferro J.A., Fraga J.S., Franca S.C., Franco M.C., Frohme M., Furlan L.R., Garnier M., Goldman G.H., Goldman M.H.S., Gomes S.L., Gruber A., Ho P.L., Hoheisel J.D., Junqueira M.L., Kemper E.L., Kitajima J.P., Krieger J.E., Kuramae E.E., Laigret F., Lambais M.R., Leite L.C.C., Lemos E.G.M., Lemos M.V.F., Lopes S.A., Lopes C.R., Machado J.A., Machado M.A., Madeira A.M.B.N., Madeira H.M.F., Marino C.L., Marques M.V., Martins E.A.L., Martins E.M.F., Matsukuma A.Y., Menck C.F.M., Miracca E.C., Miyaki C.Y., Monteiro-Vitorello C.B., Moon D.H., Nagai M.A., Nascimento A.L.T.O., Netto L.E.S., Nhani A. Jr., Nobrega F.G., Nunes L.R., Oliveira M.A., de Oliveira M.C., de Oliveira R.C., Palmieri D.A., Paris A., Peixoto B.R., Pereira G.A.G., Pereira H.A. Jr., Pesquero J.B., Quaggio R.B., Roberto P.G., Rodrigues V., de Rosa A.J.M., de Rosa V.E. Jr., de Sa R.G., Santelli R.V., Sawasaki H.E., da Silva A.C.R., da Silva A.M., da Silva F.R., Silva W.A. Jr., da Silveira J.F., Silvestri M.L.Z., Siqueira W.J., de Souza A.A., de Souza A.P., Terenzi M.F., Truffi D., Tsai S.M., Tsuhako M.H., Vallada H., Van Sluys M.A., Verjovski-Almeida S., Vettore A.L., Zago M.A., Zatz M., Meidanis J., Setubal J.C.
Nature 406:151-159(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 9a5c.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE003849 Genomic DNA. Translation: AAF84282.1.
PIRD82676.
RefSeqNP_298762.1. NC_002488.3.

3D structure databases

ProteinModelPortalQ9PDA6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING160492.XF1473.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF84282; AAF84282; XF_1473.
GeneID1127019.
KEGGxfa:XF1473.
PATRIC24133050. VBIXylFas578_1553.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0520.
KOK11717.
OMAHCALPVM.
OrthoDBEOG68DD0M.
ProtClustDBCLSK446271.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR010970. Cys_dSase_SufS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR01979. sufS. 1 hit.
PROSITEPS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCSD_XYLFA
AccessionPrimary (citable) accession number: Q9PDA6
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: November 13, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families