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Protein
Submitted name:

Alanine aminotransferase

Gene

aat

Organism
Pyrococcus furiosus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Enzyme and pathway databases

BRENDAi2.6.1.2. 5243.
SABIO-RKQ9P9M8.

Names & Taxonomyi

Protein namesi
Submitted name:
Alanine aminotransferaseImported
Gene namesi
Name:aatImported
OrganismiPyrococcus furiosusImported
Taxonomic identifieri2261 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus

PTM / Processingi

Proteomic databases

PRIDEiQ9P9M8.

Interactioni

Protein-protein interaction databases

STRINGi186497.PF1497.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1XI9X-ray2.33A/B/C/D2-398[»]
ProteinModelPortaliQ9P9M8.
SMRiQ9P9M8. Positions 3-395.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9P9M8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 386356Aminotran_1_2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiarCOG01131. Archaea.
COG0436. LUCA.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9P9M8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIRASKRALS VEYAIRDVVL PARELEKKGI KVIRLNIGDP VKFDFQPPEH
60 70 80 90 100
MKEAYCKAIK EGHNYYGDSE GLPELRKAIV EREKRKNGVD ITPDDVRVTA
110 120 130 140 150
AVTEALQLIF GALLDPGDEI LVPGPSYPPY TGLVKFYGGK PVEYRTIEEE
160 170 180 190 200
DWQPDIDDIR KKITDRTKAI AVINPNNPTG ALYDKKTLEE ILNIAGEYEI
210 220 230 240 250
PVISDEIYDL MTYEGEHISP GSLTKDVPVI VMNGLSKVYF ATGWRLGYMY
260 270 280 290 300
FVDPENKLSE VREAIDRLAR IRLCPNTPAQ FAAIAGLTGP MDYLKEYMKK
310 320 330 340 350
LKERRDYIYK RLNEIPGIST TKPQGAFYIF PKIEVGPWKN DKEFVLDVLH
360 370 380 390
NAHVLFVHGS GFGEYGAGHF RAVFLPPIEI LEEAMDRFEK FMKERLKE
Length:398
Mass (Da):45,335
Last modified:October 1, 2000 - v1
Checksum:i1F1ADAC61364BA92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF163769 Genomic DNA. Translation: AAF65616.1.

Genome annotation databases

GeneIDi1469373.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF163769 Genomic DNA. Translation: AAF65616.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1XI9X-ray2.33A/B/C/D2-398[»]
ProteinModelPortaliQ9P9M8.
SMRiQ9P9M8. Positions 3-395.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi186497.PF1497.

Proteomic databases

PRIDEiQ9P9M8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1469373.

Phylogenomic databases

eggNOGiarCOG01131. Archaea.
COG0436. LUCA.

Enzyme and pathway databases

BRENDAi2.6.1.2. 5243.
SABIO-RKQ9P9M8.

Miscellaneous databases

EvolutionaryTraceiQ9P9M8.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Purification and characterization of the alanine aminotransferase from the hyperthermophilic Archaeon pyrococcus furiosus and its role in alanine production."
    Ward D.E., Kengen S.W., van Der Oost J., de Vos W.M.
    J. Bacteriol. 182:2559-2566(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Cited for: X-RAY CRYSTALLOGRAPHY (2.33 ANGSTROMS) OF 2-398.

Entry informationi

Entry nameiQ9P9M8_9EURY
AccessioniPrimary (citable) accession number: Q9P9M8
Secondary accession number(s): Q7LWY3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: December 9, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.