Reviewed, UniProtKB/Swiss-Prot Q9P931 (PGM_EMENI)

Names and origin

Protein names

Recommended name:
    Phosphoglucomutase
      Short name=PGM
    EC=5.4.2.2
Alternative name(s):
    Glucose phosphomutase

Gene names

Name:	pgmB
ORF Names:	AN2867

Organism

Emericella nidulans (Aspergillus nidulans) [Complete proteome]

Taxonomic identifier

162425 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › Emericella

Protein attributes

Sequence length	556 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucomutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 556	556	Phosphoglucomutase		PRO_0000147794
Sites
	Active site	114	1	Phosphoserine intermediate By similarity
	Metal binding	114	1	Magnesium; via phosphate group By similarity
	Metal binding	279	1	Magnesium By similarity
	Metal binding	281	1	Magnesium By similarity
	Metal binding	283	1	Magnesium By similarity
Experimental info
	Sequence conflict	447 – 459	13	VDNKS…GSTIS → ESTTRAHLLAAPSL Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q9P931-1 [UniParc]. Last modified March 21, 2006. Version 2. Checksum: EDFB1C08219E0775	FASTA	556	60,684
	10 20 30 40 50 60 MSVQTVSIQP FGDQKPGTSG LRKKVKIFQQ ENYTESFLTS IFLSIPEGAQ DAFLVIGGDG 70 80 90 100 110 120 RYYNSDVIQK IAKIGAAYGV KKLIVGQNGI LSTPAASNLI RKRKATGGIL LTASHNPGGP 130 140 150 160 170 180 DNDFGIKYNL TNGAPAPEQV TNKIYEVSKS LTSYKYIDLP EVDTTTVGTR SYGPLEVEVV 190 200 210 220 230 240 HSTEDYVSMM KEIFDFDLIR SFLKKHPDFK VLFDGMHGVT GPYGIDIFVN ELGLPSSSTM 250 260 270 280 290 300 NCIPKPDFGG GHPDPNLVYA HELVEAVDKN GIHFGAASDG DGDRNMIYGA NTFVSPGDSL 310 320 330 340 350 360 AIIAHHAKLI PWFQKHGVDG LARSMPTSGA VDRVAKAQGL QSYEVPTGWK FFCNLFDNKK 370 380 390 400 410 420 MSICGEESFG TGSNHIREKD GVWAIVAWLN VIAGVAEQKP NETPSIASIQ AEFWETYGRT 430 440 450 460 470 480 FFTRYDYENV DSDGANKLIA ALSEKAVDNK SSFVGSTISG RKVVDSGNFA YTDLDGSVTK 490 500 510 520 530 540 NQGLYVKFDD GSRLVVRLSG TGSSGATIRL YVEKYEGDKS KYQMATQDYL KDNVGLALEL 550 LKFKEFVGRE EPDVKT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Developmental and metabolic regulation of the phosphoglucomutase-encoding gene, pgmB, of Aspergillus nidulans." Hoffmann B., LaPaglia S.K., Kubler E., Andermann M., Eckert S.E., Braus G.H. Mol. Gen. Genet. 262:1001-1011(2000) [PubMed: 10660061] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: FGSC 4.
[2]	"Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae." Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S., Braus G.H. , Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L., Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W. Nature 438:1105-1115(2005) [PubMed: 16372000] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FGSC 4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF135264 Genomic DNA. Translation: AAF36531.1. AACD01000051 Genomic DNA. Translation: EAA63438.1.
RefSeq	XP_660471.1.
3D structure databases
HSSP	HSSP built from PDB template 3PMG based on UniProtKB P00949.
ModBase	Search...
Genome annotation databases
GeneID	2874032.
KEGG	ani:AN2867.2.
Enzyme and pathway databases
BRENDA	5.4.2.2. 3859.
Family and domain databases
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGM_EMENI

Accession

Primary (citable) accession number: Q9P931
Secondary accession number(s): Q5B9B3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	March 21, 2006
Last modified:	September 22, 2009
This is version 53 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)