Q9P8T8 (Q9P8T8_HYPJE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
1,2-a-D-mannosidase EMBL AAF34579.1

Gene names

Name:

MDS1 EMBL AAF34579.1

Organism

Hypocrea jecorina (Trichoderma reesei) EMBL AAF34579.1

Taxonomic identifier

51453 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Hypocreomycetidae › Hypocreales › Hypocreaceae › Hypocrea

Protein attributes

Sequence length	523 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1HCU
Gene Ontology (GO)
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	calcium ion binding Inferred from electronic annotation. Source: InterPro mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Glycosylation	105	1	N-linked (GlcNAc...) PDB 1HCU
	Glycosylation	146	1	N-linked (GlcNAc...) PDB 1HCU
	Glycosylation	250	1	N-linked (GlcNAc...) PDB 1HCU

Sequences

	Sequence		Length	Mass (Da)
	Q9P8T8 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 1BD6655BED441878	FASTA	523	56,206
	10 20 30 40 50 60 MRFPSSSVLA LGLIGPALAY PKPGATKRGS PNPTRAAAVK AAFQTSWNAY HHFAFPHDDL 70 80 90 100 110 120 HPVSNSFDDE RNGWGSSAID GLDTAILMGD ADIVNTILQY VPQINFTTTA VANQGSSVFE 130 140 150 160 170 180 TNIRYLGGLL SAYDLLRGPF SSLATNQTLV NSLLRQAQTL ANGLKVAFTT PSGVPDPTVF 190 200 210 220 230 240 FNPTVRRSGA SSNNVAEIGS LVLEWTRLSD LTGNPQYAQL AQKGESYLLN PKGSPEAWPG 250 260 270 280 290 300 LIGTFVSTSN GTFQDSSGSW SGLMDSFYEY LIKMYLYDPV AFAHYKDRWV LGADSTIGHL 310 320 330 340 350 360 GSHPSTRKDL TFLSSYNGQS TSPNSGHLAS FGGGNFILGG ILLNEQKYID FGIKLASSYF 370 380 390 400 410 420 GTYTQTASGI GPEGFAWVDS VTGAGGSPPS SQSGFYSSAG FWVTAPYYIL RPETLESLYY 430 440 450 460 470 480 AYRVTGDSKW QDLAWEALSA IEDACRAGSA YSSINDVTQA NGGGASDDME SFWFAEALKY 490 500 510 520 AYLIFAEESD VQVQATGGNK FVFNTEAHPF SIRSSSRRGG HLA

References

[1]	"Molecular cloning and enzymatic characterization of a Trichoderma reesei 1,2-alpha-D-mannosidase." Maras M., Callewaert N., Piens K., Claeyssens M., Martinet W., Dewaele S., Contreras H., Dewerte I., Penttila M., Contreras R. J. Biotechnol. 77:255-263(2000) [PubMed: 10682284] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Trichoderma reesei alpha-1,2-mannosidase: structural basis for the cleavage of four consecutive mannose residues." Van Petegem F., Contreras H., Contreras R., Van Beeumen J. J. Mol. Biol. 312:157-165(2001) [PubMed: 11545593] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.37 ANGSTROMS) OF 25-523, GLYCOSYLATION AT ASN-105; ASN-146 AND ASN-250.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF212153 mRNA. Translation: AAF34579.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1HCU	X-ray	2.37	A/B/C/D	27-523	[»]

ProteinModelPortal

Q9P8T8.

SMR

Q9P8T8. Positions 26-514.

ModBase

Search...

Protein family/group databases

CAZy

GH47. Glycoside Hydrolase Family 47.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR001382. Glyco_hydro_47.
[Graphical view]

Gene3D

G3DSA:1.50.10.50. Glyco_hydro_47. 1 hit.

PANTHER

PTHR11742. Glyco_hydro_47. 1 hit.

Pfam

PF01532. Glyco_hydro_47. 1 hit.
[Graphical view]

PRINTS

PR00747. GLYHDRLASE47.

SUPFAM

SSF48225. Glyco_hydro_47. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q9P8T8_HYPJE

Accession

Primary (citable) accession number: Q9P8T8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	October 19, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)