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Protein

Probable ribonuclease P protein subunit 1

Gene

SPBC1703.01c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. ribonuclease P RNA binding Source: GO_Central

GO - Biological processi

  1. mRNA cleavage Source: InterPro
  2. RNA phosphodiester bond hydrolysis Source: GOC
  3. RNA phosphodiester bond hydrolysis, endonucleolytic Source: GOC
  4. rRNA processing Source: PomBase
  5. tRNA processing Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Probable ribonuclease P protein subunit 1 (EC:3.1.26.5)
Gene namesi
ORF Names:SPBC1703.01c, SPBP4H10.22c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1703.01c.
PomBaseiSPBC1703.01c.

Subcellular locationi

  1. Nucleusnucleolus 1 Publication

GO - Cellular componenti

  1. nucleolar ribonuclease P complex Source: PomBase
  2. nucleolus Source: PomBase
  3. ribonuclease MRP complex Source: PomBase
  4. ribonuclease P complex Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 217217Probable ribonuclease P protein subunit 1PRO_0000128423Add
BLAST

Proteomic databases

MaxQBiQ9P7W9.

Interactioni

Protein-protein interaction databases

STRINGi4896.SPBC1703.01c-1.

Structurei

3D structure databases

ProteinModelPortaliQ9P7W9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG255667.
InParanoidiQ9P7W9.
KOiK03538.
OMAiPKSECVF.
OrthoDBiEOG7N0CGM.
PhylomeDBiQ9P7W9.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
InterProiIPR002730. RNase_P/MRP_p29.
IPR016848. RNase_P/MRP_p29-subunit.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamiPF01868. UPF0086. 1 hit.
[Graphical view]
PIRSFiPIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
SMARTiSM00538. POP4. 1 hit.
[Graphical view]
SUPFAMiSSF101744. SSF101744. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9P7W9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADPLYSSLK TVNSTSKVTP ESLVFQTKIL TPEEAKNVIN EKIAFKPLLL
60 70 80 90 100
VPSLNLEKQG DRKESVASKK RKKLSSKEKK KLQLNVVPKI ADYSQFKHLH
110 120 130 140 150
SMWCSYILEV IAGCTGESLM AKLAKAEYQG AYMQVLRSKS TTRVGLEGIC
160 170 180 190 200
IHESKHMLSL ITKENRVVRV PKQDSVMKVI VDVPQRKLVF ELYTQHLLLR
210
AGDRSNKRFK SKNTIDL
Length:217
Mass (Da):24,629
Last modified:March 29, 2004 - v2
Checksum:i441B0EADE8E8A7CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAD99134.2.
PIRiT50314.
RefSeqiXP_001713139.1. XM_001713087.2.

Genome annotation databases

EnsemblFungiiSPBC1703.01c.1; SPBC1703.01c.1:pep; SPBC1703.01c.
GeneIDi2539947.
KEGGispo:SPBC1703.01c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAD99134.2.
PIRiT50314.
RefSeqiXP_001713139.1. XM_001713087.2.

3D structure databases

ProteinModelPortaliQ9P7W9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4896.SPBC1703.01c-1.

Proteomic databases

MaxQBiQ9P7W9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC1703.01c.1; SPBC1703.01c.1:pep; SPBC1703.01c.
GeneIDi2539947.
KEGGispo:SPBC1703.01c.

Organism-specific databases

EuPathDBiFungiDB:SPBC1703.01c.
PomBaseiSPBC1703.01c.

Phylogenomic databases

eggNOGiNOG255667.
InParanoidiQ9P7W9.
KOiK03538.
OMAiPKSECVF.
OrthoDBiEOG7N0CGM.
PhylomeDBiQ9P7W9.

Miscellaneous databases

NextBioi20801090.
PROiQ9P7W9.

Family and domain databases

Gene3Di2.30.30.210. 1 hit.
InterProiIPR002730. RNase_P/MRP_p29.
IPR016848. RNase_P/MRP_p29-subunit.
IPR023534. Rof/RNase_P-like.
[Graphical view]
PfamiPF01868. UPF0086. 1 hit.
[Graphical view]
PIRSFiPIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
SMARTiSM00538. POP4. 1 hit.
[Graphical view]
SUPFAMiSSF101744. SSF101744. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRNP1_SCHPO
AccessioniPrimary (citable) accession number: Q9P7W9
Secondary accession number(s): Q7Z988
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: March 29, 2004
Last modified: April 29, 2015
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.