Reviewed, UniProtKB/Swiss-Prot Q9P7W9 (RNP1_SCHPO)

Names and origin

Protein names

Recommended name:
    Probable ribonuclease P protein subunit 1
    EC=3.1.26.5

Gene names

ORF Names:

SPBC1703.01c, SPBP4H10.22c

Organism

Schizosaccharomyces pombe (Fission yeast) [Complete proteome]

Taxonomic identifier

4896 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
Subcellular location	Nucleus › nucleolus Ref.2.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Nucleus
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleolar ribonuclease P complex Inferred from electronic annotation. Source: InterPro ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 217	217	Probable ribonuclease P protein subunit 1		PRO_0000128423

Sequences

	Sequence		Length	Mass (Da)
	Q9P7W9-1 [UniParc]. Last modified March 29, 2004. Version 2. Checksum: 441B0EADE8E8A7CD	FASTA	217	24,629
	10 20 30 40 50 60 MADPLYSSLK TVNSTSKVTP ESLVFQTKIL TPEEAKNVIN EKIAFKPLLL VPSLNLEKQG 70 80 90 100 110 120 DRKESVASKK RKKLSSKEKK KLQLNVVPKI ADYSQFKHLH SMWCSYILEV IAGCTGESLM 130 140 150 160 170 180 AKLAKAEYQG AYMQVLRSKS TTRVGLEGIC IHESKHMLSL ITKENRVVRV PKQDSVMKVI 190 200 210 VDVPQRKLVF ELYTQHLLLR AGDRSNKRFK SKNTIDL

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972.

[2]

"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed: 16823372] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329671 Genomic DNA. Translation: CAD99134.2.
PIR	T50314.
RefSeq	XP_001713139.1.
3D structure databases
SMR	Q9P7W9. Positions 121-211.
ModBase	Search...
Genome annotation databases
GeneID	2539947.
KEGG	spo:SPBC1703.01c.
Organism-specific databases
GeneDB_Spombe	SPBC1703.01c.
Phylogenomic databases
eggNOG	fuNOG08457.
OrthoDB	EOG90031H.
PhylomeDB	Q9P7W9.
Enzyme and pathway databases
BRENDA	3.1.26.5. 653.
Gene expression databases
ArrayExpress	Q9P7W9.
Family and domain databases
InterPro	IPR016848. RNase_P/MRP_p29-subunit_euk. IPR002730. RNase_P/MRP_p29_euk/arc. [Graphical view]
Gene3D	G3DSA:2.30.30.210. RNase_P_Rpp29. 1 hit.
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
PIRSF	PIRSF027081. RNase_P/MRP_p29_subunit. 1 hit.
SMART	SM00538. POP4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNP1_SCHPO

Accession

Primary (citable) accession number: Q9P7W9
Secondary accession number(s): Q7Z988

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2004
Last sequence update:	March 29, 2004
Last modified:	January 19, 2010
This is version 44 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)