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Protein

Uncharacterized membrane protein C977.17

Gene

SPAC977.17

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

ReactomeiR-SPO-432030. Transport of glycerol from adipocytes to the liver by Aquaporins.
R-SPO-432040. Vasopressin regulates renal water homeostasis via Aquaporins.
R-SPO-432047. Passive transport by Aquaporins.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized membrane protein C977.17
Gene namesi
ORF Names:SPAC977.17
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC977.17.
PomBaseiSPAC977.17.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 313313CytoplasmicSequence analysisAdd
BLAST
Transmembranei314 – 33421HelicalSequence analysisAdd
BLAST
Topological domaini335 – 34612ExtracellularSequence analysisAdd
BLAST
Transmembranei347 – 36721HelicalSequence analysisAdd
BLAST
Topological domaini368 – 38821CytoplasmicSequence analysisAdd
BLAST
Transmembranei389 – 40921HelicalSequence analysisAdd
BLAST
Topological domaini410 – 44435ExtracellularSequence analysisAdd
BLAST
Transmembranei445 – 46521HelicalSequence analysisAdd
BLAST
Topological domaini466 – 4738CytoplasmicSequence analysis
Transmembranei474 – 49421HelicalSequence analysisAdd
BLAST
Topological domaini495 – 53238ExtracellularSequence analysisAdd
BLAST
Transmembranei533 – 55321HelicalSequence analysisAdd
BLAST
Topological domaini554 – 59845CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 598598Uncharacterized membrane protein C977.17PRO_0000310367Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi279726. 39 interactions.
MINTiMINT-4706334.

Structurei

3D structure databases

ProteinModelPortaliQ9P7T9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi371 – 3733NPA 1
Motifi501 – 5033NPA 2

Domaini

Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000000829.
InParanoidiQ9P7T9.
KOiK03441.
OMAiWSSITEF.
OrthoDBiEOG72JWSQ.
PhylomeDBiQ9P7T9.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P7T9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVPLRFSTP SSSPSASDNE SVHDDGPTTE LDTFNTTDVP RRVNTTKARQ
60 70 80 90 100
MRPKNTLKVA FSSPNLKGLD NTADSDSQPW LGGYLAGRLE DISGQSRRNY
110 120 130 140 150
VDPYYEELNA GRRPNKPVWS LNGPLPHVLG NSVVEKISQK NQEARSRANS
160 170 180 190 200
RVNSRANSRA NSSVSLAGMD GSPNWKRKMK SAVFGSRVKL NDEEAQLPRN
210 220 230 240 250
KSSVSIAEQA ASRPKVSFSL QSSRQPSIAE EQPQTQRKSS AITVEHAENA
260 270 280 290 300
EPETPRNNVS FSRKPSIAEQ DSSQDITMPP NEIIAEESLD SGSDTETLYL
310 320 330 340 350
NYWCKIRHFF REGFAEFLGT LVLVVFGVGS NLQATVTNGA GGSFESLSFA
360 370 380 390 400
WGFGCMLGVY IAGGISGGHV NPAVTISLAI FRKFPWYKVP IYIFFQIWGA
410 420 430 440 450
FFGGALAYGY HWSSITEFEG GKDIRTPATG GCLYTNPKPY VTWRNAFFDE
460 470 480 490 500
FIGTAVLVGC LFAILDDTNS PPTQGMTAFI VGLLIAAIGM ALGYQTSFTL
510 520 530 540 550
NPARDLGPRM FAWWIGYGPH SFHLYHWWWT WGAWGGTIGG GIAGGLIYDL
560 570 580 590
VIFTGPESPL NYPDNGFIDK KVHQITAKFE KEEEVENLEK TDSPIENN
Length:598
Mass (Da):65,816
Last modified:October 1, 2000 - v1
Checksum:i182AC74BFC1CD079
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB69639.1.
PIRiT50288.
RefSeqiNP_592788.1. NM_001018188.2.

Genome annotation databases

EnsemblFungiiSPAC977.17.1; SPAC977.17.1:pep; SPAC977.17.
GeneIDi2543301.
KEGGispo:SPAC977.17.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB69639.1.
PIRiT50288.
RefSeqiNP_592788.1. NM_001018188.2.

3D structure databases

ProteinModelPortaliQ9P7T9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279726. 39 interactions.
MINTiMINT-4706334.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC977.17.1; SPAC977.17.1:pep; SPAC977.17.
GeneIDi2543301.
KEGGispo:SPAC977.17.

Organism-specific databases

EuPathDBiFungiDB:SPAC977.17.
PomBaseiSPAC977.17.

Phylogenomic databases

HOGENOMiHOG000000829.
InParanoidiQ9P7T9.
KOiK03441.
OMAiWSSITEF.
OrthoDBiEOG72JWSQ.
PhylomeDBiQ9P7T9.

Enzyme and pathway databases

ReactomeiR-SPO-432030. Transport of glycerol from adipocytes to the liver by Aquaporins.
R-SPO-432040. Vasopressin regulates renal water homeostasis via Aquaporins.
R-SPO-432047. Passive transport by Aquaporins.

Miscellaneous databases

PROiQ9P7T9.

Family and domain databases

Gene3Di1.20.1080.10. 1 hit.
InterProiIPR023271. Aquaporin-like.
IPR000425. MIP.
IPR022357. MIP_CS.
[Graphical view]
PANTHERiPTHR19139. PTHR19139. 1 hit.
PfamiPF00230. MIP. 1 hit.
[Graphical view]
PRINTSiPR00783. MINTRINSICP.
SUPFAMiSSF81338. SSF81338. 1 hit.
TIGRFAMsiTIGR00861. MIP. 1 hit.
PROSITEiPS00221. MIP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiYI7H_SCHPO
AccessioniPrimary (citable) accession number: Q9P7T9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2000
Last modified: June 8, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.