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Q9P7S5 (UBP7_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable ubiquitin carboxyl-terminal hydrolase 7

EC=3.4.19.12
Alternative name(s):
Deubiquitinating enzyme 7
Ubiquitin thioesterase 7
Ubiquitin-specific-processing protease 7
Gene names
Name:ubp7
ORF Names:SPAC23G3.08c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length875 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sequence similarities

Belongs to the peptidase C19 family.

Contains 1 UBP-type zinc finger.

Contains 1 USP domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 875875Probable ubiquitin carboxyl-terminal hydrolase 7
PRO_0000080608

Regions

Domain208 – 875668USP
Zinc finger81 – 14969UBP-type

Sites

Active site2171Nucleophile By similarity
Active site8121Proton acceptor By similarity

Amino acid modifications

Modified residue3331Phosphoserine Ref.2
Modified residue3371Phosphoserine Ref.2
Modified residue4861Phosphoserine Ref.2
Modified residue4931Phosphoserine Ref.2
Modified residue6451Phosphoserine Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q9P7S5 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: B4E4CFAC9A440D54

FASTA87598,377
        10         20         30         40         50         60 
MPHSNTLIVP STNPFDDPSS IKNGLNNLTS SELVNQMKKE SLAASVKTPS TPPKECSHLK 

        70         80         90        100        110        120 
KGVKLSHLKG NARALRDPSK HLCFICTTEK IKREDYELTL CANCGYLFCC NHESDHSRKH 

       130        140        150        160        170        180 
FEKNKKHCVF VNIITLKCHC YSCDADIVIF DKKNLVVRDV QQFICSNLVS SLTKAPNVLK 

       190        200        210        220        230        240 
SNSSHFKKEK KSKHSSGKSS KKYKVISPGL KNLGATCFFN STLQVLCACE ALHDVISPFQ 

       250        260        270        280        290        300 
YSHSSVIVRK LTKSPESSLL SAFIKFLETF YKSDGTISVY RPTTFFGEFR RLHPQFSESV 

       310        320        330        340        350        360 
QQDAHELLRL LLDDLISEEF RVLRFNLNSV SRSLQLSPCL TDDEQLSKSL TSFKQVNVTD 

       370        380        390        400        410        420 
ASLSPNSHNT SDNEQNNEDY VSVSSLVGSE TEDITYSKEL SQSSDSSQHQ HDSFLPANSS 

       430        440        450        460        470        480 
PLAASSTKSL PSSELLDSSS DKGQQVFKGQ HEVAGTNSFE DPNSHFNVSN SSNHEEASPK 

       490        500        510        520        530        540 
KEVLKSPQFQ RRSLDILRLG ELSSDDMMLD KATMDEFSSS LVIKSIFTGR LTSVVMCQSC 

       550        560        570        580        590        600 
NEITNTPEPI QDLSIPIHYP SSRVSRRHRF HRALRSRFSR SPKKSSVKIV VDNANDDTDQ 

       610        620        630        640        650        660 
APTTNSSSLN ENLLGGHASE NDKSLKQSPF QKLTRRLSDL SVNSSGQISK QDFDNSNSIF 

       670        680        690        700        710        720 
SESSLSSPII EEPKTLIDCL KNFTHVEELS GENMFACENC CNQPNEVGSP AKGGLTSDND 

       730        740        750        760        770        780 
KYSFNNSVYR NAYKRMLLDD PLPPVFIIHL KRFFQEISHD GYANPKKISD FIEFEQELDL 

       790        800        810        820        830        840 
NEFVMPHLRA SSSFRYRLFG VIVHSGTLNY GHYVAYVLSH KFLDLSAPST NSKDFRSEAG 

       850        860        870 
IPERRWLYIS DNIVRESSWD EVSKVEAYML FYERV 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Phosphoproteome analysis of fission yeast."
Wilson-Grady J.T., Villen J., Gygi S.P.
J. Proteome Res. 7:1088-1097(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-333; SER-337; SER-486; SER-493 AND SER-645, IDENTIFICATION BY MASS SPECTROMETRY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329670 Genomic DNA. Translation: CAB72233.1.
PIRT50182.
RefSeqNP_593108.1. NM_001018505.2.

3D structure databases

ProteinModelPortalQ9P7S5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid278336. 16 interactions.
MINTMINT-4706238.
STRING4896.SPAC23G3.08c-1.

Proteomic databases

MaxQBQ9P7S5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC23G3.08c.1; SPAC23G3.08c.1:pep; SPAC23G3.08c.
GeneID2541845.
KEGGspo:SPAC23G3.08c.

Organism-specific databases

PomBaseSPAC23G3.08c.

Phylogenomic databases

eggNOGCOG5533.
KOK11844.
OMAFACENCC.
OrthoDBEOG7PCJV3.
PhylomeDBQ9P7S5.

Family and domain databases

Gene3D3.30.40.10. 1 hit.
InterProIPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR028889. UCH/PAN2.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view]
PfamPF00443. UCH. 1 hit.
PF02148. zf-UBP. 1 hit.
[Graphical view]
PROSITEPS00972. USP_1. 1 hit.
PS00973. USP_2. 1 hit.
PS50235. USP_3. 1 hit.
PS50271. ZF_UBP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20802933.
PROQ9P7S5.

Entry information

Entry nameUBP7_SCHPO
AccessionPrimary (citable) accession number: Q9P7S5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

Peptidase families

Classification of peptidase families and list of entries