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Protein

DNA replication complex GINS protein sld5

Gene

sld5

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization.1 Publication

GO - Biological processi

Keywordsi

Biological processChromosome partition, DNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication complex GINS protein sld5
Gene namesi
Name:sld5
ORF Names:SPBP4H10.21c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBP4H10.21c
PomBaseiSPBP4H10.21c sld5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002554341 – 214DNA replication complex GINS protein sld5Add BLAST214

Proteomic databases

PaxDbiQ9P7C8
PRIDEiQ9P7C8

Interactioni

Subunit structurei

Component of the GINS complex which is a heterotetramer of sld5, psf1, psf2 and psf3. Interacts with sld5.1 Publication

Protein-protein interaction databases

BioGridi277879, 5 interactors
IntActiQ9P7C8, 1 interactor
MINTiQ9P7C8
STRINGi4896.SPBP4H10.21c.1

Structurei

3D structure databases

ProteinModelPortaliQ9P7C8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GINS4/SLD5 family.Curated

Phylogenomic databases

HOGENOMiHOG000215319
InParanoidiQ9P7C8
KOiK10735
OMAiVSIHRME
OrthoDBiEOG092C50L6
PhylomeDBiQ9P7C8

Family and domain databases

CDDicd11711 GINS_A_Sld5, 1 hit
InterProiView protein in InterPro
IPR021151 GINS_A
IPR036224 GINS_bundle-like_dom_sf
IPR008591 GINS_Sld5
IPR031633 SLD5_C
IPR038749 Sld5_GINS_A
PANTHERiPTHR21206 PTHR21206, 1 hit
PfamiView protein in Pfam
PF05916 Sld5, 1 hit
PF16922 SLD5_C, 1 hit
PIRSFiPIRSF007764 Sld5, 1 hit
SUPFAMiSSF158573 SSF158573, 1 hit

Sequencei

Sequence statusi: Complete.

Q9P7C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEWDADDLLI EPTTEVENDY EDLCTQWVNE RMAPDLLPFA EEIVSRVLDR
60 70 80 90 100
IEAQRETLQL AIGTSSATSY RSVLMQTELE RVKFVLRSYM RTRINKIDKY
110 120 130 140 150
AQYIQSHPNL LLYLSSPERQ YLLRHQQIVH RHYMDSFLRE VPAKMNKLDD
160 170 180 190 200
KVGNLSMVAS PDMDTAVFCV VNESVEENFR VSENEYITLD KGDVLILRYS
210
VISDYLRLGV VSLI
Length:214
Mass (Da):24,989
Last modified:October 1, 2000 - v1
Checksum:i9B1C7E50A471891F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAB83179.1
RefSeqiNP_596195.1, NM_001022114.2

Genome annotation databases

EnsemblFungiiSPBP4H10.21c.1; SPBP4H10.21c.1:pep; SPBP4H10.21c
GeneIDi2541368
KEGGispo:SPBP4H10.21c

Similar proteinsi

Entry informationi

Entry nameiSLD5_SCHPO
AccessioniPrimary (citable) accession number: Q9P7C8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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