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Protein

Probable mitochondrial chaperone bcs1

Gene

SPAC644.07

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Chaperone necessary for the assembly of mitochondrial respiratory chain complex III.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi249 – 2568ATPSequence analysis

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable mitochondrial chaperone bcs1
Alternative name(s):
BCS1-like protein
Gene namesi
ORF Names:SPAC644.07
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC644.07.
PomBaseiSPAC644.07.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2020Mitochondrial intermembraneSequence analysisAdd
BLAST
Transmembranei21 – 4121HelicalSequence analysisAdd
BLAST
Topological domaini42 – 449408Mitochondrial matrixSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • mitochondrial inner membrane Source: PomBase
  • mitochondrion Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Probable mitochondrial chaperone bcs1PRO_0000084776Add
BLAST

Proteomic databases

MaxQBiQ9P6Q3.

Interactioni

Protein-protein interaction databases

BioGridi280077. 8 interactions.
MINTiMINT-4704575.

Structurei

3D structure databases

ProteinModelPortaliQ9P6Q3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AAA ATPase family. BCS1 subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000198799.
InParanoidiQ9P6Q3.
KOiK08900.
OMAiFMTTNHP.
OrthoDBiEOG7PVWZR.
PhylomeDBiQ9P6Q3.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027243. BCS1/plant_AAA_ATPases.
IPR014851. BCS1_N.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR23070:SF17. PTHR23070:SF17. 1 hit.
PfamiPF00004. AAA. 1 hit.
PF08740. BCS1_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM01024. BCS1_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00674. AAA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P6Q3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNIGAADAA TSSGISGLLS GNSFLGAGIG LMGFGAGLAI LRRGLISGAS
60 70 80 90 100
LVKRRMLVSV EIPSKEKSYN AFLHWMSTVP KRYSNQLAVE SNRQLKMPQN
110 120 130 140 150
AREKPDKQVA NRIFSLVPGP GKHYIKYKKC WIQVERERSN RLQDLTTGTP
160 170 180 190 200
WETITLTTLS RDRGIFSELL LEAQKFMQSA QKNKTTIYTA WATEWKPFGH
210 220 230 240 250
PRSKRMLSSV VLESNVKKMI TDDVHDFLRN SQWYDTRGIP YRRGYLLYGP
260 270 280 290 300
PGSGKTSFLY ALAGELDYDI CVLNLAEKGL TDDRLNHLLS NVPPKAVVLL
310 320 330 340 350
EDVDSAFQGR ERSGEVGFHA NVTFSGLLNA LDGVTSSDER IIFMTTNHPE
360 370 380 390 400
KLDPALVRPG RVDVKAYLGN ATPEQVREMF TRFYGHSPEM ADDLSDIVCP
410 420 430 440
KNTSMASLQG LFVMNKSSPA DAVDMAKELP DNPPSTPFSF NVHRKSLSV
Length:449
Mass (Da):49,856
Last modified:October 1, 2000 - v1
Checksum:iD111D04B3764B87D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti113 – 1131I → F in BAA13798 (PubMed:9501991).Curated
Sequence conflicti412 – 4121F → L in BAA13798 (PubMed:9501991).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB90134.1.
D89136 mRNA. Translation: BAA13798.1.
PIRiT42406.
RefSeqiNP_593875.1. NM_001019305.2.

Genome annotation databases

EnsemblFungiiSPAC644.07.1; SPAC644.07.1:pep; SPAC644.07.
GeneIDi2543663.
KEGGispo:SPAC644.07.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB90134.1.
D89136 mRNA. Translation: BAA13798.1.
PIRiT42406.
RefSeqiNP_593875.1. NM_001019305.2.

3D structure databases

ProteinModelPortaliQ9P6Q3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi280077. 8 interactions.
MINTiMINT-4704575.

Proteomic databases

MaxQBiQ9P6Q3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC644.07.1; SPAC644.07.1:pep; SPAC644.07.
GeneIDi2543663.
KEGGispo:SPAC644.07.

Organism-specific databases

EuPathDBiFungiDB:SPAC644.07.
PomBaseiSPAC644.07.

Phylogenomic databases

HOGENOMiHOG000198799.
InParanoidiQ9P6Q3.
KOiK08900.
OMAiFMTTNHP.
OrthoDBiEOG7PVWZR.
PhylomeDBiQ9P6Q3.

Miscellaneous databases

PROiQ9P6Q3.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR003959. ATPase_AAA_core.
IPR003960. ATPase_AAA_CS.
IPR027243. BCS1/plant_AAA_ATPases.
IPR014851. BCS1_N.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR23070:SF17. PTHR23070:SF17. 1 hit.
PfamiPF00004. AAA. 1 hit.
PF08740. BCS1_N. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM01024. BCS1_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00674. AAA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Identification of open reading frames in Schizosaccharomyces pombe cDNAs."
    Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.
    DNA Res. 4:363-369(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 31-449.
    Strain: PR745.

Entry informationi

Entry nameiBCS1_SCHPO
AccessioniPrimary (citable) accession number: Q9P6Q3
Secondary accession number(s): P78787
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: October 1, 2000
Last modified: June 8, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.