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Protein

Glutathione S-transferase 3

Gene

gst3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May have a role in the detoxification of various heavy metals.1 Publication

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

  • glutathione peroxidase activity Source: PomBase
  • glutathione transferase activity Source: PomBase

GO - Biological processi

Keywordsi

Molecular functionTransferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase 3 (EC:2.5.1.18)
Alternative name(s):
GST-III
Gene namesi
Name:gst3
ORF Names:SPAC688.04c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC688.04c
PomBaseiSPAC688.04c gst3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001859861 – 242Glutathione S-transferase 3Add BLAST242

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei228Phosphoserine1 Publication1
Modified residuei232Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9P6M1
PaxDbiQ9P6M1
PRIDEiQ9P6M1

PTM databases

iPTMnetiQ9P6M1

Expressioni

Inductioni

By heavy metals such as cadmium and mercury.1 Publication

Interactioni

Subunit structurei

Interacts with sad1.1 Publication

Protein-protein interaction databases

BioGridi279899, 7 interactors
IntActiQ9P6M1, 1 interactor
STRINGi4896.SPAC688.04c.1

Structurei

3D structure databases

ProteinModelPortaliQ9P6M1
SMRiQ9P6M1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 79GST N-terminalAdd BLAST79
Domaini85 – 234GST C-terminalAdd BLAST150

Sequence similaritiesi

Belongs to the GST superfamily.Curated

Phylogenomic databases

HOGENOMiHOG000125753
InParanoidiQ9P6M1
KOiK00799
OMAiLTGADFM
OrthoDBiEOG092C40MQ

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9P6M1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIVLHHLKNS RSTRIVWMLE ELKVPYEIKV YDRVDGRAPP AYTKLSPLGK
60 70 80 90 100
SPIVVDDGVT YIESAAILEH LVRKYGPSFK PSEEDVAELE KYELWMHFSE
110 120 130 140 150
ASLMPFIWAS HVLDLSVNMT PIFFRYIVRQ FVNGIKSKYL SKETFLNLDY
160 170 180 190 200
IDNHLASNEY FAGEQFTAAD PQMCFPIFAA QRDYLSQKPY KNIKRWMRVV
210 220 230 240
SDRPACRIAA EKVEDNTLTL FSDVERYSHP PTPPPEQVRS DE
Length:242
Mass (Da):28,113
Last modified:April 18, 2012 - v3
Checksum:i42324A6B9B672938
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY034792 Genomic DNA Translation: AAK58430.1
CU329670 Genomic DNA Translation: CAB90771.3
RefSeqiNP_594063.3, NM_001019487.3

Genome annotation databases

EnsemblFungiiSPAC688.04c.1; SPAC688.04c.1:pep; SPAC688.04c
GeneIDi2543479
KEGGispo:SPAC688.04c

Similar proteinsi

Entry informationi

Entry nameiGST3_SCHPO
AccessioniPrimary (citable) accession number: Q9P6M1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: April 18, 2012
Last modified: May 23, 2018
This is version 123 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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