Q9P6J6 (BGLS_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative beta-glucosidase
EC=3.2.1.21

Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase

Gene names

ORF Names:

SPBC1683.04

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	832 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.
Subcellular location	Cytoplasm Ref.2.
Sequence similarities	Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Glycosidase Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular carbohydrate catabolic process Inferred by curator. Source: GeneDB_Spombe cellular catabolic process Non-traceable author statement. Source: GeneDB_Spombe
Cellular component	cytosol Inferred from direct assay. Source: GeneDB_Spombe
Molecular function	beta-glucosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 832	832	Putative beta-glucosidase		PRO_0000363374
Sites
	Active site	225	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9P6J6 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 24C8EF2B248BB02F	FASTA	832	93,169
	10 20 30 40 50 60 MMEHDVEDLI NQLDISEKAM LLSGTDLWHT AAIPRLNIPS IRLSDGPNGI RGTSFFNSSP 70 80 90 100 110 120 SACFPCGTAL GATFDKKLLF EVGEYLAEEA KAKGVSVVLG PTVNIHRGPL NGRGFESFSE 130 140 150 160 170 180 DSTLSGLAAS YVILGLQSKN VQACIKHFVC NDMEDERNSV SIDVSQRALR EVYLMPFQLA 190 200 210 220 230 240 CKYSNFKSLM TSYNKVNGEH VSQSRILLDN ILRKEWEWKG TIISDWFGTY SLKKAIDAGL 250 260 270 280 290 300 DLEMPGKPRF RNVNTIQHLV GSKELSESIL DERAKNVLKL VKHSWQNTEA ENHCELNNDS 310 320 330 340 350 360 SCLREALKKF ASQSIVLLKN KKKLLPLSRK GTFAVIGPNA KVCNYSGGGS ANLKPYYTVS 370 380 390 400 410 420 MYDGIAAKID GVPEYALGCH NYLNLPNIAN LLVNPRTGKH GYVAKFYLEP ATSENRTLID 430 440 450 460 470 480 DYDLEDGVVR FYDYCNDKMK DGYFYIDIEG YLIPDEDAVY EFGISVFGTA LLFIDDVLLI 490 500 510 520 530 540 DNKTKQTPTN HTFEFGTIEE RNSIYLKKGR KYNVRVEYGS AATYTLSTNL SPSTGGRYSI 550 560 570 580 590 600 GCVKVIDPET EIDYAVRVAK SVDCVILCVG LTAEWETEGE DRKTMTLPSL SDKLVYSILQ 610 620 630 640 650 660 SNPNTVVVTQ SGTPIEMPWI SEAHTLLHIW YNGNELGNAL ANIIFGEQNP CGKLPITFPK 670 680 690 700 710 720 KLKDNPAYLS FRSSRGHCVY GEDVFVGYKY YEAVEREVLF PFGYGLSYTT FELSNLYLKN 730 740 750 760 770 780 CGERLRIDLE ISNTGPMSGA EIIQVYISQI VRSVNRPVKE LKEFSKVVLC PKETKLIRIE 790 800 810 820 830 LDIKYATSFY DELNEKWCSE EGEYNVLVGT SSKDIALTGK FTLPKTIHWT GL

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

[2]

"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed: 16823372] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329671 Genomic DNA. Translation: CAB91166.1.
RefSeq	NP_595060.1. NM_001020966.1.
3D structure databases
ProteinModelPortal	Q9P6J6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9P6J6.
Protein family/group databases
CAZy	GH3. Glycoside Hydrolase Family 3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPBC1683.04.1; SPBC1683.04.1:pep; SPBC1683.04.
GeneID	2540167.
KEGG	spo:SPBC1683.04.
NMPDR	fig|4896.1.peg.926.
Organism-specific databases
GeneDB_Spombe	SPBC1683.04.
Phylogenomic databases
eggNOG	fuNOG06351.
GeneTree	EFGT00050000000682.
HOGENOM	HBG749096.
OMA	KEWGWDG.
OrthoDB	EOG4VX5DC.
Gene expression databases
ArrayExpress	Q9P6J6.
Family and domain databases
InterPro	IPR019800. Glyco_hydro_3_AS. IPR002772. Glyco_hydro_3_C. IPR001764. Glyco_hydro_3_N. IPR017853. Glycoside_hydrolase_SF. IPR011658. PA14. [Graphical view]
Gene3D	G3DSA:3.40.50.1700. G3DSA:3.40.50.1700. 2 hits. G3DSA:3.20.20.300. Glyco_hydro_3_N. 1 hit.
KO	K05349.
Pfam	PF00933. Glyco_hydro_3. 1 hit. PF01915. Glyco_hydro_3_C. 1 hit. PF07691. PA14. 1 hit. [Graphical view]
PRINTS	PR00133. GLHYDRLASE3.
SMART	SM00758. PA14. 1 hit. [Graphical view]
SUPFAM	SSF52279. Glyco_hydro_3_C. 1 hit. SSF51445. Glyco_hydro_cat. 1 hit.
PROSITE	PS00775. GLYCOSYL_HYDROL_F3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

BGLS_SCHPO

Accession

Primary (citable) accession number: Q9P6J6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 10, 2009
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program