Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9P6J3 (MALT_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alpha-glucosidase

EC=3.2.1.20
Alternative name(s):
Maltase
Gene names
Name:mal1
ORF Names:SPBC1683.07
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length579 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.

Induction

Repressed by glucose and inositol.

Sequence similarities

Belongs to the glycosyl hydrolase 13 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 579579Alpha-glucosidase
PRO_0000310319

Sites

Active site2121Nucleophile By similarity
Active site2691Proton donor By similarity
Site3461Transition state stabilizer By similarity

Experimental info

Sequence conflict3811F → L in AAY57566. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9P6J3 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 7B79064326E445AA

FASTA57967,752
        10         20         30         40         50         60 
MKVVPSEKIK PNWWRETSVY QIYPASFKDS NGDGFGDLEG IISKVDYLKA LNVESIWLCP 

        70         80         90        100        110        120 
IYPSPLKDMG YDVSDYKQID SRYGTLEDLD RLMKALHERD MKLVMDLVLN HTSDQHEWFK 

       130        140        150        160        170        180 
ESRSSKTNPK RDWYFWKPAR YNEKGERLPP NNWRSYFDTS AWEWDEATQE YYLHLWSVGQ 

       190        200        210        220        230        240 
PDLNWETPKV REAVHDILRF WLDRGVDGFR LDAINMISKD QRFLDAPITD DRYEYQLAYQ 

       250        260        270        280        290        300 
YYANGPRIHE YLNGIGNILT EYDAFSVGEM PYVLDTNEIL HVVGADRREL TMIFQFDFVD 

       310        320        330        340        350        360 
LDLDPNQHKY IEGSWELSDL KKSLKKWQSA LLSGGGWNAS FIENHDQTRT VSRYLSDSPK 

       370        380        390        400        410        420 
YRAYSSKLMA LFIIFQSGTP FVFQGQELAL ANIPRDWPID EYLDVETQNF WKLFMSGNPS 

       430        440        450        460        470        480 
QEEIEKTMDI VNKRARDNGR TPMHWDSSPN GGFTKAGVKP WMRVTNDYKE WNAANQVNDP 

       490        500        510        520        530        540 
ESPYTFWSKA LELRKELKDA VVYGSFELIS EEDPSIVAFV RESSTYKLII LLNFTGNKVS 

       550        560        570 
YDCPLNLTSY EILLDNYKDF ICMTSPVTLN PYQAVLLKL 

« Hide

References

« Hide 'large scale' references
[1]"Regulation of MAL1+ gene expression encoding maltase in Schizosaccharomyces pombe by added inositol."
Yao S., Chi Z., He S.
Indian J. Biochem. Biophys. 43:143-147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], REPRESSION BY GLUCOSE AND INOSITOL.
[2]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ019991 Genomic DNA. Translation: AAY57566.1.
CU329671 Genomic DNA. Translation: CAB91169.1.
RefSeqNP_595063.1. NM_001020969.2.

3D structure databases

ProteinModelPortalQ9P6J3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid276520. 8 interactions.
MINTMINT-4704100.
STRING4896.SPBC1683.07-1.

Protein family/group databases

CAZyGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC1683.07.1; SPBC1683.07.1:pep; SPBC1683.07.
GeneID2539976.
KEGGspo:SPBC1683.07.

Organism-specific databases

PomBaseSPBC1683.07.

Phylogenomic databases

eggNOGCOG0366.
HOGENOMHOG000220641.
KOK01187.
OMATSADHTW.
OrthoDBEOG7M3J7X.
PhylomeDBQ9P6J3.

Family and domain databases

Gene3D2.60.40.1180. 1 hit.
3.20.20.80. 2 hits.
InterProIPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
[Graphical view]
SMARTSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Other

NextBio20801119.
PROQ9P6J3.

Entry information

Entry nameMALT_SCHPO
AccessionPrimary (citable) accession number: Q9P6J3
Secondary accession number(s): Q4U125
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries