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Protein

Guanylate kinase

Gene

SPBC1198.05

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.

Catalytic activityi

ATP + GMP = ADP + GDP.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi25 – 32ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinase (EC:2.7.4.8)
Alternative name(s):
GMP kinase
Gene namesi
ORF Names:SPBC1198.05
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1198.05
PomBaseiSPBC1198.05

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001706541 – 202Guanylate kinaseAdd BLAST202

Proteomic databases

MaxQBiQ9P6I5
PaxDbiQ9P6I5
PRIDEiQ9P6I5

PTM databases

iPTMnetiQ9P6I5

Interactioni

Protein-protein interaction databases

STRINGi4896.SPBC1198.05.1

Structurei

3D structure databases

ProteinModelPortaliQ9P6I5
SMRiQ9P6I5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 200Guanylate kinase-likePROSITE-ProRule annotationAdd BLAST183

Sequence similaritiesi

Belongs to the guanylate kinase family.Curated

Phylogenomic databases

HOGENOMiHOG000037640
InParanoidiQ9P6I5
KOiK00942
OMAiAGNYYGT
OrthoDBiEOG092C4CZ3
PhylomeDBiQ9P6I5

Family and domain databases

InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9P6I5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPQLSSSVA SKLVTLKLKP VVVFGPSGVG KSTLLKRLLK DHGDKLGFSV
60 70 80 90 100
SHTTRTPRAG EKDGIDYHFV TKEEFQKLVA EEKFVEWAVF SGNMYGTSIM
110 120 130 140 150
AIQELEAVNK KAILDIDLQG VLQVKASPID AQYVFLAPPS IEQLEVRLRG
160 170 180 190 200
RGTENESAIL QRLERARAEI EYSEKPGNFD ALIVNDDVEK AYKQLEAICL

SD
Length:202
Mass (Da):22,395
Last modified:October 1, 2000 - v1
Checksum:i4A395B71FDCCAF92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAB91180.1
RefSeqiNP_595074.1, NM_001020980.2

Genome annotation databases

EnsemblFungiiSPBC1198.05.1; SPBC1198.05.1:pep; SPBC1198.05
GeneIDi2539674
KEGGispo:SPBC1198.05

Similar proteinsi

Entry informationi

Entry nameiKGUA_SCHPO
AccessioniPrimary (citable) accession number: Q9P6I5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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