Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Guanylate kinase

Gene

SPBC1198.05

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.

Catalytic activityi

ATP + GMP = ADP + GDP.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi25 – 32ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-499943. Interconversion of nucleotide di- and triphosphates.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinase (EC:2.7.4.8)
Alternative name(s):
GMP kinase
Gene namesi
ORF Names:SPBC1198.05
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1198.05.
PomBaseiSPBC1198.05.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001706541 – 202Guanylate kinaseAdd BLAST202

Proteomic databases

MaxQBiQ9P6I5.
PRIDEiQ9P6I5.

Structurei

3D structure databases

ProteinModelPortaliQ9P6I5.
SMRiQ9P6I5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 200Guanylate kinase-likePROSITE-ProRule annotationAdd BLAST183

Sequence similaritiesi

Belongs to the guanylate kinase family.Curated

Phylogenomic databases

HOGENOMiHOG000037640.
InParanoidiQ9P6I5.
KOiK00942.
OMAiYGTLKSE.
OrthoDBiEOG092C4CZ3.
PhylomeDBiQ9P6I5.

Family and domain databases

InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9P6I5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPQLSSSVA SKLVTLKLKP VVVFGPSGVG KSTLLKRLLK DHGDKLGFSV
60 70 80 90 100
SHTTRTPRAG EKDGIDYHFV TKEEFQKLVA EEKFVEWAVF SGNMYGTSIM
110 120 130 140 150
AIQELEAVNK KAILDIDLQG VLQVKASPID AQYVFLAPPS IEQLEVRLRG
160 170 180 190 200
RGTENESAIL QRLERARAEI EYSEKPGNFD ALIVNDDVEK AYKQLEAICL

SD
Length:202
Mass (Da):22,395
Last modified:October 1, 2000 - v1
Checksum:i4A395B71FDCCAF92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB91180.1.
RefSeqiNP_595074.1. NM_001020980.2.

Genome annotation databases

EnsemblFungiiSPBC1198.05.1; SPBC1198.05.1:pep; SPBC1198.05.
GeneIDi2539674.
KEGGispo:SPBC1198.05.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB91180.1.
RefSeqiNP_595074.1. NM_001020980.2.

3D structure databases

ProteinModelPortaliQ9P6I5.
SMRiQ9P6I5.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ9P6I5.
PRIDEiQ9P6I5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC1198.05.1; SPBC1198.05.1:pep; SPBC1198.05.
GeneIDi2539674.
KEGGispo:SPBC1198.05.

Organism-specific databases

EuPathDBiFungiDB:SPBC1198.05.
PomBaseiSPBC1198.05.

Phylogenomic databases

HOGENOMiHOG000037640.
InParanoidiQ9P6I5.
KOiK00942.
OMAiYGTLKSE.
OrthoDBiEOG092C4CZ3.
PhylomeDBiQ9P6I5.

Enzyme and pathway databases

ReactomeiR-SPO-499943. Interconversion of nucleotide di- and triphosphates.

Miscellaneous databases

PROiPR:Q9P6I5.

Family and domain databases

InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKGUA_SCHPO
AccessioniPrimary (citable) accession number: Q9P6I5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: June 7, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.