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Protein

Putative mannan endo-1,6-alpha-mannosidase C1198.07c

Gene

SPBC1198.07c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH76. Glycoside Hydrolase Family 76.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative mannan endo-1,6-alpha-mannosidase C1198.07c (EC:3.2.1.101)
Alternative name(s):
Endo-alpha-1->6-D-mannanase C1198.07c
Gene namesi
ORF Names:SPBC1198.07c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1198.07c.
PomBaseiSPBC1198.07c.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini20 – 421LumenalSequence analysisAdd BLAST402
Transmembranei422 – 442HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000001213020 – 442Putative mannan endo-1,6-alpha-mannosidase C1198.07cAdd BLAST423

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi75N-linked (GlcNAc...)Sequence analysis1
Glycosylationi124N-linked (GlcNAc...)Sequence analysis1
Glycosylationi193N-linked (GlcNAc...)Sequence analysis1
Glycosylationi229N-linked (GlcNAc...)Sequence analysis1
Glycosylationi254N-linked (GlcNAc...)Sequence analysis1
Glycosylationi257N-linked (GlcNAc...)Sequence analysis1
Glycosylationi356N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ9P6I3.
PRIDEiQ9P6I3.

Interactioni

Protein-protein interaction databases

MINTiMINT-4704014.

Structurei

3D structure databases

ProteinModelPortaliQ9P6I3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 76 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000178818.
InParanoidiQ9P6I3.
KOiK08257.
OMAiALETIMS.
OrthoDBiEOG092C22S6.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR005198. Glyco_hydro_76.
IPR014480. Mannan-1_6-alpha_mannosidase.
[Graphical view]
PfamiPF03663. Glyco_hydro_76. 1 hit.
[Graphical view]
PIRSFiPIRSF016302. Man_a_manosd. 1 hit.
SUPFAMiSSF48208. SSF48208. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9P6I3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYLSFFFEF FFLFSFAFAF DFDVTSDDSI NSALTTVTDG MLNYYQSTSH
60 70 80 90 100
TFTAYWWMTG AGLNSMTDTY AATGNTTHLD MLISALVANK GDNNDYAPNS
110 120 130 140 150
EKFDLGNDDQ GIWGLSAMSA AEVNMTTGDS SASFTELAQA VFNEIMSRWD
160 170 180 190 200
TSSCGGGVRW QIYSFNNGYS YKNSISNGIL FQLAARLARY TNNDTYVDLA
210 220 230 240 250
QKVWDWSTTV GFVDLDDYTV YDGASVTSNC SSITNEQWSY NVGVYLAGTA
260 270 280 290 300
FLYNYTNGSS VWQTHMEGLM NKALDYYFTS DKIIYEPSCE PTESCNSDQT
310 320 330 340 350
AFKGMLARFL GYTMQLAPYT VETILPYIQS SAEAAALACS GGSDGVTCGY
360 370 380 390 400
MWYWNNGTWD DHYGLGEQIS AVETFQALLA QQSATILTLD TGASSESNPD
410 420 430 440
AGTDDGDTVT ITPATKSDKG WAGFLTFAFS FVFLLFSIWL YF
Length:442
Mass (Da):48,877
Last modified:July 11, 2012 - v2
Checksum:iE5D2F9EEAFCF749A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB91182.2.
RefSeqiNP_595076.2. NM_001020982.2.

Genome annotation databases

EnsemblFungiiSPBC1198.07c.1; SPBC1198.07c.1:pep; SPBC1198.07c.
GeneIDi2539836.
KEGGispo:SPBC1198.07c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAB91182.2.
RefSeqiNP_595076.2. NM_001020982.2.

3D structure databases

ProteinModelPortaliQ9P6I3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4704014.

Protein family/group databases

CAZyiGH76. Glycoside Hydrolase Family 76.

Proteomic databases

MaxQBiQ9P6I3.
PRIDEiQ9P6I3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC1198.07c.1; SPBC1198.07c.1:pep; SPBC1198.07c.
GeneIDi2539836.
KEGGispo:SPBC1198.07c.

Organism-specific databases

EuPathDBiFungiDB:SPBC1198.07c.
PomBaseiSPBC1198.07c.

Phylogenomic databases

HOGENOMiHOG000178818.
InParanoidiQ9P6I3.
KOiK08257.
OMAiALETIMS.
OrthoDBiEOG092C22S6.

Miscellaneous databases

PROiQ9P6I3.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR005198. Glyco_hydro_76.
IPR014480. Mannan-1_6-alpha_mannosidase.
[Graphical view]
PfamiPF03663. Glyco_hydro_76. 1 hit.
[Graphical view]
PIRSFiPIRSF016302. Man_a_manosd. 1 hit.
SUPFAMiSSF48208. SSF48208. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYHG7_SCHPO
AccessioniPrimary (citable) accession number: Q9P6I3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: July 11, 2012
Last modified: November 30, 2016
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.