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Protein

Ubiquitin-conjugating enzyme E2 16

Gene

ubc16

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the covalent attachment of ubiquitin to other proteins.PROSITE-ProRule annotation

Catalytic activityi

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei90Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-conjugating enzyme E2 16 (EC:2.3.2.23)
Alternative name(s):
E2 ubiquitin-conjugating enzyme 16
Ubiquitin carrier protein 16
Ubiquitin-protein ligase 16
Gene namesi
Name:ubc16
ORF Names:SPBC1198.09
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1198.09
PomBaseiSPBC1198.09 ubc16

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000825901 – 160Ubiquitin-conjugating enzyme E2 16Add BLAST160

Proteomic databases

MaxQBiQ9P6I1
PaxDbiQ9P6I1
PRIDEiQ9P6I1

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi276505, 20 interactors
STRINGi4896.SPBC1198.09.1

Structurei

3D structure databases

ProteinModelPortaliQ9P6I1
SMRiQ9P6I1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000233455
InParanoidiQ9P6I1
KOiK10689
OMAiCVRAVRM
OrthoDBiEOG092C50OL
PhylomeDBiQ9P6I1

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9P6I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSSIKRLHK EYASFQAGDI SGLLLLKPVT DVDMFHWKAV IEGPTETPYE
60 70 80 90 100
GGQWVLDIHV HEGYPISPPS VYFQTKIVHP NISWTNGEVC MDILKTHWSP
110 120 130 140 150
AWSLQSACLA IISLLSNYDA SSPLNVDAAK LLRTGDKTAY NSLVRCTTYL
160
YAKGKIEDLS
Length:160
Mass (Da):17,842
Last modified:March 1, 2001 - v2
Checksum:iD1A5CCC383CE832C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAB91184.2
RefSeqiNP_595078.1, NM_001020984.2

Genome annotation databases

EnsemblFungiiSPBC1198.09.1; SPBC1198.09.1:pep; SPBC1198.09
GeneIDi2539961
KEGGispo:SPBC1198.09

Similar proteinsi

Entry informationi

Entry nameiUBC16_SCHPO
AccessioniPrimary (citable) accession number: Q9P6I1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: March 1, 2001
Last modified: March 28, 2018
This is version 119 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

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