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Q9P4W1

- COX8_SCHPO

UniProt

Q9P4W1 - COX8_SCHPO

Protein

Cytochrome c oxidase polypeptide VIII, mitochondrial

Gene

cox8

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic respiration Source: PomBase
    2. hydrogen ion transmembrane transport Source: GOC

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase polypeptide VIII, mitochondrial (EC:1.9.3.1)
    Gene namesi
    Name:cox8
    ORF Names:SPAC24C9.16c
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome I

    Organism-specific databases

    PomBaseiSPAC24C9.16c.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial respiratory chain complex IV Source: PomBase
    2. mitochondrion Source: PomBase

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini? – 66Cytochrome c oxidase polypeptide VIII, mitochondrialPRO_0000006172
    Transit peptidei1 – ?MitochondrionSequence Analysis

    Proteomic databases

    MaxQBiQ9P4W1.

    Interactioni

    Subunit structurei

    Composed of at least 11 subunits.By similarity

    Protein-protein interaction databases

    BioGridi279098. 6 interactions.
    MINTiMINT-4703879.
    STRINGi4896.SPAC24C9.16c-1.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cytochrome c oxidase VIIc family.Curated

    Keywords - Domaini

    Transit peptide

    Phylogenomic databases

    KOiK02272.

    Family and domain databases

    Gene3Di4.10.49.10. 1 hit.
    InterProiIPR004202. COX7C/Cox8.
    [Graphical view]
    PfamiPF02935. COX7C. 1 hit.
    [Graphical view]
    SUPFAMiSSF81427. SSF81427. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9P4W1-1 [UniParc]FASTAAdd to Basket

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    MLRYSLQARS ALRGVRFSSS HSAPKPGSTI PFYINKKPLP TLLYFGTFGV   50
    IFSIPFIVVK YHNRNL 66
    Length:66
    Mass (Da):7,502
    Last modified:October 1, 2000 - v1
    Checksum:iE6E6559AF6E3D287
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB71272.1.
    RefSeqiNP_594028.1. NM_001019453.2.

    Genome annotation databases

    EnsemblFungiiSPAC24C9.16c.1; SPAC24C9.16c.1:pep; SPAC24C9.16c.
    GeneIDi2542644.
    KEGGispo:SPAC24C9.16c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329670 Genomic DNA. Translation: CAB71272.1 .
    RefSeqi NP_594028.1. NM_001019453.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 279098. 6 interactions.
    MINTi MINT-4703879.
    STRINGi 4896.SPAC24C9.16c-1.

    Proteomic databases

    MaxQBi Q9P4W1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPAC24C9.16c.1 ; SPAC24C9.16c.1:pep ; SPAC24C9.16c .
    GeneIDi 2542644.
    KEGGi spo:SPAC24C9.16c.

    Organism-specific databases

    PomBasei SPAC24C9.16c.

    Phylogenomic databases

    KOi K02272.

    Miscellaneous databases

    NextBioi 20803693.

    Family and domain databases

    Gene3Di 4.10.49.10. 1 hit.
    InterProi IPR004202. COX7C/Cox8.
    [Graphical view ]
    Pfami PF02935. COX7C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81427. SSF81427. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.

    Entry informationi

    Entry nameiCOX8_SCHPO
    AccessioniPrimary (citable) accession number: Q9P4W1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 7, 2004
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3