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Protein

Cytochrome c oxidase polypeptide VIII, mitochondrial

Gene

cox8

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase polypeptide VIII, mitochondrial (EC:1.9.3.1)
Gene namesi
Name:cox8
ORF Names:SPAC24C9.16c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC24C9.16c.
PomBaseiSPAC24C9.16c. cox8.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial respiratory chain complex IV Source: PomBase
  • mitochondrion Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000006172? – 66Cytochrome c oxidase polypeptide VIII, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiQ9P4W1.
PRIDEiQ9P4W1.

Interactioni

Subunit structurei

Composed of at least 11 subunits.By similarity

Protein-protein interaction databases

BioGridi279098. 6 interactors.
MINTiMINT-4703879.

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c oxidase VIIc family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

KOiK02272.
OrthoDBiEOG092C5XSY.

Family and domain databases

CDDicd00929. Cyt_c_Oxidase_VIIc. 1 hit.
Gene3Di4.10.49.10. 1 hit.
InterProiIPR004202. COX7C/Cox8.
[Graphical view]
PANTHERiPTHR13313. PTHR13313. 1 hit.
PfamiPF02935. COX7C. 1 hit.
[Graphical view]
SUPFAMiSSF81427. SSF81427. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9P4W1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRYSLQARS ALRGVRFSSS HSAPKPGSTI PFYINKKPLP TLLYFGTFGV
60
IFSIPFIVVK YHNRNL
Length:66
Mass (Da):7,502
Last modified:October 1, 2000 - v1
Checksum:iE6E6559AF6E3D287
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB71272.1.
RefSeqiNP_594028.1. NM_001019453.2.

Genome annotation databases

EnsemblFungiiSPAC24C9.16c.1; SPAC24C9.16c.1:pep; SPAC24C9.16c.
GeneIDi2542644.
KEGGispo:SPAC24C9.16c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB71272.1.
RefSeqiNP_594028.1. NM_001019453.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279098. 6 interactors.
MINTiMINT-4703879.

Proteomic databases

MaxQBiQ9P4W1.
PRIDEiQ9P4W1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC24C9.16c.1; SPAC24C9.16c.1:pep; SPAC24C9.16c.
GeneIDi2542644.
KEGGispo:SPAC24C9.16c.

Organism-specific databases

EuPathDBiFungiDB:SPAC24C9.16c.
PomBaseiSPAC24C9.16c. cox8.

Phylogenomic databases

KOiK02272.
OrthoDBiEOG092C5XSY.

Miscellaneous databases

PROiQ9P4W1.

Family and domain databases

CDDicd00929. Cyt_c_Oxidase_VIIc. 1 hit.
Gene3Di4.10.49.10. 1 hit.
InterProiIPR004202. COX7C/Cox8.
[Graphical view]
PANTHERiPTHR13313. PTHR13313. 1 hit.
PfamiPF02935. COX7C. 1 hit.
[Graphical view]
SUPFAMiSSF81427. SSF81427. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCOX8_SCHPO
AccessioniPrimary (citable) accession number: Q9P4W1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.