Reviewed,
UniProtKB/Swiss-Prot Q9P4T7 (TYSY_AGABI)
Last modified
June 16, 2009.
Version 40.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Thymidylate synthase Short name=TSase Short name=TS EC=2.1.1.45 | ||
| Gene names |
| ||
| Organism | Agaricus bisporus (Common mushroom) | ||
| Taxonomic identifier | 5341 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Homobasidiomycetes › Agaricomycetidae › Agaricales › Agaricaceae › Agaricus |
Protein attributes
| Sequence length | 296 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP. |
| Pathway | |
| Subunit structure | Homodimer By similarity. |
| Sequence similarities | Belongs to the thymidylate synthase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Nucleotide biosynthesis |
| Molecular function | Methyltransferase Transferase |
| Gene Ontology (GO) | |
| Biological process | dTMP biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Molecular function | thymidylate synthase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| [1] | "Genomic sequencing of superoxide dismutase in Agaricus bisporus." Eastwood D.C., Bains N.K., Henderson J., Burton K.S. Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Horst U3. |
Cross-references
Sequence databases | |
|---|---|
| AJ401221 Genomic DNA. Translation: CAB96042.1. | |
3D structure databases | |
| HSSP | HSSP built from PDB template 1HW4 based on UniProtKB P04818. |
| ModBase | Search... |
Enzyme and pathway databases | |
| BRENDA | 2.1.1.45. 984. |
Family and domain databases | |
| InterPro | IPR000398. Thymidylat_synth_C. [Graphical view] |
| Gene3D | G3DSA:3.30.572.10. Thymidylat_synth_C. 1 hit. |
| PANTHER | PTHR11549:SF2. Thymidylat_synth_C. 1 hit. |
| Pfam | PF00303. Thymidylat_synt. 1 hit. [Graphical view] |
| PRINTS | PR00108. THYMDSNTHASE. |
| ProDom | PD001180. Thymidylat_synth. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR03284. thym_sym. 1 hit. |
| PROSITE | PS00091. THYMIDYLATE_SYNTHASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TYSY_AGABI | ||||||||
| Accession | Primary (citable) accession number: Q9P4T7 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


