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Protein

Probable high-affinity hexose transporter ght8, mitochondrial

Gene

ght8

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • glucose import Source: GO_Central
  • hexose transmembrane transport Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Probable high-affinity hexose transporter ght8, mitochondrial
Short name:
Hexose transporter 8
Gene namesi
Name:ght8
ORF Names:SPCC548.06c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC548.06c.
PomBaseiSPCC548.06c. ght8.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini22 – 8665Mitochondrial intermembraneSequence analysisAdd
BLAST
Transmembranei87 – 10721HelicalSequence analysisAdd
BLAST
Topological domaini108 – 1125CytoplasmicSequence analysis
Transmembranei113 – 13321HelicalSequence analysisAdd
BLAST
Topological domaini134 – 14411Mitochondrial intermembraneSequence analysisAdd
BLAST
Transmembranei145 – 16521HelicalSequence analysisAdd
BLAST
Topological domaini166 – 17914CytoplasmicSequence analysisAdd
BLAST
Transmembranei180 – 20021HelicalSequence analysisAdd
BLAST
Topological domaini201 – 304104Mitochondrial intermembraneSequence analysisAdd
BLAST
Transmembranei305 – 32521HelicalSequence analysisAdd
BLAST
Topological domaini326 – 3283CytoplasmicSequence analysis
Transmembranei329 – 34921HelicalSequence analysisAdd
BLAST
Topological domaini350 – 36314Mitochondrial intermembraneSequence analysisAdd
BLAST
Transmembranei364 – 38421HelicalSequence analysisAdd
BLAST
Topological domaini385 – 40420CytoplasmicSequence analysisAdd
BLAST
Transmembranei405 – 42521HelicalSequence analysisAdd
BLAST
Topological domaini426 – 4327Mitochondrial intermembraneSequence analysis
Transmembranei433 – 45321HelicalSequence analysisAdd
BLAST
Topological domaini454 – 54794CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of plasma membrane Source: PomBase
  • mitochondrial membrane Source: UniProtKB-SubCell
  • plasma membrane Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2121MitochondrionSequence analysisAdd
BLAST
Chaini22 – 547526Probable high-affinity hexose transporter ght8, mitochondrialPRO_0000310744Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei519 – 5191Phosphoserine1 Publication
Modified residuei523 – 5231Phosphothreonine1 Publication
Modified residuei526 – 5261Phosphothreonine1 Publication
Modified residuei527 – 5271Phosphoserine1 Publication
Modified residuei528 – 5281Phosphoserine1 Publication
Modified residuei529 – 5291Phosphoserine1 Publication
Modified residuei537 – 5371Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9P3U7.

PTM databases

iPTMnetiQ9P3U7.

Interactioni

Protein-protein interaction databases

MINTiMINT-4703758.

Structurei

3D structure databases

ProteinModelPortaliQ9P3U7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000202870.
InParanoidiQ9P3U7.
KOiK08139.
OrthoDBiEOG73JM4H.
PhylomeDBiQ9P3U7.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9P3U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKTLTIVML VFVSMAGWMF GADTGSIGGI TNMRDFQSRF ADRYNPVTDT
60 70 80 90 100
YSYSSARQGL ITGMVNVGSM TGCILSSPLM DRIGKRVSIM FWTIVYLIGI
110 120 130 140 150
ILQVTAVPSW VQIMVAKIWT GLAIGALSVL APGFQSEVAP ATLRGTIVTT
160 170 180 190 200
YQLAVTGGIF IAACINMGTH KLHKTAQWRV SMGINLLWGI IMFIGISFLP
210 220 230 240 250
ESPRYLIAIG KDEEALDIMC KNNVLPREHE IIQTEYHVIK TDCEAEMAGG
260 270 280 290 300
PATWGDILGA DIRYRTFLGL GVMSLQQLTG DNYYFYYGFE VFEGTGMNSP
310 320 330 340 350
YLSALILDAV NFGCTFGGLF VLEFFGRRMP LIIGGVWQSI TFFIYAAVGN
360 370 380 390 400
RALTRKNGTS NHRAGAVMIV FSCLFIFSFA QTWGPAAYVI VGESYPIRYR
410 420 430 440 450
SKCAAVATTG NWLWGFLITF FTPFISDSIG FKYGYIFAAC NLCAACIIFL
460 470 480 490 500
FAHETKGLTL EEINELYLSG AKPWMPRPEN LGQAAKQQQE VLEKSRGVQG
510 520 530 540
ESAAHLENVD NEGMEDTSSN DITSSTSSSE GRAKPESNYV DEQDRYA
Length:547
Mass (Da):60,176
Last modified:October 1, 2000 - v1
Checksum:iFE157E411E575075
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB94948.1.
RefSeqiNP_587746.1. NM_001022740.2.

Genome annotation databases

EnsemblFungiiSPCC548.06c.1; SPCC548.06c.1:pep; SPCC548.06c.
GeneIDi2539300.
KEGGispo:SPCC548.06c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA. Translation: CAB94948.1.
RefSeqiNP_587746.1. NM_001022740.2.

3D structure databases

ProteinModelPortaliQ9P3U7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4703758.

PTM databases

iPTMnetiQ9P3U7.

Proteomic databases

MaxQBiQ9P3U7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPCC548.06c.1; SPCC548.06c.1:pep; SPCC548.06c.
GeneIDi2539300.
KEGGispo:SPCC548.06c.

Organism-specific databases

EuPathDBiFungiDB:SPCC548.06c.
PomBaseiSPCC548.06c. ght8.

Phylogenomic databases

HOGENOMiHOG000202870.
InParanoidiQ9P3U7.
KOiK08139.
OrthoDBiEOG73JM4H.
PhylomeDBiQ9P3U7.

Miscellaneous databases

PROiQ9P3U7.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR005828. MFS_sugar_transport_like.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamiPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSiPR00171. SUGRTRNSPORT.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00879. SP. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-519; THR-523; THR-526; SER-527; SER-528; SER-529 AND SER-537, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiGHT8_SCHPO
AccessioniPrimary (citable) accession number: Q9P3U7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2000
Last modified: July 6, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.