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Protein

Probable high-affinity hexose transporter ght8, mitochondrial

Gene

ght8

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Probable high-affinity hexose transporter ght8, mitochondrial
Short name:
Hexose transporter 8
Gene namesi
Name:ght8
ORF Names:SPCC548.06c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC548.06c
PomBaseiSPCC548.06c ght8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini22 – 86Mitochondrial intermembraneSequence analysisAdd BLAST65
Transmembranei87 – 107HelicalSequence analysisAdd BLAST21
Topological domaini108 – 112CytoplasmicSequence analysis5
Transmembranei113 – 133HelicalSequence analysisAdd BLAST21
Topological domaini134 – 144Mitochondrial intermembraneSequence analysisAdd BLAST11
Transmembranei145 – 165HelicalSequence analysisAdd BLAST21
Topological domaini166 – 179CytoplasmicSequence analysisAdd BLAST14
Transmembranei180 – 200HelicalSequence analysisAdd BLAST21
Topological domaini201 – 304Mitochondrial intermembraneSequence analysisAdd BLAST104
Transmembranei305 – 325HelicalSequence analysisAdd BLAST21
Topological domaini326 – 328CytoplasmicSequence analysis3
Transmembranei329 – 349HelicalSequence analysisAdd BLAST21
Topological domaini350 – 363Mitochondrial intermembraneSequence analysisAdd BLAST14
Transmembranei364 – 384HelicalSequence analysisAdd BLAST21
Topological domaini385 – 404CytoplasmicSequence analysisAdd BLAST20
Transmembranei405 – 425HelicalSequence analysisAdd BLAST21
Topological domaini426 – 432Mitochondrial intermembraneSequence analysis7
Transmembranei433 – 453HelicalSequence analysisAdd BLAST21
Topological domaini454 – 547CytoplasmicSequence analysisAdd BLAST94

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 21MitochondrionSequence analysisAdd BLAST21
ChainiPRO_000031074422 – 547Probable high-affinity hexose transporter ght8, mitochondrialAdd BLAST526

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei519Phosphoserine1 Publication1
Modified residuei523Phosphothreonine1 Publication1
Modified residuei526Phosphothreonine1 Publication1
Modified residuei527Phosphoserine1 Publication1
Modified residuei528Phosphoserine1 Publication1
Modified residuei529Phosphoserine1 Publication1
Modified residuei537Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9P3U7
PaxDbiQ9P3U7
PRIDEiQ9P3U7

PTM databases

iPTMnetiQ9P3U7

Interactioni

Protein-protein interaction databases

STRINGi4896.SPCC548.06c.1

Structurei

3D structure databases

ProteinModelPortaliQ9P3U7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000202870
InParanoidiQ9P3U7
KOiK08139
OMAiQMSAGAY
OrthoDBiEOG092C1Q5W
PhylomeDBiQ9P3U7

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00879 SP, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00216 SUGAR_TRANSPORT_1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9P3U7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKTLTIVML VFVSMAGWMF GADTGSIGGI TNMRDFQSRF ADRYNPVTDT
60 70 80 90 100
YSYSSARQGL ITGMVNVGSM TGCILSSPLM DRIGKRVSIM FWTIVYLIGI
110 120 130 140 150
ILQVTAVPSW VQIMVAKIWT GLAIGALSVL APGFQSEVAP ATLRGTIVTT
160 170 180 190 200
YQLAVTGGIF IAACINMGTH KLHKTAQWRV SMGINLLWGI IMFIGISFLP
210 220 230 240 250
ESPRYLIAIG KDEEALDIMC KNNVLPREHE IIQTEYHVIK TDCEAEMAGG
260 270 280 290 300
PATWGDILGA DIRYRTFLGL GVMSLQQLTG DNYYFYYGFE VFEGTGMNSP
310 320 330 340 350
YLSALILDAV NFGCTFGGLF VLEFFGRRMP LIIGGVWQSI TFFIYAAVGN
360 370 380 390 400
RALTRKNGTS NHRAGAVMIV FSCLFIFSFA QTWGPAAYVI VGESYPIRYR
410 420 430 440 450
SKCAAVATTG NWLWGFLITF FTPFISDSIG FKYGYIFAAC NLCAACIIFL
460 470 480 490 500
FAHETKGLTL EEINELYLSG AKPWMPRPEN LGQAAKQQQE VLEKSRGVQG
510 520 530 540
ESAAHLENVD NEGMEDTSSN DITSSTSSSE GRAKPESNYV DEQDRYA
Length:547
Mass (Da):60,176
Last modified:October 1, 2000 - v1
Checksum:iFE157E411E575075
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAB94948.1
RefSeqiNP_587746.1, NM_001022740.2

Genome annotation databases

EnsemblFungiiSPCC548.06c.1; SPCC548.06c.1:pep; SPCC548.06c
GeneIDi2539300
KEGGispo:SPCC548.06c

Similar proteinsi

Entry informationi

Entry nameiGHT8_SCHPO
AccessioniPrimary (citable) accession number: Q9P3U7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health