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Protein

Probable mitochondrial 2-oxodicarboxylate carrier

Gene

SPAC328.09

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

ReactomeiR-SPO-71064. Lysine catabolism.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable mitochondrial 2-oxodicarboxylate carrier
Gene namesi
ORF Names:SPAC328.09
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC328.09.
PomBaseiSPAC328.09.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2621Helical; Name=1Sequence analysisAdd
BLAST
Transmembranei62 – 8120Helical; Name=2Sequence analysisAdd
BLAST
Transmembranei105 – 12521Helical; Name=3Sequence analysisAdd
BLAST
Transmembranei159 – 17921Helical; Name=4Sequence analysisAdd
BLAST
Transmembranei203 – 22321Helical; Name=5Sequence analysisAdd
BLAST
Transmembranei267 – 28721Helical; Name=6Sequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 298298Probable mitochondrial 2-oxodicarboxylate carrierPRO_0000310803Add
BLAST

Proteomic databases

MaxQBiQ9P3T7.

Structurei

3D structure databases

ProteinModelPortaliQ9P3T7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati6 – 9287Solcar 1Add
BLAST
Repeati102 – 18887Solcar 2Add
BLAST
Repeati197 – 28791Solcar 3Add
BLAST

Sequence similaritiesi

Contains 3 Solcar repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000168307.
InParanoidiQ9P3T7.
KOiK15110.
OMAiTINCLRT.
OrthoDBiEOG72ZCR5.
PhylomeDBiQ9P3T7.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P3T7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPHDNIPFPV TFAAGAVAGI SEVLTLYPLD VVKTRMQLSV GKSDYNGTFD
60 70 80 90 100
CLKKIVKNEG PHRLYRGILP PILMEAPKRA LKFASNDTYS KLWRKVFKRK
110 120 130 140 150
DSSPALSILT GSCAGFTETF VVVPFELMKI RLQDVKNASK YNGTVDCFTK
160 170 180 190 200
IVKQERILAL YNGFEATMWR HVVWNAGYFG VIQKIRNSLT PASSRIGEIR
210 220 230 240 250
NNLIAGTIGG IFGTFLSTPF DVIKSRIQTV PRIAGQVPKY NWAYPALVTV
260 270 280 290
AREEGFTALY KGFVPKVLRL GPGGGILLVV FNSVIEFYKR CLVHNASA
Length:298
Mass (Da):33,100
Last modified:October 1, 2000 - v1
Checksum:iD6ADC939BA1F6F9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB96004.1.
RefSeqiNP_594211.1. NM_001019634.2.

Genome annotation databases

EnsemblFungiiSPAC328.09.1; SPAC328.09.1:pep; SPAC328.09.
GeneIDi2543171.
KEGGispo:SPAC328.09.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB96004.1.
RefSeqiNP_594211.1. NM_001019634.2.

3D structure databases

ProteinModelPortaliQ9P3T7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiQ9P3T7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC328.09.1; SPAC328.09.1:pep; SPAC328.09.
GeneIDi2543171.
KEGGispo:SPAC328.09.

Organism-specific databases

EuPathDBiFungiDB:SPAC328.09.
PomBaseiSPAC328.09.

Phylogenomic databases

HOGENOMiHOG000168307.
InParanoidiQ9P3T7.
KOiK15110.
OMAiTINCLRT.
OrthoDBiEOG72ZCR5.
PhylomeDBiQ9P3T7.

Enzyme and pathway databases

ReactomeiR-SPO-71064. Lysine catabolism.

Miscellaneous databases

NextBioi20804197.
PROiQ9P3T7.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiIPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
[Graphical view]
PfamiPF00153. Mito_carr. 3 hits.
[Graphical view]
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiPS50920. SOLCAR. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiODC_SCHPO
AccessioniPrimary (citable) accession number: Q9P3T7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 1, 2000
Last modified: May 11, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.