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Protein

Probable peptide transporter ptr2

Gene

ptr2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Uptake of small peptides.By similarity

GO - Molecular functioni

  • dipeptide transmembrane transporter activity Source: PomBase
  • dipeptide transporter activity Source: PomBase
  • tripeptide transporter activity Source: PomBase

GO - Biological processi

  • dipeptide transmembrane transport Source: PomBase
  • protein transport Source: UniProtKB-KW
  • tripeptide transmembrane transport Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Peptide transport, Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-SPO-427975. Proton/oligopeptide cotransporters.
R-SPO-6798695. Neutrophil degranulation.

Protein family/group databases

TCDBi2.A.17.2.1. the proton-dependent oligopeptide transporter (pot/ptr) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable peptide transporter ptr2
Alternative name(s):
Peptide permease ptr2
Gene namesi
Name:ptr2
ORF Names:SPBC13A2.04c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC13A2.04c.
PomBaseiSPBC13A2.04c. ptr2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Transmembranei161 – 181HelicalSequence analysisAdd BLAST21
Transmembranei187 – 207HelicalSequence analysisAdd BLAST21
Transmembranei247 – 267HelicalSequence analysisAdd BLAST21
Transmembranei273 – 293HelicalSequence analysisAdd BLAST21
Transmembranei400 – 420HelicalSequence analysisAdd BLAST21
Transmembranei430 – 450HelicalSequence analysisAdd BLAST21
Transmembranei475 – 495HelicalSequence analysisAdd BLAST21
Transmembranei510 – 530HelicalSequence analysisAdd BLAST21
Transmembranei541 – 561HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • cell division site Source: PomBase
  • fungal-type vacuole Source: PomBase
  • integral component of plasma membrane Source: PomBase
  • plasma membrane of cell tip Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000643191 – 618Probable peptide transporter ptr2Add BLAST618

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei22Phosphoserine1 Publication1
Modified residuei23Phosphotyrosine1 Publication1
Modified residuei25Phosphoserine1 Publication1
Modified residuei33Phosphoserine1 Publication1
Modified residuei35Phosphothreonine1 Publication1
Modified residuei44Phosphoserine1 Publication1
Modified residuei45Phosphothreonine1 Publication1
Modified residuei51Phosphoserine1 Publication1
Modified residuei53Phosphoserine1 Publication1
Modified residuei54Phosphothreonine1 Publication1
Modified residuei594Phosphoserine1 Publication1
Modified residuei618Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9P380.
PRIDEiQ9P380.

PTM databases

iPTMnetiQ9P380.

Interactioni

Protein-protein interaction databases

BioGridi276734. 50 interactors.
MINTiMINT-4703586.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000161421.
InParanoidiQ9P380.
KOiK03305.
OrthoDBiEOG092C1LLP.
PhylomeDBiQ9P380.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR000109. POT_fam.
IPR018456. PTR2_symporter_CS.
[Graphical view]
PANTHERiPTHR11654. PTHR11654. 2 hits.
PfamiPF00854. PTR2. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS01022. PTR2_1. 1 hit.
PS01023. PTR2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P380-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSIEEQITK SDSDFIISED QSYLSKEKKA DGSATINTAD EQSSTDELQK
60 70 80 90 100
SMSTGVLVNG DLYPSPTEEE LATLPRVCGT IPWKAFIIII VELCERFAYY
110 120 130 140 150
GLTVPFQNYM QFGPKDATPG ALNLGESGAD GLSNFFTFWC YVTPVGAALI
160 170 180 190 200
ADQFLGRYNT IVCSAVIYFI GILILTCTAI PSVIDAGKSM GGFVVSLIII
210 220 230 240 250
GLGTGGIKSN VSPLMAEQLP KIPPYVKTKK NGSKVIVDPV VTTSRAYMIF
260 270 280 290 300
YWSINVGSLS VLATTSLEST KGFVYAYLLP LCVFVIPLII LAVSKRFYKH
310 320 330 340 350
TPPSGSIFVR VGQVFFLAAQ NKFNLEKTKP SCTTTVGRVT LKDQWDDLFI
360 370 380 390 400
DELKRALRAC KTFLFYPIYW VCYGQMTNNL ISQAGQMQTG NVSNDLFQAF
410 420 430 440 450
DSIALIIFIP ICDNIIYPLL RKYNIPFKPI LRITLGFMFA TASMIYAAVL
460 470 480 490 500
QAKIYQRGPC YANFTDTCVS NDISVWIQIP AYVLIAFSEI FASITGLEFA
510 520 530 540 550
FTKAPPSMKS IITALFLFTN AFGAILSICI SSTAVNPKLT WMYTGIAVTA
560 570 580 590 600
FIAGIMFWVC FHHYDAMEDE QNQLEFKRND ALTKKDVEKE VHDSYSMADE
610
SQYNLEKATA EEEIMKST
Length:618
Mass (Da):68,499
Last modified:October 1, 2000 - v1
Checksum:i33C10E3C63B98474
GO

Sequence cautioni

The sequence AAA53173 differs from that shown. Reason: Frameshift at positions 296 and 341.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti38T → Q in AAA53173 (PubMed:7919993).Curated1
Sequence conflicti76R → S in AAA53173 (PubMed:7919993).Curated1
Sequence conflicti127S → T in AAA53173 (PubMed:7919993).Curated1
Sequence conflicti253S → T in AAA53173 (PubMed:7919993).Curated1
Sequence conflicti609 – 610TA → NC (PubMed:7919993).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U01171 mRNA. Translation: AAA53173.1. Frameshift.
CU329671 Genomic DNA. Translation: CAB99397.1.
AB027874 Genomic DNA. Translation: BAA87178.1.
RefSeqiNP_596417.1. NM_001022336.2.

Genome annotation databases

EnsemblFungiiSPBC13A2.04c.1; SPBC13A2.04c.1:pep; SPBC13A2.04c.
GeneIDi2540201.
KEGGispo:SPBC13A2.04c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U01171 mRNA. Translation: AAA53173.1. Frameshift.
CU329671 Genomic DNA. Translation: CAB99397.1.
AB027874 Genomic DNA. Translation: BAA87178.1.
RefSeqiNP_596417.1. NM_001022336.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276734. 50 interactors.
MINTiMINT-4703586.

Protein family/group databases

TCDBi2.A.17.2.1. the proton-dependent oligopeptide transporter (pot/ptr) family.

PTM databases

iPTMnetiQ9P380.

Proteomic databases

MaxQBiQ9P380.
PRIDEiQ9P380.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC13A2.04c.1; SPBC13A2.04c.1:pep; SPBC13A2.04c.
GeneIDi2540201.
KEGGispo:SPBC13A2.04c.

Organism-specific databases

EuPathDBiFungiDB:SPBC13A2.04c.
PomBaseiSPBC13A2.04c. ptr2.

Phylogenomic databases

HOGENOMiHOG000161421.
InParanoidiQ9P380.
KOiK03305.
OrthoDBiEOG092C1LLP.
PhylomeDBiQ9P380.

Enzyme and pathway databases

ReactomeiR-SPO-427975. Proton/oligopeptide cotransporters.
R-SPO-6798695. Neutrophil degranulation.

Miscellaneous databases

PROiQ9P380.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR000109. POT_fam.
IPR018456. PTR2_symporter_CS.
[Graphical view]
PANTHERiPTHR11654. PTHR11654. 2 hits.
PfamiPF00854. PTR2. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS01022. PTR2_1. 1 hit.
PS01023. PTR2_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPTR2_SCHPO
AccessioniPrimary (citable) accession number: Q9P380
Secondary accession number(s): P46031, Q9UU13
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Was originally (PubMed:7919993) reported to be isolated from an A.thaliana cv. Landsberg erecta cDNA library.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.