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Q9P327 (PLB4_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative lysophospholipase C977.09c/C1348.10c

EC=3.1.1.5
Alternative name(s):
Phospholipase B
Gene names
ORF Names:SPAC977.09c
AND
ORF Names:SPBC1348.10c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length673 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the release of fatty acids from lysophospholipids By similarity.

Catalytic activity

2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.

Subcellular location

Secreted Probable.

Sequence similarities

Belongs to the lysophospholipase family.

Contains 1 PLA2c domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 673654Putative lysophospholipase C977.09c/C1348.10c
PRO_0000024642

Regions

Domain74 – 615542PLA2c

Amino acid modifications

Glycosylation721N-linked (GlcNAc...) Potential
Glycosylation1251N-linked (GlcNAc...) Potential
Glycosylation1911N-linked (GlcNAc...) Potential
Glycosylation1941N-linked (GlcNAc...) Potential
Glycosylation2721N-linked (GlcNAc...) Potential
Glycosylation3011N-linked (GlcNAc...) Potential
Glycosylation3741N-linked (GlcNAc...) Potential
Glycosylation4041N-linked (GlcNAc...) Potential
Glycosylation4091N-linked (GlcNAc...) Potential
Glycosylation4811N-linked (GlcNAc...) Potential
Glycosylation5161N-linked (GlcNAc...) Potential
Glycosylation5451N-linked (GlcNAc...) Potential
Glycosylation5741N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9P327 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: B39A773E76CD694B

FASTA67374,596
        10         20         30         40         50         60 
MYVNYIGLFA FVQISLTLAY PPGRVEISEI YDFEESSSYK GQDIDTSVLY TLSKRKPALV 

        70         80         90        100        110        120 
KRSTDASYAP FNVTCSNDNL LRPASEGLNE GEQSYINKRI SKVNSELRSF ISKTGLNVDL 

       130        140        150        160        170        180 
DKVVNSSDGP RLGIAFSGGG LRAMVNGGGA FNAFDSRFES DSPLSGLLQS AMYISGLSGG 

       190        200        210        220        230        240 
SWLVGSVAIN NFTNITYLRD NVWNLEHSVF APHGDNVIEN LNYYNDLRKE IDQKKHAGFD 

       250        260        270        280        290        300 
CSLTDLWGRA LSRKLVDAER GGPGITYSSM RNQSWFQNAD YPYPIIVADS RLEEETAIPA 

       310        320        330        340        350        360 
NTSIFEFTAY EFGTWDNGIK AFIPMEYVGT HLLDGVPPDK SCIHNYDNAG FVMGTSATLF 

       370        380        390        400        410        420 
NSFLLDWNEN VKKNDTYYDI LHAILEDLSK HQDDIAPYPN PYQNYTTSNT SVVNAFEPYD 

       430        440        450        460        470        480 
TIDLVDGGED RENIPLWPLL HPQRFVDVVF AIDSTYNDPY GWPLGSSIVA TYERVVTFNA 

       490        500        510        520        530        540 
NKSVDVRGFP YIPDENTIIS LGLNTRPTFF GCDGKNTTAG NHDVDNNTPP LLVYFPNYPW 

       550        560        570        580        590        600 
TYYSNISTFT MSMDDKMANG ILENAFMSTT QNNNESFAVC LACAIIQRSL ERKKLSTPTQ 

       610        620        630        640        650        660 
CSSCFQEYCW DGTLATSTAS VYDPTVMSAA TTSRAPSGTT SGTASSTTSS SVASATPTHK 

       670 
HWWDSIFEAK ENP 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[2]"Identification of open reading frames in Schizosaccharomyces pombe cDNAs."
Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.
DNA Res. 4:363-369(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 427-673.
Strain: PR745.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329671 Genomic DNA. Translation: CAB94277.1.
CU329670 Genomic DNA. Translation: CAB69631.1.
D89183 mRNA. Translation: BAA13845.1.
PIRT50281.
RefSeqNP_592772.1. NM_001020935.2.
NP_592781.1. NM_001018181.2.

3D structure databases

ProteinModelPortalQ9P327.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid857870. 42 interactions.
MINTMINT-4703485.
STRING4896.SPBC1348.10c-1.

Proteomic databases

PaxDbQ9P327.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPAC977.09c.1; SPAC977.09c.1:pep; SPAC977.09c.
SPBC1348.10c.1; SPBC1348.10c.1:pep; SPBC1348.10c.
GeneID2541836.
5802732.
KEGGspo:SPAC977.09c.
spo:SPBC1348.10c.

Organism-specific databases

PomBaseSPAC977.09c.
SPBC1348.10c.

Phylogenomic databases

eggNOGNOG271081.
HOGENOMHOG000189547.
KOK13333.
OMALQSATYM.
OrthoDBEOG7N37NC.
PhylomeDBQ9P327.

Family and domain databases

InterProIPR016035. Acyl_Trfase/lysoPLipase.
IPR002642. LysoPLipase_cat_dom.
[Graphical view]
PfamPF01735. PLA2_B. 1 hit.
[Graphical view]
SMARTSM00022. PLAc. 1 hit.
[Graphical view]
SUPFAMSSF52151. SSF52151. 1 hit.
PROSITEPS51210. PLA2C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20802924.

Entry information

Entry namePLB4_SCHPO
AccessionPrimary (citable) accession number: Q9P327
Secondary accession number(s): P78834
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names