Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9P2Z0

- THA10_HUMAN

UniProt

Q9P2Z0 - THA10_HUMAN

Protein

THAP domain-containing protein 10

Gene

THAP10

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri1 – 9090THAP-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    THAP domain-containing protein 10
    Gene namesi
    Name:THAP10
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 15

    Organism-specific databases

    HGNCiHGNC:23193. THAP10.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134988462.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 257257THAP domain-containing protein 10PRO_0000068651Add
    BLAST

    Proteomic databases

    PaxDbiQ9P2Z0.
    PRIDEiQ9P2Z0.

    PTM databases

    PhosphoSiteiQ9P2Z0.

    Expressioni

    Gene expression databases

    BgeeiQ9P2Z0.
    CleanExiHS_THAP10.
    GenevestigatoriQ9P2Z0.

    Organism-specific databases

    HPAiHPA041416.

    Interactioni

    Protein-protein interaction databases

    BioGridi121236. 3 interactions.
    IntActiQ9P2Z0. 3 interactions.
    MINTiMINT-1473877.
    STRINGi9606.ENSP00000249861.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9P2Z0.
    SMRiQ9P2Z0. Positions 1-92.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 THAP-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri1 – 9090THAP-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG67707.
    HOGENOMiHOG000059577.
    HOVERGENiHBG079250.
    InParanoidiQ9P2Z0.
    OMAiHRSVGIQ.
    OrthoDBiEOG7TF79Z.
    PhylomeDBiQ9P2Z0.
    TreeFamiTF330127.

    Family and domain databases

    InterProiIPR006612. Znf_C2CH.
    [Graphical view]
    PfamiPF05485. THAP. 1 hit.
    [Graphical view]
    SMARTiSM00692. DM3. 1 hit.
    SM00980. THAP. 1 hit.
    [Graphical view]
    PROSITEiPS50950. ZF_THAP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9P2Z0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPARCVAAHC GNTTKSGKSL FRFPKDRAVR LLWDRFVRGC RADWYGGNDR    50
    SVICSDHFAP ACFDVSSVIQ KNLRFSQRLR LVAGAVPTLH RVPAPAPKRG 100
    EEGDQAGRLD TRGELQAARH SEAAPGPVSC TRPRAGKQAA ASQITCENEL 150
    VQTQPHADNP SNTVTSVPTH CEEGPVHKST QISLKRPRHR SVGIQAKVKA 200
    FGKRLCNATT QTEELWSRTS SLFDIYSSDS ETDTDWDIKS EQSDLSYMAV 250
    QVKEETC 257
    Length:257
    Mass (Da):28,351
    Last modified:October 1, 2000 - v1
    Checksum:i912602126537AD41
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL360202 mRNA. Translation: CAB96109.1.
    AK313472 mRNA. Translation: BAG36257.1.
    CH471082 Genomic DNA. Translation: EAW77863.1.
    BC027857 mRNA. Translation: AAH27857.1.
    BC072414 mRNA. Translation: AAH72414.1.
    CCDSiCCDS10237.1.
    RefSeqiNP_064532.1. NM_020147.3.
    UniGeneiHs.591123.

    Genome annotation databases

    EnsembliENST00000249861; ENSP00000249861; ENSG00000129028.
    GeneIDi56906.
    KEGGihsa:56906.
    UCSCiuc002asv.3. human.

    Polymorphism databases

    DMDMi41018369.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL360202 mRNA. Translation: CAB96109.1 .
    AK313472 mRNA. Translation: BAG36257.1 .
    CH471082 Genomic DNA. Translation: EAW77863.1 .
    BC027857 mRNA. Translation: AAH27857.1 .
    BC072414 mRNA. Translation: AAH72414.1 .
    CCDSi CCDS10237.1.
    RefSeqi NP_064532.1. NM_020147.3.
    UniGenei Hs.591123.

    3D structure databases

    ProteinModelPortali Q9P2Z0.
    SMRi Q9P2Z0. Positions 1-92.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 121236. 3 interactions.
    IntActi Q9P2Z0. 3 interactions.
    MINTi MINT-1473877.
    STRINGi 9606.ENSP00000249861.

    PTM databases

    PhosphoSitei Q9P2Z0.

    Polymorphism databases

    DMDMi 41018369.

    Proteomic databases

    PaxDbi Q9P2Z0.
    PRIDEi Q9P2Z0.

    Protocols and materials databases

    DNASUi 56906.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000249861 ; ENSP00000249861 ; ENSG00000129028 .
    GeneIDi 56906.
    KEGGi hsa:56906.
    UCSCi uc002asv.3. human.

    Organism-specific databases

    CTDi 56906.
    GeneCardsi GC15M071173.
    HGNCi HGNC:23193. THAP10.
    HPAi HPA041416.
    MIMi 612538. gene.
    neXtProti NX_Q9P2Z0.
    PharmGKBi PA134988462.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG67707.
    HOGENOMi HOG000059577.
    HOVERGENi HBG079250.
    InParanoidi Q9P2Z0.
    OMAi HRSVGIQ.
    OrthoDBi EOG7TF79Z.
    PhylomeDBi Q9P2Z0.
    TreeFami TF330127.

    Miscellaneous databases

    GenomeRNAii 56906.
    NextBioi 62375.
    PROi Q9P2Z0.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9P2Z0.
    CleanExi HS_THAP10.
    Genevestigatori Q9P2Z0.

    Family and domain databases

    InterProi IPR006612. Znf_C2CH.
    [Graphical view ]
    Pfami PF05485. THAP. 1 hit.
    [Graphical view ]
    SMARTi SM00692. DM3. 1 hit.
    SM00980. THAP. 1 hit.
    [Graphical view ]
    PROSITEi PS50950. ZF_THAP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. The European IMAGE consortium
      Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Substantia nigra.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Pancreas and Skin.

    Entry informationi

    Entry nameiTHA10_HUMAN
    AccessioniPrimary (citable) accession number: Q9P2Z0
    Secondary accession number(s): B2R8R0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 16, 2004
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 15
      Human chromosome 15: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3