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Q9P2Z0

- THA10_HUMAN

UniProt

Q9P2Z0 - THA10_HUMAN

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Protein

THAP domain-containing protein 10

Gene
THAP10
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri1 – 9090THAP-typeAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
THAP domain-containing protein 10
Gene namesi
Name:THAP10
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 15

Organism-specific databases

HGNCiHGNC:23193. THAP10.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134988462.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 257257THAP domain-containing protein 10PRO_0000068651Add
BLAST

Proteomic databases

PaxDbiQ9P2Z0.
PRIDEiQ9P2Z0.

PTM databases

PhosphoSiteiQ9P2Z0.

Expressioni

Gene expression databases

BgeeiQ9P2Z0.
CleanExiHS_THAP10.
GenevestigatoriQ9P2Z0.

Organism-specific databases

HPAiHPA041416.

Interactioni

Protein-protein interaction databases

BioGridi121236. 3 interactions.
IntActiQ9P2Z0. 3 interactions.
MINTiMINT-1473877.
STRINGi9606.ENSP00000249861.

Structurei

3D structure databases

ProteinModelPortaliQ9P2Z0.
SMRiQ9P2Z0. Positions 1-92.

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri1 – 9090THAP-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG67707.
HOGENOMiHOG000059577.
HOVERGENiHBG079250.
InParanoidiQ9P2Z0.
OMAiHRSVGIQ.
OrthoDBiEOG7TF79Z.
PhylomeDBiQ9P2Z0.
TreeFamiTF330127.

Family and domain databases

InterProiIPR006612. Znf_C2CH.
[Graphical view]
PfamiPF05485. THAP. 1 hit.
[Graphical view]
SMARTiSM00692. DM3. 1 hit.
SM00980. THAP. 1 hit.
[Graphical view]
PROSITEiPS50950. ZF_THAP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P2Z0-1 [UniParc]FASTAAdd to Basket

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MPARCVAAHC GNTTKSGKSL FRFPKDRAVR LLWDRFVRGC RADWYGGNDR    50
SVICSDHFAP ACFDVSSVIQ KNLRFSQRLR LVAGAVPTLH RVPAPAPKRG 100
EEGDQAGRLD TRGELQAARH SEAAPGPVSC TRPRAGKQAA ASQITCENEL 150
VQTQPHADNP SNTVTSVPTH CEEGPVHKST QISLKRPRHR SVGIQAKVKA 200
FGKRLCNATT QTEELWSRTS SLFDIYSSDS ETDTDWDIKS EQSDLSYMAV 250
QVKEETC 257
Length:257
Mass (Da):28,351
Last modified:October 1, 2000 - v1
Checksum:i912602126537AD41
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL360202 mRNA. Translation: CAB96109.1.
AK313472 mRNA. Translation: BAG36257.1.
CH471082 Genomic DNA. Translation: EAW77863.1.
BC027857 mRNA. Translation: AAH27857.1.
BC072414 mRNA. Translation: AAH72414.1.
CCDSiCCDS10237.1.
RefSeqiNP_064532.1. NM_020147.3.
UniGeneiHs.591123.

Genome annotation databases

EnsembliENST00000249861; ENSP00000249861; ENSG00000129028.
GeneIDi56906.
KEGGihsa:56906.
UCSCiuc002asv.3. human.

Polymorphism databases

DMDMi41018369.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL360202 mRNA. Translation: CAB96109.1 .
AK313472 mRNA. Translation: BAG36257.1 .
CH471082 Genomic DNA. Translation: EAW77863.1 .
BC027857 mRNA. Translation: AAH27857.1 .
BC072414 mRNA. Translation: AAH72414.1 .
CCDSi CCDS10237.1.
RefSeqi NP_064532.1. NM_020147.3.
UniGenei Hs.591123.

3D structure databases

ProteinModelPortali Q9P2Z0.
SMRi Q9P2Z0. Positions 1-92.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121236. 3 interactions.
IntActi Q9P2Z0. 3 interactions.
MINTi MINT-1473877.
STRINGi 9606.ENSP00000249861.

PTM databases

PhosphoSitei Q9P2Z0.

Polymorphism databases

DMDMi 41018369.

Proteomic databases

PaxDbi Q9P2Z0.
PRIDEi Q9P2Z0.

Protocols and materials databases

DNASUi 56906.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000249861 ; ENSP00000249861 ; ENSG00000129028 .
GeneIDi 56906.
KEGGi hsa:56906.
UCSCi uc002asv.3. human.

Organism-specific databases

CTDi 56906.
GeneCardsi GC15M071173.
HGNCi HGNC:23193. THAP10.
HPAi HPA041416.
MIMi 612538. gene.
neXtProti NX_Q9P2Z0.
PharmGKBi PA134988462.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG67707.
HOGENOMi HOG000059577.
HOVERGENi HBG079250.
InParanoidi Q9P2Z0.
OMAi HRSVGIQ.
OrthoDBi EOG7TF79Z.
PhylomeDBi Q9P2Z0.
TreeFami TF330127.

Miscellaneous databases

GenomeRNAii 56906.
NextBioi 62375.
PROi Q9P2Z0.
SOURCEi Search...

Gene expression databases

Bgeei Q9P2Z0.
CleanExi HS_THAP10.
Genevestigatori Q9P2Z0.

Family and domain databases

InterProi IPR006612. Znf_C2CH.
[Graphical view ]
Pfami PF05485. THAP. 1 hit.
[Graphical view ]
SMARTi SM00692. DM3. 1 hit.
SM00980. THAP. 1 hit.
[Graphical view ]
PROSITEi PS50950. ZF_THAP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. The European IMAGE consortium
    Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Substantia nigra.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Pancreas and Skin.

Entry informationi

Entry nameiTHA10_HUMAN
AccessioniPrimary (citable) accession number: Q9P2Z0
Secondary accession number(s): B2R8R0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: October 1, 2000
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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