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Q9P2Z0 (THA10_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
THAP domain-containing protein 10
Gene names
Name:THAP10
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length257 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 THAP-type zinc finger.

Ontologies

Keywords
   DomainZinc-finger
   LigandDNA-binding
Metal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 257257THAP domain-containing protein 10
PRO_0000068651

Regions

Zinc finger1 – 9090THAP-type

Sequences

Sequence LengthMass (Da)Tools
Q9P2Z0 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 912602126537AD41

FASTA25728,351
        10         20         30         40         50         60 
MPARCVAAHC GNTTKSGKSL FRFPKDRAVR LLWDRFVRGC RADWYGGNDR SVICSDHFAP 

        70         80         90        100        110        120 
ACFDVSSVIQ KNLRFSQRLR LVAGAVPTLH RVPAPAPKRG EEGDQAGRLD TRGELQAARH 

       130        140        150        160        170        180 
SEAAPGPVSC TRPRAGKQAA ASQITCENEL VQTQPHADNP SNTVTSVPTH CEEGPVHKST 

       190        200        210        220        230        240 
QISLKRPRHR SVGIQAKVKA FGKRLCNATT QTEELWSRTS SLFDIYSSDS ETDTDWDIKS 

       250 
EQSDLSYMAV QVKEETC 

« Hide

References

[1]The European IMAGE consortium
Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Substantia nigra.
[3]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Pancreas and Skin.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL360202 mRNA. Translation: CAB96109.1.
AK313472 mRNA. Translation: BAG36257.1.
CH471082 Genomic DNA. Translation: EAW77863.1.
BC027857 mRNA. Translation: AAH27857.1.
BC072414 mRNA. Translation: AAH72414.1.
RefSeqNP_064532.1. NM_020147.3.
UniGeneHs.591123.

3D structure databases

ProteinModelPortalQ9P2Z0.
SMRQ9P2Z0. Positions 1-93.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid121236. 3 interactions.
IntActQ9P2Z0. 3 interactions.
MINTMINT-1473877.
STRING9606.ENSP00000249861.

PTM databases

PhosphoSiteQ9P2Z0.

Polymorphism databases

DMDM41018369.

Proteomic databases

PaxDbQ9P2Z0.
PRIDEQ9P2Z0.

Protocols and materials databases

DNASU56906.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000249861; ENSP00000249861; ENSG00000129028.
GeneID56906.
KEGGhsa:56906.
UCSCuc002asv.3. human.

Organism-specific databases

CTD56906.
GeneCardsGC15M071173.
HGNCHGNC:23193. THAP10.
HPAHPA041416.
MIM612538. gene.
neXtProtNX_Q9P2Z0.
PharmGKBPA134988462.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG67707.
HOGENOMHOG000059577.
HOVERGENHBG079250.
InParanoidQ9P2Z0.
OMAHRSVGIQ.
OrthoDBEOG7TF79Z.
PhylomeDBQ9P2Z0.
TreeFamTF330127.

Gene expression databases

BgeeQ9P2Z0.
CleanExHS_THAP10.
GenevestigatorQ9P2Z0.

Family and domain databases

InterProIPR006612. Znf_C2CH.
[Graphical view]
PfamPF05485. THAP. 1 hit.
[Graphical view]
SMARTSM00692. DM3. 1 hit.
SM00980. THAP. 1 hit.
[Graphical view]
PROSITEPS50950. ZF_THAP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi56906.
NextBio62375.
PROQ9P2Z0.
SOURCESearch...

Entry information

Entry nameTHA10_HUMAN
AccessionPrimary (citable) accession number: Q9P2Z0
Secondary accession number(s): B2R8R0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: October 1, 2000
Last modified: March 19, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 15

Human chromosome 15: entries, gene names and cross-references to MIM