Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

THAP domain-containing protein 10

Gene

THAP10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1 – 90THAP-typePROSITE-ProRule annotationAdd BLAST90

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
THAP domain-containing protein 10
Gene namesi
Name:THAP10
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

EuPathDBiHostDB:ENSG00000129028.8
HGNCiHGNC:23193 THAP10
MIMi612538 gene
neXtProtiNX_Q9P2Z0

Pathology & Biotechi

Organism-specific databases

DisGeNETi56906
OpenTargetsiENSG00000129028
PharmGKBiPA134988462

Polymorphism and mutation databases

BioMutaiTHAP10
DMDMi41018369

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000686511 – 257THAP domain-containing protein 10Add BLAST257

Proteomic databases

MaxQBiQ9P2Z0
PaxDbiQ9P2Z0
PeptideAtlasiQ9P2Z0
PRIDEiQ9P2Z0

PTM databases

iPTMnetiQ9P2Z0
PhosphoSitePlusiQ9P2Z0

Expressioni

Gene expression databases

BgeeiENSG00000129028
CleanExiHS_THAP10
ExpressionAtlasiQ9P2Z0 baseline and differential
GenevisibleiQ9P2Z0 HS

Organism-specific databases

HPAiHPA041416

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi121236, 11 interactors
IntActiQ9P2Z0, 10 interactors
MINTiQ9P2Z0
STRINGi9606.ENSP00000249861

Structurei

3D structure databases

ProteinModelPortaliQ9P2Z0
SMRiQ9P2Z0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri1 – 90THAP-typePROSITE-ProRule annotationAdd BLAST90

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IX5Q Eukaryota
ENOG410Z0YS LUCA
GeneTreeiENSGT00510000050001
HOGENOMiHOG000059577
HOVERGENiHBG079250
InParanoidiQ9P2Z0
OMAiTRPRAGK
OrthoDBiEOG091G0MV4
PhylomeDBiQ9P2Z0
TreeFamiTF330127

Family and domain databases

Gene3Di3.30.40.180, 1 hit
InterProiView protein in InterPro
IPR006612 THAP_Znf
IPR038441 THAP_Znf_sf
PfamiView protein in Pfam
PF05485 THAP, 1 hit
SMARTiView protein in SMART
SM00692 DM3, 1 hit
SM00980 THAP, 1 hit
PROSITEiView protein in PROSITE
PS50950 ZF_THAP, 1 hit

Sequencei

Sequence statusi: Complete.

Q9P2Z0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPARCVAAHC GNTTKSGKSL FRFPKDRAVR LLWDRFVRGC RADWYGGNDR
60 70 80 90 100
SVICSDHFAP ACFDVSSVIQ KNLRFSQRLR LVAGAVPTLH RVPAPAPKRG
110 120 130 140 150
EEGDQAGRLD TRGELQAARH SEAAPGPVSC TRPRAGKQAA ASQITCENEL
160 170 180 190 200
VQTQPHADNP SNTVTSVPTH CEEGPVHKST QISLKRPRHR SVGIQAKVKA
210 220 230 240 250
FGKRLCNATT QTEELWSRTS SLFDIYSSDS ETDTDWDIKS EQSDLSYMAV

QVKEETC
Length:257
Mass (Da):28,351
Last modified:October 1, 2000 - v1
Checksum:i912602126537AD41
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL360202 mRNA Translation: CAB96109.1
AK313472 mRNA Translation: BAG36257.1
CH471082 Genomic DNA Translation: EAW77863.1
BC027857 mRNA Translation: AAH27857.1
BC072414 mRNA Translation: AAH72414.1
CCDSiCCDS10237.1
RefSeqiNP_064532.1, NM_020147.3
UniGeneiHs.591123

Genome annotation databases

EnsembliENST00000249861; ENSP00000249861; ENSG00000129028
GeneIDi56906
KEGGihsa:56906
UCSCiuc002asv.4 human

Similar proteinsi

Entry informationi

Entry nameiTHA10_HUMAN
AccessioniPrimary (citable) accession number: Q9P2Z0
Secondary accession number(s): B2R8R0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: October 1, 2000
Last modified: March 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health