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Q9P2P6 (STAR9_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
StAR-related lipid transfer protein 9
Alternative name(s):
START domain-containing protein 9
Short name=StARD9
Gene names
Name:STARD9
Synonyms:KIAA1300
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length4700 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM). Ref.6

Subunit structure

Interacts with ATAD3A. Ref.7

Subcellular location

Cytoplasmcytoskeletonmicrotubule organizing centercentrosomecentriole. Nucleus. Note: Localizes throughout the cytoplasm and nucleus during interphase. Localizes to the daughter centriole during mitosis. Disappears in cytokinesis. Ref.6

Tissue specificity

Expressed in the central nervous system, muscle cells (heart and skeletal muscle), pancreas, prostate and lung. Ref.5

Sequence similarities

Belongs to the kinesin-like protein family.

Contains 1 FHA domain.

Contains 1 kinesin-motor domain.

Contains 1 START domain.

Sequence caution

The sequence CAH18258.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

The sequence CAH18258.1 differs from that shown. Reason: Erroneous termination at position 2903. Translated as Gln.

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9P2P6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9P2P6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     290-292: AQN → GIF
     293-4700: Missing.
Note: No experimental confirmation available.
Isoform 3 (identifier: Q9P2P6-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-84: Missing.
     360-435: TVSPAHTSYS...DENLKELVLQ → SEWDARAGPV...SISEKGPWPQ
     436-4700: Missing.
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 47004700StAR-related lipid transfer protein 9
PRO_0000220678

Regions

Domain1 – 277277Kinesin-motor
Domain498 – 56972FHA
Domain4483 – 4700218START
Nucleotide binding103 – 1108ATP Potential
Coiled coil4334 – 438754 Potential
Compositional bias649 – 71163Gln-rich
Compositional bias1917 – 19204Poly-Glu
Compositional bias2696 – 26994Poly-Ser

Natural variations

Alternative sequence1 – 8484Missing in isoform 3.
VSP_029573
Alternative sequence290 – 2923AQN → GIF in isoform 2.
VSP_029574
Alternative sequence293 – 47004408Missing in isoform 2.
VSP_029575
Alternative sequence360 – 43576TVSPA…ELVLQ → SEWDARAGPVLGLVLYLRER AMAPVSGMPELDLCWDWYSI SEKGPWPQ in isoform 3.
VSP_029576
Alternative sequence436 – 47004265Missing in isoform 3.
VSP_029577
Natural variant8351R → C.
Corresponds to variant rs12594837 [ dbSNP | Ensembl ].
VAR_059811
Natural variant11721R → C.
Corresponds to variant rs12594837 [ dbSNP | Ensembl ].
VAR_037257
Natural variant17201P → L.
Corresponds to variant rs7161810 [ dbSNP | Ensembl ].
VAR_037258
Natural variant22051A → V.
Corresponds to variant rs16957055 [ dbSNP | Ensembl ].
VAR_037259
Natural variant26771R → H.
Corresponds to variant rs8030587 [ dbSNP | Ensembl ].
VAR_037260
Natural variant28551T → I.
Corresponds to variant rs8031218 [ dbSNP | Ensembl ].
VAR_037261
Natural variant28691P → S.
Corresponds to variant rs11857283 [ dbSNP | Ensembl ].
VAR_037262
Natural variant30151R → G.
Corresponds to variant rs3742995 [ dbSNP | Ensembl ].
VAR_037263
Natural variant33831N → D. Ref.4
Corresponds to variant rs3742993 [ dbSNP | Ensembl ].
VAR_037264
Natural variant34691Y → C.
Corresponds to variant rs16957061 [ dbSNP | Ensembl ].
VAR_037266

Experimental info

Mutagenesis1101T → N: Reduced ATPase activity. Ref.6
Mutagenesis2231R → A: Reduced ability to bind microtubules. Ref.6
Sequence conflict26021S → L in CAH18258. Ref.2
Sequence conflict28181T → I in CAH18258. Ref.2
Sequence conflict36331T → A in CAH18258. Ref.2
Sequence conflict4433 – 44386LPDSRD → IPGIRQ in CAB63725. Ref.2
Sequence conflict46391R → H in BAA92538. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified February 22, 2012. Version 3.
Checksum: D422BEE9E5612036

FASTA4,700516,343
        10         20         30         40         50         60 
MANVQVAVRV RPLSKRETKE GGRIIVEVDG KVAKIRNLKV DNRPDGFGDS REKVMAFGFD 

        70         80         90        100        110        120 
YCYWSVNPED PQYASQDVVF QDLGMEVLSG VAKGYNICLF AYGQTGSGKT YTMLGTPASV 

       130        140        150        160        170        180 
GLTPRICEGL FVREKDCASL PSSCRIKVSF LEIYNERVRD LLKQSGQKKS YTLRVREHPE 

       190        200        210        220        230        240 
MGPYVQGLSQ HVVTNYKQVI QLLEEGIANR ITAATHVHEA SSRSHAIFTI HYTQAILENN 

       250        260        270        280        290        300 
LPSEMASKIN LVDLAGSERA DPSYCKDRIA EGANINKSLV TLGIVISTLA QNSQVFSSCQ 

       310        320        330        340        350        360 
SLNSSVSNGG DSGILSSPSG TSSGGAPSRR QSYIPYRDSV LTWLLKDSLG GNSKTIMVAT 

       370        380        390        400        410        420 
VSPAHTSYSE TMSTLRYASS AKNIINKPRV NEDANLKLIR ELREEIERLK ALLLSFELRN 

       430        440        450        460        470        480 
FSSLSDENLK ELVLQNELKI DQLTKDWTQK WNDWQALMEH YSVDINRRRA GVVIDSSLPH 

       490        500        510        520        530        540 
LMALEDDVLS TGVVLYHLKE GTTKIGRIDS DQEQDIVLQG QWIERDHCTI TSACGVVVLR 

       550        560        570        580        590        600 
PARGARCTVN GREVTASCRL TQGAVITLGK AQKFRFNHPA EAAVLRQRRQ VGEAAAGRGS 

       610        620        630        640        650        660 
LEWLDLDGDL AASRLGLSPL LWKERRALEE QCDEDHQTPR DGETSHRAQI QQQQSYVEDL 

       670        680        690        700        710        720 
RHQILAEEIR AAKELEFDQA WISQQIKENQ QCLLREETWL ASLQQQQQED QVAEKELEAS 

       730        740        750        760        770        780 
VALDAWLQTD PEIQPSPFVQ SQKRVVHLQL LRRHTLRAAE RNVRRKKVSF QLERIIKKQR 

       790        800        810        820        830        840 
LLEAQKRLEK LTTLCWLQDD STQEPPYQVL SPDATVPRPP CRSKLTSCSS LSPQRLCSKH 

       850        860        870        880        890        900 
MPQLHSIFLS WDPSTTLPPR PDPTHQTSEK TSSEEHLPQA ASYPARTGCL RKNGLHSSGH 

       910        920        930        940        950        960 
GQPCTARAAL ARKGASAPDA CLTMSPNSVG IQEMEMGVKQ PHQMVSQGLA SLRKSANKLK 

       970        980        990       1000       1010       1020 
PRHEPKIFTS TTQTRGAKGL ADPSHTQAGW RKEGNLGTHK AAKGASCNSL YPHGPRQTAG 

      1030       1040       1050       1060       1070       1080 
HGKAVKTFWT EYKPPSPSRA SKRHQRVLAT RVRNITKKSS HLPLGSPLKR QQNTRDPDTM 

      1090       1100       1110       1120       1130       1140 
VPLTDFSPVM DHSREKDNDL SDTDSNYSLD SLSCVYAKAL IEPLKPEERK WDFPEPENSE 

      1150       1160       1170       1180       1190       1200 
SDDSQLSEDS LAEKRYQSPK NRLGGNRPTN NRGQPRTRTR ASVRGFTAAS DSDLLAQTHR 

      1210       1220       1230       1240       1250       1260 
SFSLDSLIDA EEELGEDQQE EPFPGSADEI PTETFWHLED SSLPVMDQEA ICRLGPINYR 

      1270       1280       1290       1300       1310       1320 
TAARLDAVLP MSSSFYLDPQ FQPHCELQPH CELQPHCELQ PHCEQAESQV EPSYSEQADS 

      1330       1340       1350       1360       1370       1380 
LQGMQLSRES PLMSMDSWFS CDSKINPSSP PGIVGSLCPS PDMQEFHSCK GERPGYWPNT 

      1390       1400       1410       1420       1430       1440 
EELKPSDAET VLPYSSKLHQ GSTELLCSAR DEHTASAADT SRLSLWGIQR LIQPGADGTF 

      1450       1460       1470       1480       1490       1500 
QGRCIPDMTQ QGSSEASHNS SVSNVLAASA TTLTHVGSTH ERDWSALQQK YLLELSCPVL 

      1510       1520       1530       1540       1550       1560 
EAIGAPKPAY PYLEEDSGSL AQASSKGGDT LLPVGPRVSS NLNLNNFPVH LSRIRRLRAE 

      1570       1580       1590       1600       1610       1620 
KEQDSLNAKL EGVSDFFSTS EKEASYDETY SADLESLSAS RSTNAQVFAT ENAIPDSMTE 

      1630       1640       1650       1660       1670       1680 
ACEVKQNNLE ECLQSCRKPG LMTSSDEDFF QKNACHSNVT TATKADHWSQ GWAPLRKNSA 

      1690       1700       1710       1720       1730       1740 
VQPGQLSPDS HYPLEEEKTD CQESSKEAVR RHINVSFALP SGPELYLHSA PWNPLSSSLQ 

      1750       1760       1770       1780       1790       1800 
PPLLETFYVT KSRDALTETA LEIPACREVR VPSPPPREAW GFGHNHQALQ GAYLKNNLPV 

      1810       1820       1830       1840       1850       1860 
LLQNQNSKIA SSQQVTAEIP VDLNTREVIR ESGKCPGNIT EESHDSVYSS VTQNRHFLPS 

      1870       1880       1890       1900       1910       1920 
TSTKVCEFEN QVVILNKKHS FPALEGGEVT AQSCCGASSD STESGKSLLF RESEAREEEE 

      1930       1940       1950       1960       1970       1980 
LDQNTVLRQT INVSLEKDMP GESAVSLKSR SVDRRVSSPV MVAQGGGPTP KWEGKNETGL 

      1990       2000       2010       2020       2030       2040 
LEKGLRPKDS SEEFKLPGTK PAYERFQLVA CPQERNPSEC KSQEMLNPNR EPSGKKQNKR 

      2050       2060       2070       2080       2090       2100 
VNNTDEMARL IRSVMQLENG ILEIESKQNK QVHASHTPGT DKELVFQDQK EQEKTDHAFR 

      2110       2120       2130       2140       2150       2160 
PDSSGNPLPS KDQPSSPRQT DDTVFRDSEA GAMEVNSIGN HPQVQKITPN PFRSREGVRE 

      2170       2180       2190       2200       2210       2220 
SEPVREHTHP AGSDRPARDI CDSLGKHTTC REFTNTSLHP QRMKALARAL PLQPRLERSS 

      2230       2240       2250       2260       2270       2280 
KNNGQFVKAS ASLKGQPWGL GSLEELETVK GFQESQVAEH VSSSNQEEPK AQGKVEEMPM 

      2290       2300       2310       2320       2330       2340 
QRGGSLQEEN KVTQKFPSLS QLCRDTFFRQ ETVSPLLSRT EFCTAPLHQD LSNTLPLNSP 

      2350       2360       2370       2380       2390       2400 
RWPRRCLHVP VALGISSLDC VLDLTMLKIH NSPLVTGVEH QDQSTETRSH SPEGNVRGRS 

      2410       2420       2430       2440       2450       2460 
SEAHTAWCGS VRSMAMGSHS QSGVPESIPL GTEDRISAST SPQDHGKDLR ITLLGFSTSE 

      2470       2480       2490       2500       2510       2520 
DFASEAEVAV QKEIRVSSLN KVSSQPEKRV SFSLEEDSDQ ASKPRQKAEK ETEDVGLTSG 

      2530       2540       2550       2560       2570       2580 
VSLAPVSLPR VPSPEPRLLE PSDHASMCLA ILEEIRQAKA QRKQLHDFVA RGTVLSYCET 

      2590       2600       2610       2620       2630       2640 
LLEPECSSRV AGRPQCKQID QSSSDQTRNE GEAPGFHVAS LSAEAGQIDL LPDERKVQAT 

      2650       2660       2670       2680       2690       2700 
SLSADSFESL PNTETDREPW DPVQAFSHAA PAQDRKRRTG ELRQFAGASE PFICHSSSSE 

      2710       2720       2730       2740       2750       2760 
IIEKKKDATR TPSSADPLAP DSPRSSAPVE EVRRVVSKKV VAALPSQAPY DDPRVTLHEL 

      2770       2780       2790       2800       2810       2820 
SQSVPQETAE GIPPGSQDSS PEHQEPRTLD TTYGEVSDNL LVTAQGEKTA HFESQSVTCD 

      2830       2840       2850       2860       2870       2880 
VQNSTSASGP KQDHVQCPEA STGFEEGRAS PKQDTILPGA LTRVALEAPT QQCVQCKESV 

      2890       2900       2910       2920       2930       2940 
GSGLTEVCRA GSKHSRPIPL PDQRPSANPG GIGEEAPCRH PREALDGPVF SRNPEGSRTL 

      2950       2960       2970       2980       2990       3000 
SPSRGKESRT LPCRQPCSSQ PVATHAYSSH SSTLLCFRDG DLGKEPFKAA PHTIHPPCVV 

      3010       3020       3030       3040       3050       3060 
PSRAYEMDET GEISRGPDVH LTHGLEPKDV NREFRLTESS TCEPSTVAAV LSRAQGCRSP 

      3070       3080       3090       3100       3110       3120 
SAPDVRTGSF SHSATDGSVG LIGVPEKKVA EKQASTELEA ASFPAGMYSE PLRQFRDSSV 

      3130       3140       3150       3160       3170       3180 
GDQNAQVCQT NPEPPATTQG PHTLDLSEGS AESKLVVEPQ HECLENTTRC FLEKPQFSTE 

      3190       3200       3210       3220       3230       3240 
LRDHNRLDSQ AKFVARLKHT CSPQEDSPWQ EEEQHRDQAS GGGEGFAQGV NPLPDEDGLD 

      3250       3260       3270       3280       3290       3300 
GCQILDAGRE EVAVAKPPVS KILSQGFKDP ATVSLRQNET PQPAAQRSGH LYTGREQPAP 

      3310       3320       3330       3340       3350       3360 
NHRGSLPVTT IFSGPKHSRS SPTPQFSVVG SSRSLQELNL SVEPPSPTDE DTQGPNRLWN 

      3370       3380       3390       3400       3410       3420 
PHLRGYSSGK SVARTSLQAE DSNQKASSRL DDGTTDHRHL KPATPPYPMP STLSHMPTPD 

      3430       3440       3450       3460       3470       3480 
FTTSWMSGTL EQAQQGKREK LGVQVRPENW CSQMDKGMLH FGSSDISPYA LPWRPEEPAR 

      3490       3500       3510       3520       3530       3540 
ISWKQYMSGS AVDVSCSQKP QGLTLSNVAR CSSMDNGLED QNSPFHSHLS TYANICDLST 

      3550       3560       3570       3580       3590       3600 
THSSTENAQG SNEAWEVFRG SSSIALGDPH IPTSPEGVAP TSGHDRRPQF RGPSGEADCL 

      3610       3620       3630       3640       3650       3660 
RSKPPLAKGS AAGPVDEIML LYPSEAGCPV GQTRTNTFEQ GTQTLGSRRH WSSTDISFAQ 

      3670       3680       3690       3700       3710       3720 
PEASAVSAFD LASWTSMHNL SLHLSQLLHS TSELLGSLSQ PDVARREQNT KRDIPDKAPQ 

      3730       3740       3750       3760       3770       3780 
ALMMDGSTQT TVDEGSQTDL TLPTLCLQTS EAEPQGANVI LEGLGSDTST VSQEEGDVPG 

      3790       3800       3810       3820       3830       3840 
VPQKREAEET AQKMAQLLYL QEESTPYKPQ SPSIPSSHLR FQKAPVGQHL PSVSPSVSDA 

      3850       3860       3870       3880       3890       3900 
FLPPSSQPEE SYCLVVSSPS PSSPHSPGLF PSTSEYPGDS RVQKKLGPTS ALFVDRASSP 

      3910       3920       3930       3940       3950       3960 
ILTLSASTQE PGLSPGSLTL SAPSTHPVEG HQKLDSSPDP VDAPRTPMDN YSQTTDELGG 

      3970       3980       3990       4000       4010       4020 
SQRGRSSLQR SNGRSFLELH SPHSPQQSPK LQFSFLGQHP QQLQPRTTIG VQSRLLPPPL 

      4030       4040       4050       4060       4070       4080 
RHRSQRLGNS FVPEKVASPE HCPLSGREPS QWQSRTENGG ESSASPGEPQ RTLDRPSSWG 

      4090       4100       4110       4120       4130       4140 
GLQHLSPCPV SELTDTAGLR GSALGLPQAC QPEELLCFSC QMCMAPEHQH HSLRDLPVHN 

      4150       4160       4170       4180       4190       4200 
KFSNWCGVQK GSPGGLDMTE EELGASGDLS SEKQEQSPPQ PPNDHSQDSE WSKREQIPLQ 

      4210       4220       4230       4240       4250       4260 
VGAQNLSLSV ELTEAKLHHG FGEADALLQV LQSGTGEALA ADEPVTSTWK ELYARQKKAI 

      4270       4280       4290       4300       4310       4320 
ETLRRERAER LGNFCRTRSL SPQKQLSLLP NKDLFIWDLD LPSRRREYLQ QLRKDVVETT 

      4330       4340       4350       4360       4370       4380 
RSPESVSRSA HTPSDIELML QDYQQAHEEA KVEIARARDQ LRERTEQEKL RIHQKIISQL 

      4390       4400       4410       4420       4430       4440 
LKEEDKLHTL ANSSSLCTSS NGSLSSGMTS GYNSSPALSG QLQFPENMGH TNLPDSRDVW 

      4450       4460       4470       4480       4490       4500 
IGDERGGHSA VRKNSAYSHR ASLGSCCCSP SSLSSLGTCF SSSYQDLAKH VVDTSMADVM 

      4510       4520       4530       4540       4550       4560 
AACSDNLHNL FSCQATAGWN YQGEEQAVQL YYKVFSPTRH GFLGAGVVSQ PLSRVWAAVS 

      4570       4580       4590       4600       4610       4620 
DPTVWPLYYK PIQTARLHQR VTNSISLVYL VCNTTLCALK QPRDFCCVCV EAKEGHLSVM 

      4630       4640       4650       4660       4670       4680 
AAQSVYDTSM PRPSRKMVRG EILPSAWILQ PITVEGKEVT RVIYLAQVEL GAPGFPPQLL 

      4690       4700 
SSFIKRQPLV IARLASFLGR 

« Hide

Isoform 2 [UniParc].

Checksum: 8BDCDCAEEF042674
Show »

FASTA29232,326
Isoform 3 [UniParc].

Checksum: 2981E165492842F6
Show »

FASTA32335,159

References

« Hide 'large scale' references
[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
Tissue: Thymus.
[2]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1975-4700 (ISOFORM 1).
Tissue: Cervix, Fetal kidney and Testis.
[3]"Analysis of the DNA sequence and duplication history of human chromosome 15."
Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N., Abouelleil A. expand/collapse author list , Arachchi H.M., Baradarani L., Birditt B., Bloom S., Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K., DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]"Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2881-4700 (ISOFORM 1), VARIANT ASP-3383.
Tissue: Brain.
[5]"Identification and characterization of the human StARD9 gene in the LGMD2A-region on chromosome 15q15 by in silico methods."
Halama N., Grauling-Halama S.A., Jager D.
Int. J. Mol. Med. 18:653-656(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION, TISSUE SPECIFICITY.
[6]"The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly."
Torres J.Z., Summers M.K., Peterson D., Brauer M.J., Lee J., Senese S., Gholkar A.A., Lo Y.C., Lei X., Jung K., Anderson D.C., Davis D.P., Belmont L., Jackson P.K.
Cell 147:1309-1323(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, MUTAGENESIS OF THR-110 AND ARG-223.
[7]"Mitochondrial nucleoid interacting proteins support mitochondrial protein synthesis."
He J., Cooper H.M., Reyes A., Di Re M., Sembongi H., Litwin T.R., Gao J., Neuman K.C., Fearnley I.M., Spinazzola A., Walker J.E., Holt I.J.
Nucleic Acids Res. 40:6109-6121(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH ATAD3A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK122666 mRNA. Translation: BAC85502.1.
AL133579 mRNA. Translation: CAB63725.1.
CR627426 mRNA. Translation: CAH10513.1.
CR749416 mRNA. Translation: CAH18258.1. Sequence problems.
AC018362 Genomic DNA. No translation available.
AC090510 Genomic DNA. No translation available.
AB037721 mRNA. Translation: BAA92538.1.
PIRT43486.
RefSeqNP_065810.2. NM_020759.2.
UniGeneHs.122061.

3D structure databases

ProteinModelPortalQ9P2P6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ9P2P6. 4 interactions.
MINTMINT-1432918.
STRING9606.ENSP00000290607.

PTM databases

PhosphoSiteQ9P2P6.

Polymorphism databases

DMDM378405232.

Proteomic databases

PaxDbQ9P2P6.
PRIDEQ9P2P6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000290607; ENSP00000290607; ENSG00000159433. [Q9P2P6-1]
GeneID57519.
KEGGhsa:57519.
UCSCuc010udj.2. human. [Q9P2P6-1]

Organism-specific databases

CTD57519.
GeneCardsGC15P042867.
HGNCHGNC:19162. STARD9.
HPAHPA014562.
MIM614642. gene.
neXtProtNX_Q9P2P6.
HUGESearch...
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG5059.
HOGENOMHOG000169805.
HOVERGENHBG108517.
InParanoidQ9P2P6.
KOK16491.
OMAELYARQK.
OrthoDBEOG7353VX.
TreeFamTF332626.

Gene expression databases

ArrayExpressQ9P2P6.
BgeeQ9P2P6.
CleanExHS_STARD9.
GenevestigatorQ9P2P6.

Family and domain databases

Gene3D2.60.200.20. 1 hit.
3.30.530.20. 1 hit.
3.40.850.10. 1 hit.
InterProIPR000253. FHA_dom.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
IPR008984. SMAD_FHA_domain.
IPR023393. START-like_dom.
IPR002913. START_lipid-bd_dom.
[Graphical view]
PfamPF00498. FHA. 1 hit.
PF00225. Kinesin. 1 hit.
PF01852. START. 1 hit.
[Graphical view]
PRINTSPR00380. KINESINHEAVY.
SMARTSM00240. FHA. 1 hit.
SM00129. KISc. 1 hit.
[Graphical view]
SUPFAMSSF49879. SSF49879. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEPS00411. KINESIN_MOTOR_DOMAIN1. 1 hit.
PS50067. KINESIN_MOTOR_DOMAIN2. 1 hit.
PS50848. START. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSSTARD9. human.
GenomeRNAi57519.
NextBio63889.
PROQ9P2P6.
SOURCESearch...

Entry information

Entry nameSTAR9_HUMAN
AccessionPrimary (citable) accession number: Q9P2P6
Secondary accession number(s): Q68DG2 expand/collapse secondary AC list , Q6AI01, Q6ZWK0, Q9UF70
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: February 22, 2012
Last modified: April 16, 2014
This is version 93 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 15

Human chromosome 15: entries, gene names and cross-references to MIM