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Protein

StAR-related lipid transfer protein 9

Gene

STARD9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM).1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi103 – 110ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity Source: GO_Central
  • ATP binding Source: UniProtKB-KW
  • lipid binding Source: InterPro
  • microtubule binding Source: UniProtKB
  • microtubule motor activity Source: UniProtKB

GO - Biological processi

  • cytoskeleton-dependent intracellular transport Source: GO_Central
  • metabolic process Source: UniProtKB
  • microtubule-based movement Source: GO_Central
  • spindle assembly Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Motor protein

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciZFISH:ENSG00000159433-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
StAR-related lipid transfer protein 9
Alternative name(s):
START domain-containing protein 9
Short name:
StARD9
Gene namesi
Name:STARD9
Synonyms:KIAA1300
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 15

Organism-specific databases

HGNCiHGNC:19162. STARD9.

Subcellular locationi

GO - Cellular componenti

  • centriole Source: UniProtKB
  • cytoplasm Source: UniProtKB
  • Golgi apparatus Source: HPA
  • kinesin complex Source: GO_Central
  • nucleoplasm Source: HPA
  • nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi110T → N: Reduced ATPase activity. 1 Publication1
Mutagenesisi223R → A: Reduced ability to bind microtubules. 1 Publication1

Organism-specific databases

OpenTargetsiENSG00000159433.

Polymorphism and mutation databases

BioMutaiSTARD9.
DMDMi378405232.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002206781 – 4700StAR-related lipid transfer protein 9Add BLAST4700

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1203PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9P2P6.
MaxQBiQ9P2P6.
PaxDbiQ9P2P6.
PeptideAtlasiQ9P2P6.
PRIDEiQ9P2P6.

PTM databases

iPTMnetiQ9P2P6.
PhosphoSitePlusiQ9P2P6.

Expressioni

Tissue specificityi

Expressed in the central nervous system, muscle cells (heart and skeletal muscle), pancreas, prostate and lung.1 Publication

Gene expression databases

BgeeiENSG00000159433.
CleanExiHS_STARD9.
ExpressionAtlasiQ9P2P6. baseline and differential.
GenevisibleiQ9P2P6. HS.

Organism-specific databases

HPAiHPA014562.

Interactioni

Subunit structurei

Interacts with ATAD3A.1 Publication

GO - Molecular functioni

  • microtubule binding Source: UniProtKB

Protein-protein interaction databases

BioGridi121580. 7 interactors.
IntActiQ9P2P6. 4 interactors.
MINTiMINT-1432918.
STRINGi9606.ENSP00000290607.

Structurei

3D structure databases

ProteinModelPortaliQ9P2P6.
SMRiQ9P2P6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 384Kinesin motorPROSITE-ProRule annotationAdd BLAST382
Domaini498 – 569FHAAdd BLAST72
Domaini4483 – 4700STARTPROSITE-ProRule annotationAdd BLAST218

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili4334 – 4387Sequence analysisAdd BLAST54

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi649 – 711Gln-richAdd BLAST63
Compositional biasi1917 – 1920Poly-Glu4
Compositional biasi2696 – 2699Poly-Ser4

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotation
Contains 1 FHA domain.Curated
Contains 1 kinesin motor domain.PROSITE-ProRule annotation
Contains 1 START domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0245. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00860000133823.
HOGENOMiHOG000169805.
HOVERGENiHBG108517.
InParanoidiQ9P2P6.
KOiK16491.
OMAiSDQEQDI.
OrthoDBiEOG091G00MR.
PhylomeDBiQ9P2P6.
TreeFamiTF332626.

Family and domain databases

Gene3Di2.60.200.20. 1 hit.
3.30.530.20. 1 hit.
3.40.850.10. 1 hit.
InterProiIPR000253. FHA_dom.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
IPR008984. SMAD_FHA_domain.
IPR023393. START-like_dom.
IPR002913. START_lipid-bd_dom.
[Graphical view]
PfamiPF00498. FHA. 1 hit.
PF00225. Kinesin. 1 hit.
PF01852. START. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00240. FHA. 1 hit.
SM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF49879. SSF49879. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
PS50848. START. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9P2P6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MANVQVAVRV RPLSKRETKE GGRIIVEVDG KVAKIRNLKV DNRPDGFGDS
60 70 80 90 100
REKVMAFGFD YCYWSVNPED PQYASQDVVF QDLGMEVLSG VAKGYNICLF
110 120 130 140 150
AYGQTGSGKT YTMLGTPASV GLTPRICEGL FVREKDCASL PSSCRIKVSF
160 170 180 190 200
LEIYNERVRD LLKQSGQKKS YTLRVREHPE MGPYVQGLSQ HVVTNYKQVI
210 220 230 240 250
QLLEEGIANR ITAATHVHEA SSRSHAIFTI HYTQAILENN LPSEMASKIN
260 270 280 290 300
LVDLAGSERA DPSYCKDRIA EGANINKSLV TLGIVISTLA QNSQVFSSCQ
310 320 330 340 350
SLNSSVSNGG DSGILSSPSG TSSGGAPSRR QSYIPYRDSV LTWLLKDSLG
360 370 380 390 400
GNSKTIMVAT VSPAHTSYSE TMSTLRYASS AKNIINKPRV NEDANLKLIR
410 420 430 440 450
ELREEIERLK ALLLSFELRN FSSLSDENLK ELVLQNELKI DQLTKDWTQK
460 470 480 490 500
WNDWQALMEH YSVDINRRRA GVVIDSSLPH LMALEDDVLS TGVVLYHLKE
510 520 530 540 550
GTTKIGRIDS DQEQDIVLQG QWIERDHCTI TSACGVVVLR PARGARCTVN
560 570 580 590 600
GREVTASCRL TQGAVITLGK AQKFRFNHPA EAAVLRQRRQ VGEAAAGRGS
610 620 630 640 650
LEWLDLDGDL AASRLGLSPL LWKERRALEE QCDEDHQTPR DGETSHRAQI
660 670 680 690 700
QQQQSYVEDL RHQILAEEIR AAKELEFDQA WISQQIKENQ QCLLREETWL
710 720 730 740 750
ASLQQQQQED QVAEKELEAS VALDAWLQTD PEIQPSPFVQ SQKRVVHLQL
760 770 780 790 800
LRRHTLRAAE RNVRRKKVSF QLERIIKKQR LLEAQKRLEK LTTLCWLQDD
810 820 830 840 850
STQEPPYQVL SPDATVPRPP CRSKLTSCSS LSPQRLCSKH MPQLHSIFLS
860 870 880 890 900
WDPSTTLPPR PDPTHQTSEK TSSEEHLPQA ASYPARTGCL RKNGLHSSGH
910 920 930 940 950
GQPCTARAAL ARKGASAPDA CLTMSPNSVG IQEMEMGVKQ PHQMVSQGLA
960 970 980 990 1000
SLRKSANKLK PRHEPKIFTS TTQTRGAKGL ADPSHTQAGW RKEGNLGTHK
1010 1020 1030 1040 1050
AAKGASCNSL YPHGPRQTAG HGKAVKTFWT EYKPPSPSRA SKRHQRVLAT
1060 1070 1080 1090 1100
RVRNITKKSS HLPLGSPLKR QQNTRDPDTM VPLTDFSPVM DHSREKDNDL
1110 1120 1130 1140 1150
SDTDSNYSLD SLSCVYAKAL IEPLKPEERK WDFPEPENSE SDDSQLSEDS
1160 1170 1180 1190 1200
LAEKRYQSPK NRLGGNRPTN NRGQPRTRTR ASVRGFTAAS DSDLLAQTHR
1210 1220 1230 1240 1250
SFSLDSLIDA EEELGEDQQE EPFPGSADEI PTETFWHLED SSLPVMDQEA
1260 1270 1280 1290 1300
ICRLGPINYR TAARLDAVLP MSSSFYLDPQ FQPHCELQPH CELQPHCELQ
1310 1320 1330 1340 1350
PHCEQAESQV EPSYSEQADS LQGMQLSRES PLMSMDSWFS CDSKINPSSP
1360 1370 1380 1390 1400
PGIVGSLCPS PDMQEFHSCK GERPGYWPNT EELKPSDAET VLPYSSKLHQ
1410 1420 1430 1440 1450
GSTELLCSAR DEHTASAADT SRLSLWGIQR LIQPGADGTF QGRCIPDMTQ
1460 1470 1480 1490 1500
QGSSEASHNS SVSNVLAASA TTLTHVGSTH ERDWSALQQK YLLELSCPVL
1510 1520 1530 1540 1550
EAIGAPKPAY PYLEEDSGSL AQASSKGGDT LLPVGPRVSS NLNLNNFPVH
1560 1570 1580 1590 1600
LSRIRRLRAE KEQDSLNAKL EGVSDFFSTS EKEASYDETY SADLESLSAS
1610 1620 1630 1640 1650
RSTNAQVFAT ENAIPDSMTE ACEVKQNNLE ECLQSCRKPG LMTSSDEDFF
1660 1670 1680 1690 1700
QKNACHSNVT TATKADHWSQ GWAPLRKNSA VQPGQLSPDS HYPLEEEKTD
1710 1720 1730 1740 1750
CQESSKEAVR RHINVSFALP SGPELYLHSA PWNPLSSSLQ PPLLETFYVT
1760 1770 1780 1790 1800
KSRDALTETA LEIPACREVR VPSPPPREAW GFGHNHQALQ GAYLKNNLPV
1810 1820 1830 1840 1850
LLQNQNSKIA SSQQVTAEIP VDLNTREVIR ESGKCPGNIT EESHDSVYSS
1860 1870 1880 1890 1900
VTQNRHFLPS TSTKVCEFEN QVVILNKKHS FPALEGGEVT AQSCCGASSD
1910 1920 1930 1940 1950
STESGKSLLF RESEAREEEE LDQNTVLRQT INVSLEKDMP GESAVSLKSR
1960 1970 1980 1990 2000
SVDRRVSSPV MVAQGGGPTP KWEGKNETGL LEKGLRPKDS SEEFKLPGTK
2010 2020 2030 2040 2050
PAYERFQLVA CPQERNPSEC KSQEMLNPNR EPSGKKQNKR VNNTDEMARL
2060 2070 2080 2090 2100
IRSVMQLENG ILEIESKQNK QVHASHTPGT DKELVFQDQK EQEKTDHAFR
2110 2120 2130 2140 2150
PDSSGNPLPS KDQPSSPRQT DDTVFRDSEA GAMEVNSIGN HPQVQKITPN
2160 2170 2180 2190 2200
PFRSREGVRE SEPVREHTHP AGSDRPARDI CDSLGKHTTC REFTNTSLHP
2210 2220 2230 2240 2250
QRMKALARAL PLQPRLERSS KNNGQFVKAS ASLKGQPWGL GSLEELETVK
2260 2270 2280 2290 2300
GFQESQVAEH VSSSNQEEPK AQGKVEEMPM QRGGSLQEEN KVTQKFPSLS
2310 2320 2330 2340 2350
QLCRDTFFRQ ETVSPLLSRT EFCTAPLHQD LSNTLPLNSP RWPRRCLHVP
2360 2370 2380 2390 2400
VALGISSLDC VLDLTMLKIH NSPLVTGVEH QDQSTETRSH SPEGNVRGRS
2410 2420 2430 2440 2450
SEAHTAWCGS VRSMAMGSHS QSGVPESIPL GTEDRISAST SPQDHGKDLR
2460 2470 2480 2490 2500
ITLLGFSTSE DFASEAEVAV QKEIRVSSLN KVSSQPEKRV SFSLEEDSDQ
2510 2520 2530 2540 2550
ASKPRQKAEK ETEDVGLTSG VSLAPVSLPR VPSPEPRLLE PSDHASMCLA
2560 2570 2580 2590 2600
ILEEIRQAKA QRKQLHDFVA RGTVLSYCET LLEPECSSRV AGRPQCKQID
2610 2620 2630 2640 2650
QSSSDQTRNE GEAPGFHVAS LSAEAGQIDL LPDERKVQAT SLSADSFESL
2660 2670 2680 2690 2700
PNTETDREPW DPVQAFSHAA PAQDRKRRTG ELRQFAGASE PFICHSSSSE
2710 2720 2730 2740 2750
IIEKKKDATR TPSSADPLAP DSPRSSAPVE EVRRVVSKKV VAALPSQAPY
2760 2770 2780 2790 2800
DDPRVTLHEL SQSVPQETAE GIPPGSQDSS PEHQEPRTLD TTYGEVSDNL
2810 2820 2830 2840 2850
LVTAQGEKTA HFESQSVTCD VQNSTSASGP KQDHVQCPEA STGFEEGRAS
2860 2870 2880 2890 2900
PKQDTILPGA LTRVALEAPT QQCVQCKESV GSGLTEVCRA GSKHSRPIPL
2910 2920 2930 2940 2950
PDQRPSANPG GIGEEAPCRH PREALDGPVF SRNPEGSRTL SPSRGKESRT
2960 2970 2980 2990 3000
LPCRQPCSSQ PVATHAYSSH SSTLLCFRDG DLGKEPFKAA PHTIHPPCVV
3010 3020 3030 3040 3050
PSRAYEMDET GEISRGPDVH LTHGLEPKDV NREFRLTESS TCEPSTVAAV
3060 3070 3080 3090 3100
LSRAQGCRSP SAPDVRTGSF SHSATDGSVG LIGVPEKKVA EKQASTELEA
3110 3120 3130 3140 3150
ASFPAGMYSE PLRQFRDSSV GDQNAQVCQT NPEPPATTQG PHTLDLSEGS
3160 3170 3180 3190 3200
AESKLVVEPQ HECLENTTRC FLEKPQFSTE LRDHNRLDSQ AKFVARLKHT
3210 3220 3230 3240 3250
CSPQEDSPWQ EEEQHRDQAS GGGEGFAQGV NPLPDEDGLD GCQILDAGRE
3260 3270 3280 3290 3300
EVAVAKPPVS KILSQGFKDP ATVSLRQNET PQPAAQRSGH LYTGREQPAP
3310 3320 3330 3340 3350
NHRGSLPVTT IFSGPKHSRS SPTPQFSVVG SSRSLQELNL SVEPPSPTDE
3360 3370 3380 3390 3400
DTQGPNRLWN PHLRGYSSGK SVARTSLQAE DSNQKASSRL DDGTTDHRHL
3410 3420 3430 3440 3450
KPATPPYPMP STLSHMPTPD FTTSWMSGTL EQAQQGKREK LGVQVRPENW
3460 3470 3480 3490 3500
CSQMDKGMLH FGSSDISPYA LPWRPEEPAR ISWKQYMSGS AVDVSCSQKP
3510 3520 3530 3540 3550
QGLTLSNVAR CSSMDNGLED QNSPFHSHLS TYANICDLST THSSTENAQG
3560 3570 3580 3590 3600
SNEAWEVFRG SSSIALGDPH IPTSPEGVAP TSGHDRRPQF RGPSGEADCL
3610 3620 3630 3640 3650
RSKPPLAKGS AAGPVDEIML LYPSEAGCPV GQTRTNTFEQ GTQTLGSRRH
3660 3670 3680 3690 3700
WSSTDISFAQ PEASAVSAFD LASWTSMHNL SLHLSQLLHS TSELLGSLSQ
3710 3720 3730 3740 3750
PDVARREQNT KRDIPDKAPQ ALMMDGSTQT TVDEGSQTDL TLPTLCLQTS
3760 3770 3780 3790 3800
EAEPQGANVI LEGLGSDTST VSQEEGDVPG VPQKREAEET AQKMAQLLYL
3810 3820 3830 3840 3850
QEESTPYKPQ SPSIPSSHLR FQKAPVGQHL PSVSPSVSDA FLPPSSQPEE
3860 3870 3880 3890 3900
SYCLVVSSPS PSSPHSPGLF PSTSEYPGDS RVQKKLGPTS ALFVDRASSP
3910 3920 3930 3940 3950
ILTLSASTQE PGLSPGSLTL SAPSTHPVEG HQKLDSSPDP VDAPRTPMDN
3960 3970 3980 3990 4000
YSQTTDELGG SQRGRSSLQR SNGRSFLELH SPHSPQQSPK LQFSFLGQHP
4010 4020 4030 4040 4050
QQLQPRTTIG VQSRLLPPPL RHRSQRLGNS FVPEKVASPE HCPLSGREPS
4060 4070 4080 4090 4100
QWQSRTENGG ESSASPGEPQ RTLDRPSSWG GLQHLSPCPV SELTDTAGLR
4110 4120 4130 4140 4150
GSALGLPQAC QPEELLCFSC QMCMAPEHQH HSLRDLPVHN KFSNWCGVQK
4160 4170 4180 4190 4200
GSPGGLDMTE EELGASGDLS SEKQEQSPPQ PPNDHSQDSE WSKREQIPLQ
4210 4220 4230 4240 4250
VGAQNLSLSV ELTEAKLHHG FGEADALLQV LQSGTGEALA ADEPVTSTWK
4260 4270 4280 4290 4300
ELYARQKKAI ETLRRERAER LGNFCRTRSL SPQKQLSLLP NKDLFIWDLD
4310 4320 4330 4340 4350
LPSRRREYLQ QLRKDVVETT RSPESVSRSA HTPSDIELML QDYQQAHEEA
4360 4370 4380 4390 4400
KVEIARARDQ LRERTEQEKL RIHQKIISQL LKEEDKLHTL ANSSSLCTSS
4410 4420 4430 4440 4450
NGSLSSGMTS GYNSSPALSG QLQFPENMGH TNLPDSRDVW IGDERGGHSA
4460 4470 4480 4490 4500
VRKNSAYSHR ASLGSCCCSP SSLSSLGTCF SSSYQDLAKH VVDTSMADVM
4510 4520 4530 4540 4550
AACSDNLHNL FSCQATAGWN YQGEEQAVQL YYKVFSPTRH GFLGAGVVSQ
4560 4570 4580 4590 4600
PLSRVWAAVS DPTVWPLYYK PIQTARLHQR VTNSISLVYL VCNTTLCALK
4610 4620 4630 4640 4650
QPRDFCCVCV EAKEGHLSVM AAQSVYDTSM PRPSRKMVRG EILPSAWILQ
4660 4670 4680 4690 4700
PITVEGKEVT RVIYLAQVEL GAPGFPPQLL SSFIKRQPLV IARLASFLGR
Length:4,700
Mass (Da):516,343
Last modified:February 22, 2012 - v3
Checksum:iD422BEE9E5612036
GO
Isoform 2 (identifier: Q9P2P6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     290-292: AQN → GIF
     293-4700: Missing.

Note: No experimental confirmation available.
Show »
Length:292
Mass (Da):32,326
Checksum:i8BDCDCAEEF042674
GO
Isoform 3 (identifier: Q9P2P6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-84: Missing.
     360-435: TVSPAHTSYS...DENLKELVLQ → SEWDARAGPV...SISEKGPWPQ
     436-4700: Missing.

Note: No experimental confirmation available.
Show »
Length:323
Mass (Da):35,159
Checksum:i2981E165492842F6
GO

Sequence cautioni

The sequence CAH18258 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAH18258 differs from that shown. Reason: Erroneous termination at position 2903. Translated as Gln.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti2602S → L in CAH18258 (PubMed:17974005).Curated1
Sequence conflicti2818T → I in CAH18258 (PubMed:17974005).Curated1
Sequence conflicti3633T → A in CAH18258 (PubMed:17974005).Curated1
Sequence conflicti4433 – 4438LPDSRD → IPGIRQ in CAB63725 (PubMed:17974005).Curated6
Sequence conflicti4639R → H in BAA92538 (PubMed:10718198).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_059811835R → C.Corresponds to variant rs12594837dbSNPEnsembl.1
Natural variantiVAR_0372571172R → C.Corresponds to variant rs12594837dbSNPEnsembl.1
Natural variantiVAR_0372581720P → L.Corresponds to variant rs7161810dbSNPEnsembl.1
Natural variantiVAR_0372592205A → V.Corresponds to variant rs16957055dbSNPEnsembl.1
Natural variantiVAR_0372602677R → H.Corresponds to variant rs8030587dbSNPEnsembl.1
Natural variantiVAR_0372612855T → I.Corresponds to variant rs8031218dbSNPEnsembl.1
Natural variantiVAR_0372622869P → S.Corresponds to variant rs11857283dbSNPEnsembl.1
Natural variantiVAR_0372633015R → G.Corresponds to variant rs3742995dbSNPEnsembl.1
Natural variantiVAR_0372643383N → D.1 PublicationCorresponds to variant rs3742993dbSNPEnsembl.1
Natural variantiVAR_0372663469Y → C.Corresponds to variant rs16957061dbSNPEnsembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0295731 – 84Missing in isoform 3. 1 PublicationAdd BLAST84
Alternative sequenceiVSP_029574290 – 292AQN → GIF in isoform 2. 1 Publication3
Alternative sequenceiVSP_029575293 – 4700Missing in isoform 2. 1 PublicationAdd BLAST4408
Alternative sequenceiVSP_029576360 – 435TVSPA…ELVLQ → SEWDARAGPVLGLVLYLRER AMAPVSGMPELDLCWDWYSI SEKGPWPQ in isoform 3. 1 PublicationAdd BLAST76
Alternative sequenceiVSP_029577436 – 4700Missing in isoform 3. 1 PublicationAdd BLAST4265

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122666 mRNA. Translation: BAC85502.1.
AL133579 mRNA. Translation: CAB63725.1.
CR627426 mRNA. Translation: CAH10513.1.
CR749416 mRNA. Translation: CAH18258.1. Sequence problems.
AC018362 Genomic DNA. No translation available.
AC090510 Genomic DNA. No translation available.
AB037721 mRNA. Translation: BAA92538.1.
CCDSiCCDS53935.1. [Q9P2P6-1]
PIRiT43486.
RefSeqiNP_065810.2. NM_020759.2. [Q9P2P6-1]
UniGeneiHs.122061.

Genome annotation databases

EnsembliENST00000290607; ENSP00000290607; ENSG00000159433. [Q9P2P6-1]
GeneIDi57519.
KEGGihsa:57519.
UCSCiuc010udj.3. human. [Q9P2P6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK122666 mRNA. Translation: BAC85502.1.
AL133579 mRNA. Translation: CAB63725.1.
CR627426 mRNA. Translation: CAH10513.1.
CR749416 mRNA. Translation: CAH18258.1. Sequence problems.
AC018362 Genomic DNA. No translation available.
AC090510 Genomic DNA. No translation available.
AB037721 mRNA. Translation: BAA92538.1.
CCDSiCCDS53935.1. [Q9P2P6-1]
PIRiT43486.
RefSeqiNP_065810.2. NM_020759.2. [Q9P2P6-1]
UniGeneiHs.122061.

3D structure databases

ProteinModelPortaliQ9P2P6.
SMRiQ9P2P6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121580. 7 interactors.
IntActiQ9P2P6. 4 interactors.
MINTiMINT-1432918.
STRINGi9606.ENSP00000290607.

PTM databases

iPTMnetiQ9P2P6.
PhosphoSitePlusiQ9P2P6.

Polymorphism and mutation databases

BioMutaiSTARD9.
DMDMi378405232.

Proteomic databases

EPDiQ9P2P6.
MaxQBiQ9P2P6.
PaxDbiQ9P2P6.
PeptideAtlasiQ9P2P6.
PRIDEiQ9P2P6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000290607; ENSP00000290607; ENSG00000159433. [Q9P2P6-1]
GeneIDi57519.
KEGGihsa:57519.
UCSCiuc010udj.3. human. [Q9P2P6-1]

Organism-specific databases

CTDi57519.
GeneCardsiSTARD9.
HGNCiHGNC:19162. STARD9.
HPAiHPA014562.
MIMi614642. gene.
neXtProtiNX_Q9P2P6.
OpenTargetsiENSG00000159433.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0245. Eukaryota.
COG5059. LUCA.
GeneTreeiENSGT00860000133823.
HOGENOMiHOG000169805.
HOVERGENiHBG108517.
InParanoidiQ9P2P6.
KOiK16491.
OMAiSDQEQDI.
OrthoDBiEOG091G00MR.
PhylomeDBiQ9P2P6.
TreeFamiTF332626.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000159433-MONOMER.

Miscellaneous databases

ChiTaRSiSTARD9. human.
GenomeRNAii57519.
PROiQ9P2P6.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000159433.
CleanExiHS_STARD9.
ExpressionAtlasiQ9P2P6. baseline and differential.
GenevisibleiQ9P2P6. HS.

Family and domain databases

Gene3Di2.60.200.20. 1 hit.
3.30.530.20. 1 hit.
3.40.850.10. 1 hit.
InterProiIPR000253. FHA_dom.
IPR019821. Kinesin_motor_CS.
IPR001752. Kinesin_motor_dom.
IPR027417. P-loop_NTPase.
IPR008984. SMAD_FHA_domain.
IPR023393. START-like_dom.
IPR002913. START_lipid-bd_dom.
[Graphical view]
PfamiPF00498. FHA. 1 hit.
PF00225. Kinesin. 1 hit.
PF01852. START. 1 hit.
[Graphical view]
PRINTSiPR00380. KINESINHEAVY.
SMARTiSM00240. FHA. 1 hit.
SM00129. KISc. 1 hit.
[Graphical view]
SUPFAMiSSF49879. SSF49879. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiPS00411. KINESIN_MOTOR_1. 1 hit.
PS50067. KINESIN_MOTOR_2. 1 hit.
PS50848. START. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSTAR9_HUMAN
AccessioniPrimary (citable) accession number: Q9P2P6
Secondary accession number(s): Q68DG2
, Q6AI01, Q6ZWK0, Q9UF70
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: February 22, 2012
Last modified: November 30, 2016
This is version 120 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.