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Protein

KAT8 regulatory NSL complex subunit 3

Gene

KANSL3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.1 Publication

GO - Biological processi

  • histone H4-K16 acetylation Source: UniProtKB
  • histone H4-K5 acetylation Source: UniProtKB
  • histone H4-K8 acetylation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator

Enzyme and pathway databases

ReactomeiR-HSA-3214847. HATs acetylate histones.

Protein family/group databases

ESTHERihuman-KANSL3. NLS3-Tex30.

Names & Taxonomyi

Protein namesi
Recommended name:
KAT8 regulatory NSL complex subunit 3
Alternative name(s):
NSL complex protein NSL3
Non-specific lethal 3 homolog
Serum inhibited-related protein
Testis development protein PRTD
Gene namesi
Name:KANSL3
Synonyms:KIAA1310, NSL3, PRTD, SI1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:25473. KANSL3.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162393058.

Polymorphism and mutation databases

BioMutaiKANSL3.
DMDMi147646907.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 904904KAT8 regulatory NSL complex subunit 3PRO_0000416242Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei523 – 5231PhosphoserineCombined sources
Modified residuei536 – 5361PhosphoserineBy similarity
Modified residuei540 – 5401PhosphoserineCombined sources
Modified residuei773 – 7731PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9P2N6.
MaxQBiQ9P2N6.
PaxDbiQ9P2N6.
PeptideAtlasiQ9P2N6.
PRIDEiQ9P2N6.

PTM databases

iPTMnetiQ9P2N6.
PhosphoSiteiQ9P2N6.

Expressioni

Gene expression databases

BgeeiQ9P2N6.
CleanExiHS_KIAA1310.
ExpressionAtlasiQ9P2N6. baseline and differential.
GenevisibleiQ9P2N6. HS.

Organism-specific databases

HPAiHPA035017.
HPA035018.
HPA041280.

Interactioni

Subunit structurei

Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.2 Publications

Protein-protein interaction databases

BioGridi120811. 9 interactions.
IntActiQ9P2N6. 10 interactions.
MINTiMINT-1421538.
STRINGi9606.ENSP00000396749.

Structurei

3D structure databases

ProteinModelPortaliQ9P2N6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi700 – 76667Ser-richAdd
BLAST

Phylogenomic databases

eggNOGiKOG3253. Eukaryota.
ENOG410XSH5. LUCA.
GeneTreeiENSGT00390000007636.
HOVERGENiHBG062095.
InParanoidiQ9P2N6.
KOiK16719.
OMAiSVNWDTK.
PhylomeDBiQ9P2N6.
TreeFamiTF323466.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR026555. NSL3/Tex30.
[Graphical view]
PANTHERiPTHR13136. PTHR13136. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequences (8)i

Sequence statusi: Complete.

This entry describes 8 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9P2N6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAHRGGERDF QTSARRMGTS LLFQLSVHER ELDLVFLDHS YAKPWSAHPD
60 70 80 90 100
ASSARPTRML FVTPRRQHES TIESDVPIDV ETVTSTPMPL YDNQKARSVM
110 120 130 140 150
NECERHVIFA RTDADAPPPP EDWEEHVNRT GWTMAQNKLF NKILKALQSD
160 170 180 190 200
RLARLANEGA CNEPVLRRVA VDKCARRVRQ ALASVSWDTK LIQWLHTTLV
210 220 230 240 250
ETLSLPMLAA YLDALQTLKG KIPTLIDRML VSSNTKTGAA GAEALSLLLK
260 270 280 290 300
RPWDPAVGVL SHNKPSKLPG SPLILIASSG PSSSVFPTSR RHRFWQSQLS
310 320 330 340 350
CLGKVIPVAT HLLNNGSGVG VLQCLEHMIG AVRSKVLEIH SHFPHKPIIL
360 370 380 390 400
IGWNTGALVA CHVSVMEYVT AVVCLGFPLL TVDGPRGDVD DPLLDMKTPV
410 420 430 440 450
LFVIGQNSLQ CHPEAMEDFR EKIRAENSLV VVGGADDNLR ISKAKKKSEG
460 470 480 490 500
LTQSMVDRCI QDEIVDFLTG VLTRAEGHMG SEPRDQDAEK KKKPRDVARR
510 520 530 540 550
DLAFEVPERG SRPASPAAKL PASPSGSEDL SSVSSSPTSS PKTKVTTVTS
560 570 580 590 600
AQKSSQIGSS QLLKRHVQRT EAVLTHKQAQ AQFAAFLKQN MLVRKALPPG
610 620 630 640 650
TSSCLFVPIS SEPPEEGEKE DLRVQLKRHH PSSPLPGSKT SKRPKIKVSL
660 670 680 690 700
ISQGDTAGGP CAPSQGSAPE AAGGKPITMT LGQASAGAKE LTGLLTTAKS
710 720 730 740 750
SSSEGGVSAS PVPSVVSSST APSALHTLQS RLVATSPGSS LPGATSASSL
760 770 780 790 800
LQGLSFSLQD ISSKTSGLPA NPSPGPAPQA TSVKLPTPMQ SLGAITTGTS
810 820 830 840 850
TIVRTIPVAT TLSSLGATPG GKPTAIHQLL TNGGLAKLAS SLPGLAQISN
860 870 880 890 900
QASGLKVPTT ITLTLRGQPS RITTLSPMGS GAAPSEESSS QVLPSSSQRL

PPAP
Length:904
Mass (Da):95,992
Last modified:May 15, 2007 - v2
Checksum:i698DD46EC443B5DD
GO
Isoform 2 (identifier: Q9P2N6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     781-904: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.
Show »
Length:780
Mass (Da):83,673
Checksum:iFDE372433A0CDDC7
GO
Isoform 3 (identifier: Q9P2N6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     581-606: Missing.

Show »
Length:878
Mass (Da):93,170
Checksum:i5D9DD9A62F3A20FA
GO
Isoform 4 (identifier: Q9P2N6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-87: Missing.
     581-606: Missing.

Show »
Length:791
Mass (Da):83,296
Checksum:iE77BB055740C1F91
GO
Isoform 5 (identifier: Q9P2N6-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-87: Missing.
     581-606: Missing.
     671-672: Missing.

Note: No experimental confirmation available.
Show »
Length:789
Mass (Da):83,154
Checksum:iA3D9541D40C75FD0
GO
Isoform 6 (identifier: Q9P2N6-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-112: Missing.
     113-129: DADAPPPPEDWEEHVNR → MTLPHCHRLMLTHHLFW
     581-606: Missing.
     671-672: Missing.

Note: No experimental confirmation available.
Show »
Length:764
Mass (Da):80,362
Checksum:i8BDC155A0AC701FB
GO
Isoform 7 (identifier: Q9P2N6-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-87: Missing.
     222-228: IPTLIDR → VILTFCG
     229-904: Missing.

Note: No experimental confirmation available.
Show »
Length:141
Mass (Da):16,016
Checksum:i0E8A108B46959AF7
GO
Isoform 8 (identifier: Q9P2N6-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-87: Missing.
     581-606: Missing.
     637-643: GSKTSKR → VYSWFHH
     644-904: Missing.

Note: No experimental confirmation available.
Show »
Length:530
Mass (Da):58,199
Checksum:i018418758112918F
GO

Sequence cautioni

The sequence AAH15469.1 differs from that shown.Contaminating sequence. Potential poly-A sequence.Curated
The sequence AAI27821.1 differs from that shown.Contaminating sequence. Sequence of unknown origin in the C-terminal part.Curated
The sequence BAA92548.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti529 – 5291D → G in BAA91437 (PubMed:14702039).Curated
Sequence conflicti640 – 6401T → I in AAG33852 (Ref. 2) Curated
Sequence conflicti640 – 6401T → I in BAB14688 (PubMed:14702039).Curated
Sequence conflicti660 – 6601P → S in AAG33852 (Ref. 2) Curated
Sequence conflicti660 – 6601P → S in BAB14688 (PubMed:14702039).Curated
Sequence conflicti667 – 6671S → C in AAG33852 (Ref. 2) Curated
Sequence conflicti667 – 6671S → C in BAB14688 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti707 – 7071V → I.
Corresponds to variant rs34406082 [ dbSNP | Ensembl ].
VAR_032268

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 112112Missing in isoform 6. 1 PublicationVSP_025324Add
BLAST
Alternative sequencei1 – 8787Missing in isoform 4, isoform 5, isoform 7 and isoform 8. 3 PublicationsVSP_025325Add
BLAST
Alternative sequencei113 – 12917DADAP…EHVNR → MTLPHCHRLMLTHHLFW in isoform 6. 1 PublicationVSP_025326Add
BLAST
Alternative sequencei222 – 2287IPTLIDR → VILTFCG in isoform 7. 1 PublicationVSP_025327
Alternative sequencei229 – 904676Missing in isoform 7. 1 PublicationVSP_025328Add
BLAST
Alternative sequencei581 – 60626Missing in isoform 3, isoform 4, isoform 5, isoform 6 and isoform 8. 4 PublicationsVSP_025329Add
BLAST
Alternative sequencei637 – 6437GSKTSKR → VYSWFHH in isoform 8. 1 PublicationVSP_025330
Alternative sequencei644 – 904261Missing in isoform 8. 1 PublicationVSP_025331Add
BLAST
Alternative sequencei671 – 6722Missing in isoform 5 and isoform 6. 2 PublicationsVSP_025332
Alternative sequencei781 – 904124Missing in isoform 2. 1 PublicationVSP_025333Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY050169 mRNA. Translation: AAL13159.1.
AF311326 mRNA. Translation: AAG33852.1.
AB037731 mRNA. Translation: BAA92548.1. Different initiation.
AK000943 mRNA. Translation: BAA91437.1.
AK023813 mRNA. Translation: BAB14688.1.
AC079754 Genomic DNA. Translation: AAX88890.1.
CH471207 Genomic DNA. Translation: EAW71349.1.
CH471207 Genomic DNA. Translation: EAW71350.1.
CH471207 Genomic DNA. Translation: EAW71352.1.
CH471207 Genomic DNA. Translation: EAW71357.1.
CH471207 Genomic DNA. Translation: EAW71358.1.
BC015469 mRNA. Translation: AAH15469.1. Sequence problems.
BC032746 mRNA. Translation: AAH32746.1.
BC051763 mRNA. Translation: AAH51763.1.
BC063792 mRNA. Translation: AAH63792.1.
BC127820 mRNA. Translation: AAI27821.1. Sequence problems.
AL136849 mRNA. Translation: CAB66783.2.
CCDSiCCDS46361.1. [Q9P2N6-3]
RefSeqiNP_001108488.1. NM_001115016.2. [Q9P2N6-3]
XP_005264041.1. XM_005263984.1. [Q9P2N6-1]
UniGeneiHs.516341.

Genome annotation databases

EnsembliENST00000420155; ENSP00000414426; ENSG00000114982. [Q9P2N6-2]
ENST00000431828; ENSP00000396749; ENSG00000114982. [Q9P2N6-3]
GeneIDi55683.
KEGGihsa:55683.
UCSCiuc002swn.6. human. [Q9P2N6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY050169 mRNA. Translation: AAL13159.1.
AF311326 mRNA. Translation: AAG33852.1.
AB037731 mRNA. Translation: BAA92548.1. Different initiation.
AK000943 mRNA. Translation: BAA91437.1.
AK023813 mRNA. Translation: BAB14688.1.
AC079754 Genomic DNA. Translation: AAX88890.1.
CH471207 Genomic DNA. Translation: EAW71349.1.
CH471207 Genomic DNA. Translation: EAW71350.1.
CH471207 Genomic DNA. Translation: EAW71352.1.
CH471207 Genomic DNA. Translation: EAW71357.1.
CH471207 Genomic DNA. Translation: EAW71358.1.
BC015469 mRNA. Translation: AAH15469.1. Sequence problems.
BC032746 mRNA. Translation: AAH32746.1.
BC051763 mRNA. Translation: AAH51763.1.
BC063792 mRNA. Translation: AAH63792.1.
BC127820 mRNA. Translation: AAI27821.1. Sequence problems.
AL136849 mRNA. Translation: CAB66783.2.
CCDSiCCDS46361.1. [Q9P2N6-3]
RefSeqiNP_001108488.1. NM_001115016.2. [Q9P2N6-3]
XP_005264041.1. XM_005263984.1. [Q9P2N6-1]
UniGeneiHs.516341.

3D structure databases

ProteinModelPortaliQ9P2N6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120811. 9 interactions.
IntActiQ9P2N6. 10 interactions.
MINTiMINT-1421538.
STRINGi9606.ENSP00000396749.

Protein family/group databases

ESTHERihuman-KANSL3. NLS3-Tex30.

PTM databases

iPTMnetiQ9P2N6.
PhosphoSiteiQ9P2N6.

Polymorphism and mutation databases

BioMutaiKANSL3.
DMDMi147646907.

Proteomic databases

EPDiQ9P2N6.
MaxQBiQ9P2N6.
PaxDbiQ9P2N6.
PeptideAtlasiQ9P2N6.
PRIDEiQ9P2N6.

Protocols and materials databases

DNASUi55683.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000420155; ENSP00000414426; ENSG00000114982. [Q9P2N6-2]
ENST00000431828; ENSP00000396749; ENSG00000114982. [Q9P2N6-3]
GeneIDi55683.
KEGGihsa:55683.
UCSCiuc002swn.6. human. [Q9P2N6-1]

Organism-specific databases

CTDi55683.
GeneCardsiKANSL3.
HGNCiHGNC:25473. KANSL3.
HPAiHPA035017.
HPA035018.
HPA041280.
neXtProtiNX_Q9P2N6.
PharmGKBiPA162393058.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3253. Eukaryota.
ENOG410XSH5. LUCA.
GeneTreeiENSGT00390000007636.
HOVERGENiHBG062095.
InParanoidiQ9P2N6.
KOiK16719.
OMAiSVNWDTK.
PhylomeDBiQ9P2N6.
TreeFamiTF323466.

Enzyme and pathway databases

ReactomeiR-HSA-3214847. HATs acetylate histones.

Miscellaneous databases

ChiTaRSiKANSL3. human.
GeneWikiiFLJ10081.
GenomeRNAii55683.
PROiQ9P2N6.

Gene expression databases

BgeeiQ9P2N6.
CleanExiHS_KIAA1310.
ExpressionAtlasiQ9P2N6. baseline and differential.
GenevisibleiQ9P2N6. HS.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR026555. NSL3/Tex30.
[Graphical view]
PANTHERiPTHR13136. PTHR13136. 1 hit.
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of a gene which is inhibited by serum."
    Tan D., Lai J., Yu M., He Y., Qian W., Jiang Y.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4).
  2. "A novel gene related to testis development (PRTD)."
    Cheng L.J., Li J.M., Sha J.H.
    Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 6).
    Tissue: Testis.
  3. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
    DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Brain.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5 AND 8).
    Tissue: Embryo and Placenta.
  5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 7), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 75-904 (ISOFORM 1).
    Tissue: Duodenum, PNS and Uterus.
  8. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 645-898.
    Tissue: Testis.
  9. "Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila."
    Mendjan S., Taipale M., Kind J., Holz H., Gebhardt P., Schelder M., Vermeulen M., Buscaino A., Duncan K., Mueller J., Wilm M., Stunnenberg H.G., Saumweber H., Akhtar A.
    Mol. Cell 21:811-823(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE NSL COMPLEX.
  10. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-523 AND SER-540, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  12. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  13. "Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex."
    Cai Y., Jin J., Swanson S.K., Cole M.D., Choi S.H., Florens L., Washburn M.P., Conaway J.W., Conaway R.C.
    J. Biol. Chem. 285:4268-4272(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION IN HISTONE H4 ACETYLATION, IDENTIFICATION IN NSL COMPLEX, SUBCELLULAR LOCATION.
  14. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-773, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma and Erythroleukemia.

Entry informationi

Entry nameiKANL3_HUMAN
AccessioniPrimary (citable) accession number: Q9P2N6
Secondary accession number(s): A1L184
, D3DXH3, D3DXH4, Q05BU4, Q6P3X2, Q6PJH6, Q86T19, Q96L64, Q9H0C9, Q9H8C9, Q9HAP8, Q9NWE5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: July 6, 2016
This is version 99 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.