Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9P2G1

- AKIB1_HUMAN

UniProt

Q9P2G1 - AKIB1_HUMAN

Protein

Ankyrin repeat and IBR domain-containing protein 1

Gene

ANKIB1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 118 (01 Oct 2014)
      Sequence version 3 (24 Jul 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri333 – 38351RING-type 1; atypicalPROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri402 – 47877IBR-type; degenerateAdd
    BLAST
    Zinc fingeri519 – 54830RING-type 2; degeneratePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. protein binding Source: IntAct
    2. zinc ion binding Source: InterPro

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ankyrin repeat and IBR domain-containing protein 1
    Gene namesi
    Name:ANKIB1
    Synonyms:KIAA1386
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 7

    Organism-specific databases

    HGNCiHGNC:22215. ANKIB1.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134941469.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed
    Chaini2 – 10891088Ankyrin repeat and IBR domain-containing protein 1PRO_0000066892Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Lipidationi2 – 21N-myristoyl glycine1 Publication
    Modified residuei737 – 7371Phosphoserine3 Publications

    Keywords - PTMi

    Lipoprotein, Myristate, Phosphoprotein

    Proteomic databases

    MaxQBiQ9P2G1.
    PaxDbiQ9P2G1.
    PRIDEiQ9P2G1.

    PTM databases

    PhosphoSiteiQ9P2G1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9P2G1.
    BgeeiQ9P2G1.
    CleanExiHS_ANKIB1.
    GenevestigatoriQ9P2G1.

    Organism-specific databases

    HPAiHPA019358.
    HPA021780.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    NR4A1P227362EBI-2687890,EBI-721550

    Protein-protein interaction databases

    BioGridi119973. 4 interactions.
    IntActiQ9P2G1. 2 interactions.
    STRINGi9606.ENSP00000265742.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9P2G1.
    SMRiQ9P2G1. Positions 30-197, 225-731.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati45 – 7430ANK 1Add
    BLAST
    Repeati144 – 17330ANK 2Add
    BLAST
    Repeati851 – 87020UIMAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili575 – 64066Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the RBR family.Curated
    Contains 2 ANK repeats.PROSITE-ProRule annotation
    Contains 1 IBR-type zinc finger.Curated
    Contains 2 RING-type zinc fingers.PROSITE-ProRule annotation
    Contains 1 UIM (ubiquitin-interacting motif) repeat.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri333 – 38351RING-type 1; atypicalPROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri402 – 47877IBR-type; degenerateAdd
    BLAST
    Zinc fingeri519 – 54830RING-type 2; degeneratePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    ANK repeat, Coiled coil, Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG327249.
    HOGENOMiHOG000033880.
    HOVERGENiHBG083226.
    InParanoidiQ9P2G1.
    KOiK11967.
    OMAiNNPAIKW.
    OrthoDBiEOG7T7GSP.
    PhylomeDBiQ9P2G1.
    TreeFamiTF331104.

    Family and domain databases

    Gene3Di1.25.40.20. 1 hit.
    3.30.40.10. 1 hit.
    InterProiIPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR003903. Ubiquitin-int_motif.
    IPR002867. Znf_C6HC.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PfamiPF00023. Ank. 1 hit.
    PF12796. Ank_2. 1 hit.
    PF01485. IBR. 2 hits.
    [Graphical view]
    SMARTiSM00248. ANK. 2 hits.
    SM00647. IBR. 2 hits.
    SM00184. RING. 2 hits.
    SM00726. UIM. 1 hit.
    [Graphical view]
    SUPFAMiSSF48403. SSF48403. 1 hit.
    PROSITEiPS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 2 hits.
    PS50330. UIM. 1 hit.
    PS50089. ZF_RING_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9P2G1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGNTTTKFRK ALINGDENLA CQIYENNPQL KESLDPNTSY GEPYQHNTPL     50
    HYAARHGMNK ILGTFLGRDG NPNKRNVHNE TSMHLLCMGP QIMISEGALH 100
    PRLARPTEDD FRRADCLQMI LKWKGAKLDQ GEYERAAIDA VDNKKNTPLH 150
    YAAASGMKAC VELLVKHGGD LFAENENKDT PCDCAEKQHH KDLALNLESQ 200
    MVFSRDPEAE EIEAEYAALD KREPYEGLRP QDLRRLKDML IVETADMLQA 250
    PLFTAEALLR AHDWDREKLL EAWMSNPENC CQRSGVQMPT PPPSGYNAWD 300
    TLPSPRTPRT TRSSVTSPDE ISLSPGDLDT SLCDICMCSI SVFEDPVDMP 350
    CGHDFCRGCW ESFLNLKIQE GEAHNIFCPA YDCFQLVPVD IIESVVSKEM 400
    DKRYLQFDIK AFVENNPAIK WCPTPGCDRA VRLTKQGSNT SGSDTLSFPL 450
    LRAPAVDCGK GHLFCWECLG EAHEPCDCQT WKNWLQKITE MKPEELVGVS 500
    EAYEDAANCL WLLTNSKPCA NCKSPIQKNE GCNHMQCAKC KYDFCWICLE 550
    EWKKHSSSTG GYYRCTRYEV IQHVEEQSKE MTVEAEKKHK RFQELDRFMH 600
    YYTRFKNHEH SYQLEQRLLK TAKEKMEQLS RALKETEGGC PDTTFIEDAV 650
    HVLLKTRRIL KCSYPYGFFL EPKSTKKEIF ELMQTDLEMV TEDLAQKVNR 700
    PYLRTPRHKI IKAACLVQQK RQEFLASVAR GVAPADSPEA PRRSFAGGTW 750
    DWEYLGFASP EEYAEFQYRR RHRQRRRGDV HSLLSNPPDP DEPSESTLDI 800
    PEGGSSSRRP GTSVVSSASM SVLHSSSLRD YTPASRSENQ DSLQALSSLD 850
    EDDPNILLAI QLSLQESGLA LDEETRDFLS NEASLGAIGT SLPSRLDSVP 900
    RNTDSPRAAL SSSELLELGD SLMRLGAEND PFSTDTLSSH PLSEARSDFC 950
    PSSSDPDSAG QDPNINDNLL GNIMAWFHDM NPQSIALIPP ATTEISADSQ 1000
    LPCIKDGSEG VKDVELVLPE DSMFEDASVS EGRGTQIEEN PLEENILAGE 1050
    AASQAGDSGN EAANRGDGSD VSSQTPQTSS DWLEQVHLV 1089
    Length:1,089
    Mass (Da):122,002
    Last modified:July 24, 2007 - v3
    Checksum:i038570CD3887FF44
    GO

    Sequence cautioni

    The sequence AAH63861.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAA91537.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAA92624.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti929 – 9291N → S in BAA91537. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti1016 – 10161L → M.3 Publications
    Corresponds to variant rs38794 [ dbSNP | Ensembl ].
    VAR_030862

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB037807 mRNA. Translation: BAA92624.1. Different initiation.
    AC000118 Genomic DNA. No translation available.
    AC000120 Genomic DNA. No translation available.
    AC004539 Genomic DNA. No translation available.
    AC007566 Genomic DNA. No translation available.
    BC063861 mRNA. Translation: AAH63861.1. Different initiation.
    BC073893 mRNA. Translation: AAH73893.1.
    AK001179 mRNA. Translation: BAA91537.1. Different initiation.
    AL137349 mRNA. Translation: CAB70704.1.
    CCDSiCCDS47639.1.
    PIRiT46423.
    RefSeqiNP_061877.1. NM_019004.1.
    XP_005250514.1. XM_005250457.1.
    UniGeneiHs.83293.

    Genome annotation databases

    EnsembliENST00000265742; ENSP00000265742; ENSG00000001629.
    GeneIDi54467.
    KEGGihsa:54467.
    UCSCiuc003ulw.2. human.

    Polymorphism databases

    DMDMi158937428.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB037807 mRNA. Translation: BAA92624.1 . Different initiation.
    AC000118 Genomic DNA. No translation available.
    AC000120 Genomic DNA. No translation available.
    AC004539 Genomic DNA. No translation available.
    AC007566 Genomic DNA. No translation available.
    BC063861 mRNA. Translation: AAH63861.1 . Different initiation.
    BC073893 mRNA. Translation: AAH73893.1 .
    AK001179 mRNA. Translation: BAA91537.1 . Different initiation.
    AL137349 mRNA. Translation: CAB70704.1 .
    CCDSi CCDS47639.1.
    PIRi T46423.
    RefSeqi NP_061877.1. NM_019004.1.
    XP_005250514.1. XM_005250457.1.
    UniGenei Hs.83293.

    3D structure databases

    ProteinModelPortali Q9P2G1.
    SMRi Q9P2G1. Positions 30-197, 225-731.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 119973. 4 interactions.
    IntActi Q9P2G1. 2 interactions.
    STRINGi 9606.ENSP00000265742.

    PTM databases

    PhosphoSitei Q9P2G1.

    Polymorphism databases

    DMDMi 158937428.

    Proteomic databases

    MaxQBi Q9P2G1.
    PaxDbi Q9P2G1.
    PRIDEi Q9P2G1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000265742 ; ENSP00000265742 ; ENSG00000001629 .
    GeneIDi 54467.
    KEGGi hsa:54467.
    UCSCi uc003ulw.2. human.

    Organism-specific databases

    CTDi 54467.
    GeneCardsi GC07P091875.
    H-InvDB HIX0006840.
    HGNCi HGNC:22215. ANKIB1.
    HPAi HPA019358.
    HPA021780.
    neXtProti NX_Q9P2G1.
    PharmGKBi PA134941469.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG327249.
    HOGENOMi HOG000033880.
    HOVERGENi HBG083226.
    InParanoidi Q9P2G1.
    KOi K11967.
    OMAi NNPAIKW.
    OrthoDBi EOG7T7GSP.
    PhylomeDBi Q9P2G1.
    TreeFami TF331104.

    Miscellaneous databases

    GenomeRNAii 54467.
    NextBioi 56745.
    PROi Q9P2G1.

    Gene expression databases

    ArrayExpressi Q9P2G1.
    Bgeei Q9P2G1.
    CleanExi HS_ANKIB1.
    Genevestigatori Q9P2G1.

    Family and domain databases

    Gene3Di 1.25.40.20. 1 hit.
    3.30.40.10. 1 hit.
    InterProi IPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR003903. Ubiquitin-int_motif.
    IPR002867. Znf_C6HC.
    IPR001841. Znf_RING.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    Pfami PF00023. Ank. 1 hit.
    PF12796. Ank_2. 1 hit.
    PF01485. IBR. 2 hits.
    [Graphical view ]
    SMARTi SM00248. ANK. 2 hits.
    SM00647. IBR. 2 hits.
    SM00184. RING. 2 hits.
    SM00726. UIM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48403. SSF48403. 1 hit.
    PROSITEi PS50297. ANK_REP_REGION. 1 hit.
    PS50088. ANK_REPEAT. 2 hits.
    PS50330. UIM. 1 hit.
    PS50089. ZF_RING_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
      DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT MET-1016.
      Tissue: Brain.
    2. "The DNA sequence of human chromosome 7."
      Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L.
      , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K.
      Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Skin and Uterus.
    4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 540-1089, VARIANT MET-1016.
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 549-1089, VARIANT MET-1016.
      Tissue: Testis.
    6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-737, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    7. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-737, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Platelet.
    8. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
      Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-737, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    10. "Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system."
      Suzuki T., Moriya K., Nagatoshi K., Ota Y., Ezure T., Ando E., Tsunasawa S., Utsumi T.
      Proteomics 10:1780-1793(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: MYRISTOYLATION AT GLY-2.

    Entry informationi

    Entry nameiAKIB1_HUMAN
    AccessioniPrimary (citable) accession number: Q9P2G1
    Secondary accession number(s): Q6GMS4
    , Q6P3S9, Q9NTD7, Q9NW49
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 4, 2005
    Last sequence update: July 24, 2007
    Last modified: October 1, 2014
    This is version 118 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Caution

    Lacks one Cys residue in the IBR-type zinc finger domain that is one of the conserved features of the family.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 7
      Human chromosome 7: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3