Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

BAH and coiled-coil domain-containing protein 1

Gene

BAHCC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciZFISH:ENSG00000171282-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
BAH and coiled-coil domain-containing protein 1
Alternative name(s):
Bromo adjacent homology domain-containing protein 2
Short name:
BAH domain-containing protein 2
Gene namesi
Name:BAHCC1
Synonyms:BAHD2, KIAA1447
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:29279. BAHCC1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA128394719.

Polymorphism and mutation databases

BioMutaiBAHCC1.
DMDMi205371795.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003121181 – 2608BAH and coiled-coil domain-containing protein 1Add BLAST2608

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei222N6-acetyllysineCombined sources1
Modified residuei2243PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9P281.
MaxQBiQ9P281.
PaxDbiQ9P281.
PeptideAtlasiQ9P281.
PRIDEiQ9P281.

PTM databases

iPTMnetiQ9P281.
PhosphoSitePlusiQ9P281.

Expressioni

Gene expression databases

CleanExiHS_BAHCC1.

Organism-specific databases

HPAiHPA023386.

Interactioni

Protein-protein interaction databases

BioGridi121648. 10 interactors.
IntActiQ9P281. 5 interactors.
STRINGi9606.ENSP00000303486.

Structurei

3D structure databases

ProteinModelPortaliQ9P281.
SMRiQ9P281.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2482 – 2602BAHPROSITE-ProRule annotationAdd BLAST121

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1397 – 1442Sequence analysisAdd BLAST46

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi788 – 1028Pro-richAdd BLAST241
Compositional biasi2315 – 2349Ser-richAdd BLAST35

Sequence similaritiesi

Contains 1 BAH domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IUIU. Eukaryota.
ENOG410ZM6U. LUCA.
HOGENOMiHOG000095172.
HOVERGENiHBG107492.
InParanoidiQ9P281.
PhylomeDBiQ9P281.

Family and domain databases

InterProiIPR001025. BAH_dom.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
[Graphical view]
SMARTiSM00439. BAH. 1 hit.
[Graphical view]
PROSITEiPS51038. BAH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9P281-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGRDFAPPP HLLSERGSLG HRSAAAAARL APAGPAAQPP AHFQPGKYFP
60 70 80 90 100
SPLPMASHTA SSRLMGSSPA SSFMGSFLTS SLGSAASTHP SGPSSSPPEQ
110 120 130 140 150
AYRGSHPTTS QIWFSHSHEA PGYPRFSGSL ASTFLPVSHL DHHGNSNVLY
160 170 180 190 200
GQHRFYGTQK DNFYLRNLPP QPTLLPANHN FPSVARAAPA HPMGSCSRDR
210 220 230 240 250
DRGEAGSLQK GPKDFDRFLV GKELGREKAG KAAEGKERPA AEEDGGKERH
260 270 280 290 300
KLVLPVPADG HCREGGPAPR GACEGRPKHL TSCLLNTKVL NGEMGRAALA
310 320 330 340 350
SCAGGMLGRP GTGVVTSGRC AKEAAGPPEP GPAFSECLER RQMLHHTASY
360 370 380 390 400
AGPPPPLSTA AGSFPCLQLH GGPDGLCPLQ DKAPRDLKAS GPTFVPSVGH
410 420 430 440 450
LADKGRPFQA AEACAVAGEG KDRHLEGTMA PDHAAPYGVS YAHLKAEGKG
460 470 480 490 500
ERRPGGFEAA LNPRLKGLDY LSSAGPEASF PGLPKSGLDK SGYFELPTSS
510 520 530 540 550
QDCARPGHQD PLGGKAPQAC CTLDKTVGKE APAGPPGAQK VARIRHQQHL
560 570 580 590 600
MAAEVEQGGI GAEAKRKSLE LASLGYSGPH LPPWGVQAGQ GTAMAISEER
610 620 630 640 650
KAGAYLDPFG SGLQQAALLP QELPAPPDEV SAMKNLLKYS SQALVVGQKA
660 670 680 690 700
PLVGLGGLKA SCIQQEAKFL SSKGPGQSER PDCARSREHD TTHGDGEVRQ
710 720 730 740 750
PPVGIAVALA RQKDTVSRSE AAYGTNTARQ GRAAPAFKGG GGPRSTHALD
760 770 780 790 800
LEAEEERTRL CDDRLGLASR ELLLQDSKDR VEFARIHPPS SCPGDLAPHL
810 820 830 840 850
MMQSGQLGGD PAPHTHPHPP WLPRTRSPSL WMGGHSYGLG HPALHQNLPP
860 870 880 890 900
GFPASVAGPV PSVFPLPQDA PTQLVILPSE PTPHSAPHAL ADVMDQASLW
910 920 930 940 950
PPMYGGRGPA SHMQHPGQLP VYSRPQLLRQ QELYALQQQR AAQFQRKPED
960 970 980 990 1000
QHLDLEEPAQ EKAPKSTHKP VALTPTAPGA PSPAAGPTKL PPCCHPPDPK
1010 1020 1030 1040 1050
PPASSPTPPP RPSAPCTLNV CPASSPGPGS RVRSAEEKNG EGQQSTADII
1060 1070 1080 1090 1100
TSEPDLPPGY LRPMAGLGFS LPSDVHSSNL EDPETMQTTA PGAQPEPTRT
1110 1120 1130 1140 1150
FLPGEPPPCS PRSLEEPGLL SGAREATQDL AATPYPTERG PQGKAADPSP
1160 1170 1180 1190 1200
LEGLQELQCA ALLEAGGPEA TGQAHSTQGG AREERSREEG EQGPSSGASS
1210 1220 1230 1240 1250
QVLEQRAGSP GALEDEGEQP APEEDELEED ELGQQSMEDS EEDCGGAPDN
1260 1270 1280 1290 1300
SHPPRALPGL DALVAATINL GDLPSDSPPD PQPPAASGPP STVPLPHSSG
1310 1320 1330 1340 1350
IHGIALLSEL ADLAIQRQRS ERTVPEEEED VLAFNLQHLA TLATAWSLVE
1360 1370 1380 1390 1400
AAGLDSSTAP AQPPTANPCS GPRLTPRMQI LQRKDTWTPK TKPVCPLKAA
1410 1420 1430 1440 1450
IDRLDTQEVG MRVRLAELQR RYKEKQRELA RLQRKHDHER DESSRSPARR
1460 1470 1480 1490 1500
GPGRPRKRKH SSSLPAPRPT GPLPRSDGKK VKAVRTSLGL LCAELRGGSG
1510 1520 1530 1540 1550
GEPAKKRSKL ERSVYAGLQT ASVEKAQCKK SSCQGGLAPS VAHRVAQLKP
1560 1570 1580 1590 1600
KVKSKGLPTG LSSFQQKEAT PGGRIREKLS RAKSAKVSGA TRHPQPKGHG
1610 1620 1630 1640 1650
SRETPRCPAQ PSVAASQEAG NGYDSEDCEG LLGTEAPPRE AGLLLHTGAS
1660 1670 1680 1690 1700
VAVLGPSPSS VVKMEANQKA KKKKERQGLL GACRLSSPES EVKIKRRSVK
1710 1720 1730 1740 1750
AKVGTTLERA PGQRPPGALG KKKAKGKAKG SLRAEPGATP SRDALFNPSR
1760 1770 1780 1790 1800
AFACREEGSQ LASERLKRAT RKGTVLQPVL RRKNGALSIT LATRNAKAIL
1810 1820 1830 1840 1850
GKGRKLSKVK HKAGKQGKGR AVSRLLESFA VEEDFEFDDN SSFSEEEEDE
1860 1870 1880 1890 1900
EEEEEDSGPL SAEQSAALAR SCAIHKEDLR DGLPVLIPKE DSLLYAGSVR
1910 1920 1930 1940 1950
TLQPPDIYSI VIEGERGNRQ RIYSLEQLLQ EAVLDVRPQS SRYLPPGTRV
1960 1970 1980 1990 2000
CAYWSQKSRC LYPGNVVRGA SGDEDEDLDS VVVEFDDGDT GHIAVSNVRL
2010 2020 2030 2040 2050
LPPDFKIQCT EPSPALLVSS SCRRTKKVSS EAPPPSEAAT PSLSPKAQDG
2060 2070 2080 2090 2100
PEALKTPGKK SISKDKAGKA ELLTSGAKSP TGASDHFLGR RGSPLLSWSA
2110 2120 2130 2140 2150
VAQTKRKAVA AASKGPGVLQ NLFQLNGSSK KLRAREALFP VHSVATPIFG
2160 2170 2180 2190 2200
NGFRADSFSS LASSYAPFVG GTGPGLPRGA HKLLRAKKAE RVEAEKGGRR
2210 2220 2230 2240 2250
RAGGEFLVKL DHEGVTSPKN KTCKALLMGD KDFSPKLGRP LPSPSYVHPA
2260 2270 2280 2290 2300
LVGKDKKGRA PIPPLPMGLA LRKYAGQAEF PLPYDSDCHS SFSDEDEDGP
2310 2320 2330 2340 2350
GLAAGVPSRF LARLSVSSSS SGSSTSSSSG SVSTSSLCSS DNEDSSYSSD
2360 2370 2380 2390 2400
DEDPALLLQT CLTHPVPTLL AQPEALRSKG SGPHAHAQRC FLSRATVAGT
2410 2420 2430 2440 2450
GAGSGPSSSS KSKLKRKEAL SFSKAKELSR RQRPPSVENR PKISAFLPAR
2460 2470 2480 2490 2500
QLWKWSGNPT QRRGMKGKAR KLFYKAIVRG EETLRVGDCA VFLSAGRPNL
2510 2520 2530 2540 2550
PYIGRIESMW ESWGSNMVVK VKWFYHPEET KLGKRQCDGK NALYQSCHED
2560 2570 2580 2590 2600
ENDVQTISHK CQVVAREQYE QMARSRKCQD RQDLYYLAGT YDPTTGRLVT

ADGVPILC
Length:2,608
Mass (Da):276,932
Last modified:September 2, 2008 - v3
Checksum:i494D61C2AC35B35B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti61 – 120SSRLM…HSHEA → CWRLQGNPAAVLCVSPFITS WLGNNRKWHFSGGRSLPFQP AVTCAGPSPFLGYYSLSQPP in AC110285 (PubMed:16625196).CuratedAdd BLAST60
Sequence conflicti1054P → PVARAHSVAHAGLEFLASND PSTSASQSFGIT in BAA95971 (PubMed:10819331).Curated1
Sequence conflicti1621N → S in BAA95971 (PubMed:10819331).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_061559272A → T.Corresponds to variant rs12952981dbSNPEnsembl.1
Natural variantiVAR_0595891137T → A.1 PublicationCorresponds to variant rs7213444dbSNPEnsembl.1
Natural variantiVAR_0615601403R → Q.Corresponds to variant rs35572189dbSNPEnsembl.1
Natural variantiVAR_0615611647T → A.1 PublicationCorresponds to variant rs12601317dbSNPEnsembl.1
Natural variantiVAR_0615621998V → I.Corresponds to variant rs34680524dbSNPEnsembl.1
Natural variantiVAR_0506852479R → C.Corresponds to variant rs8746dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110285 Genomic DNA. No translation available.
AC139149 Genomic DNA. No translation available.
AADB02019016 Genomic DNA. No translation available.
AB040880 mRNA. Translation: BAA95971.1.
BC033222 mRNA. Translation: AAH33222.1.
RefSeqiNP_001278253.1. NM_001291324.1.
UniGeneiHs.514580.

Genome annotation databases

GeneIDi57597.
KEGGihsa:57597.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110285 Genomic DNA. No translation available.
AC139149 Genomic DNA. No translation available.
AADB02019016 Genomic DNA. No translation available.
AB040880 mRNA. Translation: BAA95971.1.
BC033222 mRNA. Translation: AAH33222.1.
RefSeqiNP_001278253.1. NM_001291324.1.
UniGeneiHs.514580.

3D structure databases

ProteinModelPortaliQ9P281.
SMRiQ9P281.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi121648. 10 interactors.
IntActiQ9P281. 5 interactors.
STRINGi9606.ENSP00000303486.

PTM databases

iPTMnetiQ9P281.
PhosphoSitePlusiQ9P281.

Polymorphism and mutation databases

BioMutaiBAHCC1.
DMDMi205371795.

Proteomic databases

EPDiQ9P281.
MaxQBiQ9P281.
PaxDbiQ9P281.
PeptideAtlasiQ9P281.
PRIDEiQ9P281.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi57597.
KEGGihsa:57597.

Organism-specific databases

CTDi57597.
GeneCardsiBAHCC1.
H-InvDBHIX0014249.
HGNCiHGNC:29279. BAHCC1.
HPAiHPA023386.
neXtProtiNX_Q9P281.
PharmGKBiPA128394719.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IUIU. Eukaryota.
ENOG410ZM6U. LUCA.
HOGENOMiHOG000095172.
HOVERGENiHBG107492.
InParanoidiQ9P281.
PhylomeDBiQ9P281.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000171282-MONOMER.

Miscellaneous databases

ChiTaRSiBAHCC1. human.
GenomeRNAii57597.
PROiQ9P281.

Gene expression databases

CleanExiHS_BAHCC1.

Family and domain databases

InterProiIPR001025. BAH_dom.
[Graphical view]
PfamiPF01426. BAH. 1 hit.
[Graphical view]
SMARTiSM00439. BAH. 1 hit.
[Graphical view]
PROSITEiPS51038. BAH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBAHC1_HUMAN
AccessioniPrimary (citable) accession number: Q9P281
Secondary accession number(s): Q5U629
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: September 2, 2008
Last modified: November 2, 2016
This is version 96 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.