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Q9P275

- UBP36_HUMAN

UniProt

Q9P275 - UBP36_HUMAN

Protein

Ubiquitin carboxyl-terminal hydrolase 36

Gene

USP36

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 121 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4) By similarity.By similarity

    Catalytic activityi

    Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).1 Publication

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei131 – 1311NucleophilePROSITE-ProRule annotation
    Active sitei382 – 3821Proton acceptorPROSITE-ProRule annotation

    GO - Molecular functioni

    1. poly(A) RNA binding Source: UniProtKB
    2. ubiquitin-specific protease activity Source: FlyBase

    GO - Biological processi

    1. protein deubiquitination Source: FlyBase
    2. ubiquitin-dependent protein catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protease, Thiol protease

    Keywords - Biological processi

    Ubl conjugation pathway

    Protein family/group databases

    MEROPSiC19.042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ubiquitin carboxyl-terminal hydrolase 36 (EC:3.4.19.12)
    Alternative name(s):
    Deubiquitinating enzyme 36
    Ubiquitin thioesterase 36
    Ubiquitin-specific-processing protease 36
    Gene namesi
    Name:USP36
    Synonyms:KIAA1453
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:20062. USP36.

    Subcellular locationi

    Nucleusnucleolus 1 Publication

    GO - Cellular componenti

    1. nucleolus Source: HPA
    2. nucleus Source: HPA

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134949090.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 11211121Ubiquitin carboxyl-terminal hydrolase 36PRO_0000080666Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei464 – 4641Phosphoserine1 Publication
    Modified residuei582 – 5821Phosphoserine2 Publications
    Modified residuei667 – 6671Phosphoserine2 Publications
    Modified residuei682 – 6821Phosphoserine1 Publication
    Modified residuei713 – 7131Phosphoserine1 Publication
    Modified residuei742 – 7421Phosphoserine2 Publications
    Modified residuei952 – 9521Phosphoserine2 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ9P275.
    PaxDbiQ9P275.
    PeptideAtlasiQ9P275.
    PRIDEiQ9P275.

    2D gel databases

    SWISS-2DPAGEQ9P275.

    PTM databases

    PhosphoSiteiQ9P275.

    Miscellaneous databases

    PMAP-CutDBQ9P275.

    Expressioni

    Tissue specificityi

    Broadly expressed.1 Publication

    Gene expression databases

    ArrayExpressiQ9P275.
    BgeeiQ9P275.
    CleanExiHS_USP36.
    GenevestigatoriQ9P275.

    Organism-specific databases

    HPAiHPA012082.
    HPA052860.

    Interactioni

    Subunit structurei

    Interacts with PAF1.By similarity

    Protein-protein interaction databases

    BioGridi121651. 26 interactions.
    IntActiQ9P275. 23 interactions.
    MINTiMINT-4728276.
    STRINGi9606.ENSP00000310590.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9P275.
    SMRiQ9P275. Positions 122-420.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini122 – 423302USPAdd
    BLAST

    Sequence similaritiesi

    Belongs to the peptidase C19 family.Curated
    Contains 1 USP domain.Curated

    Phylogenomic databases

    eggNOGiCOG5533.
    HOGENOMiHOG000154759.
    HOVERGENiHBG061810.
    InParanoidiQ9P275.
    KOiK11855.
    OMAiHQDPPWH.
    PhylomeDBiQ9P275.
    TreeFamiTF315281.

    Family and domain databases

    InterProiIPR018200. Pept_C19ubi-hydrolase_C_CS.
    IPR001394. Peptidase_C19_UCH.
    IPR028889. UCH/PAN2.
    [Graphical view]
    PfamiPF00443. UCH. 1 hit.
    [Graphical view]
    PROSITEiPS00972. USP_1. 1 hit.
    PS00973. USP_2. 1 hit.
    PS50235. USP_3. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9P275-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MPIVDKLKEA LKPGRKDSAD DGELGKLLAS SAKKVLLQKI EFEPASKSFS     50
    YQLEALKSKY VLLNPKTEGA SRHKSGDDPP ARRQGSEHTY ESCGDGVPAP 100
    QKVLFPTERL SLRWERVFRV GAGLHNLGNT CFLNATIQCL TYTPPLANYL 150
    LSKEHARSCH QGSFCMLCVM QNHIVQAFAN SGNAIKPVSF IRDLKKIARH 200
    FRFGNQEDAH EFLRYTIDAM QKACLNGCAK LDRQTQATTL VHQIFGGYLR 250
    SRVKCSVCKS VSDTYDPYLD VALEIRQAAN IVRALELFVK ADVLSGENAY 300
    MCAKCKKKVP ASKRFTIHRT SNVLTLSLKR FANFSGGKIT KDVGYPEFLN 350
    IRPYMSQNNG DPVMYGLYAV LVHSGYSCHA GHYYCYVKAS NGQWYQMNDS 400
    LVHSSNVKVV LNQQAYVLFY LRIPGSKKSP EGLISRTGSS SLPGRPSVIP 450
    DHSKKNIGNG IISSPLTGKR QDSGTMKKPH TTEEIGVPIS RNGSTLGLKS 500
    QNGCIPPKLP SGSPSPKLSQ TPTHMPTILD DPGKKVKKPA PPQHFSPRTA 550
    QGLPGTSNSN SSRSGSQRQG SWDSRDVVLS TSPKLLATAT ANGHGLKGND 600
    ESAGLDRRGS SSSSPEHSAS SDSTKAPQTP RSGAAHLCDS QETNCSTAGH 650
    SKTPPSGADS KTVKLKSPVL SNTTTEPAST MSPPPAKKLA LSAKKASTLW 700
    RATGNDLRPP PPSPSSDLTH PMKTSHPVVA STWPVHRARA VSPAPQSSSR 750
    LQPPFSPHPT LLSSTPKPPG TSEPRSCSSI STALPQVNED LVSLPHQLPE 800
    ASEPPQSPSE KRKKTFVGEP QRLGSETRLP QHIREATAAP HGKRKRKKKK 850
    RPEDTAASAL QEGQTQRQPG SPMYRREGQA QLPAVRRQED GTQPQVNGQQ 900
    VGCVTDGHHA SSRKRRRKGA EGLGEEGGLH QDPLRHSCSP MGDGDPEAME 950
    ESPRKKKKRK QETQRAVEED GHLKCPRSAK PQDAVVPESS SCAPSANGWC 1000
    PGDRMGLSQA PPVSWNGERE SDVVQELLKY SSDKAYGRKV LTWDGKMSAV 1050
    SQDAIEDSRQ ARTETVVDDW DEEFDRGKEK KIKKFKREKR RNFNAFQKLQ 1100
    TRRNFWSVTH PAKAASLSYR R 1121
    Length:1,121
    Mass (Da):122,652
    Last modified:January 23, 2007 - v3
    Checksum:i23E11A75B20304B7
    GO
    Isoform 2 (identifier: Q9P275-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         958-958: K → KKK

    Show »
    Length:1,123
    Mass (Da):122,908
    Checksum:i65CD93C1B8655319
    GO

    Sequence cautioni

    The sequence AAH16487.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
    The sequence BAA95977.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti82 – 821R → G in AAH71582. (PubMed:15489334)Curated
    Sequence conflicti573 – 5731D → G in BAA91825. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti271 – 2711V → I.1 Publication
    Corresponds to variant rs3744793 [ dbSNP | Ensembl ].
    VAR_037277
    Natural varianti489 – 4891I → M.
    Corresponds to variant rs3744795 [ dbSNP | Ensembl ].
    VAR_037278
    Natural varianti775 – 7751R → Q.
    Corresponds to variant rs9889908 [ dbSNP | Ensembl ].
    VAR_037279
    Natural varianti806 – 8061Q → R.3 Publications
    Corresponds to variant rs3088040 [ dbSNP | Ensembl ].
    VAR_037280
    Natural varianti814 – 8141K → N.
    Corresponds to variant rs3744797 [ dbSNP | Ensembl ].
    VAR_037281
    Natural varianti828 – 8281R → C.2 Publications
    Corresponds to variant rs1057040 [ dbSNP | Ensembl ].
    VAR_037282
    Natural varianti887 – 8871R → P.1 Publication
    Corresponds to variant rs61760231 [ dbSNP | Ensembl ].
    VAR_058034

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei958 – 9581K → KKK in isoform 2. 2 PublicationsVSP_024382

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB040886 mRNA. Translation: BAA95977.1. Different initiation.
    BC016487 mRNA. Translation: AAH16487.1. Sequence problems.
    BC027992 mRNA. Translation: AAH27992.1.
    BC071582 mRNA. Translation: AAH71582.1.
    AK001671 mRNA. Translation: BAA91825.1.
    AL833835 mRNA. Translation: CAD38695.1.
    CCDSiCCDS32755.1. [Q9P275-2]
    RefSeqiNP_079366.3. NM_025090.3. [Q9P275-2]
    UniGeneiHs.464243.

    Genome annotation databases

    EnsembliENST00000312010; ENSP00000310590; ENSG00000055483. [Q9P275-2]
    ENST00000542802; ENSP00000441214; ENSG00000055483. [Q9P275-2]
    ENST00000589225; ENSP00000467280; ENSG00000055483. [Q9P275-2]
    GeneIDi57602.
    KEGGihsa:57602.
    UCSCiuc002jvz.1. human. [Q9P275-2]
    uc002jwc.1. human. [Q9P275-1]

    Polymorphism databases

    DMDMi124056592.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB040886 mRNA. Translation: BAA95977.1 . Different initiation.
    BC016487 mRNA. Translation: AAH16487.1 . Sequence problems.
    BC027992 mRNA. Translation: AAH27992.1 .
    BC071582 mRNA. Translation: AAH71582.1 .
    AK001671 mRNA. Translation: BAA91825.1 .
    AL833835 mRNA. Translation: CAD38695.1 .
    CCDSi CCDS32755.1. [Q9P275-2 ]
    RefSeqi NP_079366.3. NM_025090.3. [Q9P275-2 ]
    UniGenei Hs.464243.

    3D structure databases

    ProteinModelPortali Q9P275.
    SMRi Q9P275. Positions 122-420.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 121651. 26 interactions.
    IntActi Q9P275. 23 interactions.
    MINTi MINT-4728276.
    STRINGi 9606.ENSP00000310590.

    Protein family/group databases

    MEROPSi C19.042.

    PTM databases

    PhosphoSitei Q9P275.

    Polymorphism databases

    DMDMi 124056592.

    2D gel databases

    SWISS-2DPAGE Q9P275.

    Proteomic databases

    MaxQBi Q9P275.
    PaxDbi Q9P275.
    PeptideAtlasi Q9P275.
    PRIDEi Q9P275.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000312010 ; ENSP00000310590 ; ENSG00000055483 . [Q9P275-2 ]
    ENST00000542802 ; ENSP00000441214 ; ENSG00000055483 . [Q9P275-2 ]
    ENST00000589225 ; ENSP00000467280 ; ENSG00000055483 . [Q9P275-2 ]
    GeneIDi 57602.
    KEGGi hsa:57602.
    UCSCi uc002jvz.1. human. [Q9P275-2 ]
    uc002jwc.1. human. [Q9P275-1 ]

    Organism-specific databases

    CTDi 57602.
    GeneCardsi GC17M076792.
    H-InvDB HIX0014226.
    HGNCi HGNC:20062. USP36.
    HPAi HPA012082.
    HPA052860.
    MIMi 612543. gene.
    neXtProti NX_Q9P275.
    PharmGKBi PA134949090.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5533.
    HOGENOMi HOG000154759.
    HOVERGENi HBG061810.
    InParanoidi Q9P275.
    KOi K11855.
    OMAi HQDPPWH.
    PhylomeDBi Q9P275.
    TreeFami TF315281.

    Miscellaneous databases

    GeneWikii USP36.
    GenomeRNAii 57602.
    NextBioi 64221.
    PMAP-CutDB Q9P275.
    PROi Q9P275.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9P275.
    Bgeei Q9P275.
    CleanExi HS_USP36.
    Genevestigatori Q9P275.

    Family and domain databases

    InterProi IPR018200. Pept_C19ubi-hydrolase_C_CS.
    IPR001394. Peptidase_C19_UCH.
    IPR028889. UCH/PAN2.
    [Graphical view ]
    Pfami PF00443. UCH. 1 hit.
    [Graphical view ]
    PROSITEi PS00972. USP_1. 1 hit.
    PS00973. USP_2. 1 hit.
    PS50235. USP_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
      DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS ARG-806 AND CYS-828.
      Tissue: Brain.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANTS ILE-271; ARG-806 AND PRO-887.
      Tissue: Cervix, Placenta and Skin.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-954 (ISOFORM 1), VARIANTS ARG-806 AND CYS-828.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 494-1121 (ISOFORM 2).
      Tissue: Testis.
    5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    6. "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases."
      Quesada V., Diaz-Perales A., Gutierrez-Fernandez A., Garabaya C., Cal S., Lopez-Otin C.
      Biochem. Biophys. Res. Commun. 314:54-62(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY, ENZYME ACTIVITY.
    7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-952, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    8. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-464; SER-582 AND SER-667, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-667 AND SER-682, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-582; SER-713; SER-742 AND SER-952, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-742, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiUBP36_HUMAN
    AccessioniPrimary (citable) accession number: Q9P275
    Secondary accession number(s): Q05C98
    , Q05DD0, Q6IQ38, Q8NDM8, Q9NVC8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2003
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 121 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 17
      Human chromosome 17: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. Peptidase families
      Classification of peptidase families and list of entries
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3