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Q9P241

- AT10D_HUMAN

UniProt

Q9P241 - AT10D_HUMAN

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Protein

Probable phospholipid-transporting ATPase VD

Gene
ATP10D, ATPVD, KIAA1487
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules Inferred.

Catalytic activityi

ATP + H2O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei438 – 43814-aspartylphosphate intermediate By similarity
Metal bindingi1056 – 10561Magnesium By similarity
Metal bindingi1060 – 10601Magnesium By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi996 – 10038ATP Reviewed prediction
Nucleotide bindingi1364 – 13718ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB
  2. cation-transporting ATPase activity Source: InterPro
  3. magnesium ion binding Source: UniProtKB
  4. phospholipid-translocating ATPase activity Source: UniProtKB
  5. protein binding Source: UniProtKB

GO - Biological processi

  1. cation transport Source: UniProtKB
  2. ion transmembrane transport Source: Reactome
  3. phospholipid translocation Source: UniProtKB
  4. transmembrane transport Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid transport, Transport

Keywords - Ligandi

ATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_25149. Ion transport by P-type ATPases.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable phospholipid-transporting ATPase VD (EC:3.6.3.1)
Alternative name(s):
ATPase class V type 10D
P4-ATPase flippase complex alpha subunit ATP10D
Gene namesi
Name:ATP10D
Synonyms:ATPVD, KIAA1487
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 4

Organism-specific databases

HGNCiHGNC:13549. ATP10D.

Subcellular locationi

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane
Note: Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not that of TMEM30B.1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 9797Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei98 – 11821Helical; Reviewed predictionAdd
BLAST
Topological domaini119 – 1213Exoplasmic loop Reviewed prediction
Transmembranei122 – 14221Helical; Reviewed predictionAdd
BLAST
Topological domaini143 – 321179Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei322 – 34221Helical; Reviewed predictionAdd
BLAST
Topological domaini343 – 36523Exoplasmic loop Reviewed predictionAdd
BLAST
Transmembranei366 – 38621Helical; Reviewed predictionAdd
BLAST
Topological domaini387 – 1113727Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei1114 – 113421Helical; Reviewed predictionAdd
BLAST
Topological domaini1135 – 114511Exoplasmic loop Reviewed predictionAdd
BLAST
Transmembranei1146 – 116621Helical; Reviewed predictionAdd
BLAST
Topological domaini1167 – 119529Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei1196 – 121621Helical; Reviewed predictionAdd
BLAST
Topological domaini1217 – 12248Exoplasmic loop Reviewed prediction
Transmembranei1225 – 124521Helical; Reviewed predictionAdd
BLAST
Topological domaini1246 – 12527Cytoplasmic Reviewed prediction
Transmembranei1253 – 127321Helical; Reviewed predictionAdd
BLAST
Topological domaini1274 – 129219Exoplasmic loop Reviewed predictionAdd
BLAST
Transmembranei1293 – 131321Helical; Reviewed predictionAdd
BLAST
Topological domaini1314 – 1426113Cytoplasmic Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB
  2. endoplasmic reticulum membrane Source: UniProtKB-SubCell
  3. integral component of membrane Source: UniProtKB
  4. nucleus Source: HPA
  5. plasma membrane Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endoplasmic reticulum, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25100.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14261426Probable phospholipid-transporting ATPase VDPRO_0000046382Add
BLAST

Proteomic databases

PaxDbiQ9P241.
PRIDEiQ9P241.

PTM databases

PhosphoSiteiQ9P241.

Expressioni

Tissue specificityi

Expressed in placenta and, to a lesser extent, in kidney.1 Publication

Gene expression databases

ArrayExpressiQ9P241.
BgeeiQ9P241.
CleanExiHS_ATP10D.
GenevestigatoriQ9P241.

Organism-specific databases

HPAiHPA050808.

Interactioni

Subunit structurei

Component of a P4-ATPase flippase complex which consists of a catalytic alpha subunit and an accessory beta subunit Inferred.

Protein-protein interaction databases

BioGridi121446. 1 interaction.
STRINGi9606.ENSP00000273859.

Structurei

3D structure databases

ProteinModelPortaliQ9P241.
SMRiQ9P241. Positions 1035-1091.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0474.
HOGENOMiHOG000202528.
HOVERGENiHBG107129.
InParanoidiQ9P241.
KOiK01530.
OMAiMDSTVQC.
OrthoDBiEOG76471S.
PhylomeDBiQ9P241.
TreeFamiTF354252.

Family and domain databases

Gene3Di2.70.150.10. 2 hits.
3.40.1110.10. 3 hits.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR006539. ATPase_P-typ_Plipid-transp.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view]
PANTHERiPTHR24092. PTHR24092. 1 hit.
PfamiPF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSiPR00119. CATATPASE.
SUPFAMiSSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01652. ATPase-Plipid. 2 hits.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9P241-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MTEALQWARY HWRRLIRGAT RDDDSGPYNY SSLLACGRKS SQTPKLSGRH     50
RIVVPHIQPF KDEYEKFSGA YVNNRIRTTK YTLLNFVPRN LFEQFHRAAN 100
LYFLFLVVLN WVPLVEAFQK EITMLPLVVV LTIIAIKDGL EDYRKYKIDK 150
QINNLITKVY SRKEKKYIDR CWKDVTVGDF IRLSCNEVIP ADMVLLFSTD 200
PDGICHIETS GLDGESNLKQ RQVVRGYAEQ DSEVDPEKFS SRIECESPNN 250
DLSRFRGFLE HSNKERVGLS KENLLLRGCT IRNTEAVVGI VVYAGHETKA 300
MLNNSGPRYK RSKLERRANT DVLWCVMLLV IMCLTGAVGH GIWLSRYEKM 350
HFFNVPEPDG HIISPLLAGF YMFWTMIILL QVLIPISLYV SIEIVKLGQI 400
YFIQSDVDFY NEKMDSIVQC RALNIAEDLG QIQYLFSDKT GTLTENKMVF 450
RRCSVAGFDY CHEENARRLE SYQEAVSEDE DFIDTVSGSL SNMAKPRAPS 500
CRTVHNGPLG NKPSNHLAGS SFTLGSGEGA SEVPHSRQAA FSSPIETDVV 550
PDTRLLDKFS QITPRLFMPL DETIQNPPME TLYIIDFFIA LAICNTVVVS 600
APNQPRQKIR HPSLGGLPIK SLEEIKSLFQ RWSVRRSSSP SLNSGKEPSS 650
GVPNAFVSRL PLFSRMKPAS PVEEEVSQVC ESPQCSSSSA CCTETEKQHG 700
DAGLLNGKAE SLPGQPLACN LCYEAESPDE AALVYAARAY QCTLRSRTPE 750
QVMVDFAALG PLTFQLLHIL PFDSVRKRMS VVVRHPLSNQ VVVYTKGADS 800
VIMELLSVAS PDGASLEKQQ MIVREKTQKH LDDYAKQGLR TLCIAKKVMS 850
DTEYAEWLRN HFLAETSIDN REELLLESAM RLENKLTLLG ATGIEDRLQE 900
GVPESIEALH KAGIKIWMLT GDKQETAVNI AYACKLLEPD DKLFILNTQS 950
KDACGMLMST ILKELQKKTQ ALPEQVSLSE DLLQPPVPRD SGLRAGLIIT 1000
GKTLEFALQE SLQKQFLELT SWCQAVVCCR ATPLQKSEVV KLVRSHLQVM 1050
TLAIGDGAND VSMIQVADIG IGVSGQEGMQ AVMASDFAVS QFKHLSKLLL 1100
VHGHWCYTRL SNMILYFFYK NVAYVNLLFW YQFFCGFSGT SMTDYWVLIF 1150
FNLLFTSAPP VIYGVLEKDV SAETLMQLPE LYRSGQKSEA YLPHTFWITL 1200
LDAFYQSLVC FFVPYFTYQG SDTDIFAFGN PLNTAALFIV LLHLVIESKS 1250
LTWIHLLVII GSILSYFLFA IVFGAMCVTC NPPSNPYWIM QEHMLDPVFY 1300
LVCILTTSIA LLPRFVYRVL QGSLFPSPIL RAKHFDRLTP EERTKALKKW 1350
RGAGKMNQVT SKYANQSAGK SGRRPMPGPS AVFAMKSASS CAIEQGNLSL 1400
CETALDQGYS ETKAFEMAGP SKGKES 1426
Length:1,426
Mass (Da):160,274
Last modified:July 13, 2010 - v3
Checksum:i97EE929F81AC59AE
GO
Isoform 2 (identifier: Q9P241-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     553-747: Missing.

Note: No experimental confirmation available.

Show »
Length:1,231
Mass (Da):138,890
Checksum:i67D834DFFCEA7A54
GO

Sequence cautioni

The sequence BAB55221.1 differs from that shown. Reason: Frameshift at position 748.
The sequence BAC11299.1 differs from that shown. Reason: Erroneous initiation.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti43 – 431T → I.1 Publication
Corresponds to variant rs33995001 [ dbSNP | Ensembl ].
VAR_048385
Natural varianti171 – 1711C → R.
Corresponds to variant rs7683838 [ dbSNP | Ensembl ].
VAR_048386
Natural varianti320 – 3201T → I.
Corresponds to variant rs35596623 [ dbSNP | Ensembl ].
VAR_048387
Natural varianti337 – 3371A → T.
Corresponds to variant rs35012290 [ dbSNP | Ensembl ].
VAR_048388
Natural varianti511 – 5111N → S.
Corresponds to variant rs10003238 [ dbSNP | Ensembl ].
VAR_048389
Natural varianti522 – 5221F → L.
Corresponds to variant rs6843325 [ dbSNP | Ensembl ].
VAR_048390
Natural varianti716 – 7161P → T.
Corresponds to variant rs34208443 [ dbSNP | Ensembl ].
VAR_048391
Natural varianti720 – 7201N → S.
Corresponds to variant rs34169638 [ dbSNP | Ensembl ].
VAR_048392
Natural varianti959 – 9591S → N.
Corresponds to variant rs17462252 [ dbSNP | Ensembl ].
VAR_048393
Natural varianti1183 – 11831R → K.
Corresponds to variant rs16851681 [ dbSNP | Ensembl ].
VAR_048394
Natural varianti1240 – 12401V → I.1 Publication
Corresponds to variant rs1058793 [ dbSNP | Ensembl ].
VAR_020187
Natural varianti1389 – 13891S → T.1 Publication
Corresponds to variant rs4145944 [ dbSNP | Ensembl ].
VAR_024371
Natural varianti1392 – 13921A → G.
Corresponds to variant rs35375547 [ dbSNP | Ensembl ].
VAR_048395

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei553 – 747195Missing in isoform 2. VSP_006954Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti142 – 1421D → G in CAD29577. 1 Publication
Sequence conflicti1002 – 10021K → R in CAD29577. 1 Publication
Sequence conflicti1090 – 10901S → Y in CAD29577. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ441078 mRNA. Translation: CAD29577.1.
AC092597 Genomic DNA. No translation available.
AC107398 Genomic DNA. No translation available.
CH471069 Genomic DNA. Translation: EAW93036.1.
BC131535 mRNA. Translation: AAI31536.1.
AK027598 mRNA. Translation: BAB55221.1. Frameshift.
AK074930 mRNA. Translation: BAC11299.1. Different initiation.
AB040920 mRNA. Translation: BAA96011.1.
CCDSiCCDS3476.1. [Q9P241-1]
RefSeqiNP_065186.3. NM_020453.3. [Q9P241-1]
XP_005248175.1. XM_005248118.2. [Q9P241-1]
UniGeneiHs.437241.

Genome annotation databases

EnsembliENST00000273859; ENSP00000273859; ENSG00000145246. [Q9P241-1]
GeneIDi57205.
KEGGihsa:57205.
UCSCiuc003gxk.1. human. [Q9P241-1]
uc003gxl.1. human. [Q9P241-2]

Polymorphism databases

DMDMi300669610.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ441078 mRNA. Translation: CAD29577.1 .
AC092597 Genomic DNA. No translation available.
AC107398 Genomic DNA. No translation available.
CH471069 Genomic DNA. Translation: EAW93036.1 .
BC131535 mRNA. Translation: AAI31536.1 .
AK027598 mRNA. Translation: BAB55221.1 . Frameshift.
AK074930 mRNA. Translation: BAC11299.1 . Different initiation.
AB040920 mRNA. Translation: BAA96011.1 .
CCDSi CCDS3476.1. [Q9P241-1 ]
RefSeqi NP_065186.3. NM_020453.3. [Q9P241-1 ]
XP_005248175.1. XM_005248118.2. [Q9P241-1 ]
UniGenei Hs.437241.

3D structure databases

ProteinModelPortali Q9P241.
SMRi Q9P241. Positions 1035-1091.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121446. 1 interaction.
STRINGi 9606.ENSP00000273859.

PTM databases

PhosphoSitei Q9P241.

Polymorphism databases

DMDMi 300669610.

Proteomic databases

PaxDbi Q9P241.
PRIDEi Q9P241.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000273859 ; ENSP00000273859 ; ENSG00000145246 . [Q9P241-1 ]
GeneIDi 57205.
KEGGi hsa:57205.
UCSCi uc003gxk.1. human. [Q9P241-1 ]
uc003gxl.1. human. [Q9P241-2 ]

Organism-specific databases

CTDi 57205.
GeneCardsi GC04P047487.
HGNCi HGNC:13549. ATP10D.
HPAi HPA050808.
neXtProti NX_Q9P241.
PharmGKBi PA25100.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0474.
HOGENOMi HOG000202528.
HOVERGENi HBG107129.
InParanoidi Q9P241.
KOi K01530.
OMAi MDSTVQC.
OrthoDBi EOG76471S.
PhylomeDBi Q9P241.
TreeFami TF354252.

Enzyme and pathway databases

Reactomei REACT_25149. Ion transport by P-type ATPases.

Miscellaneous databases

GenomeRNAii 57205.
NextBioi 63294.
PROi Q9P241.

Gene expression databases

ArrayExpressi Q9P241.
Bgeei Q9P241.
CleanExi HS_ATP10D.
Genevestigatori Q9P241.

Family and domain databases

Gene3Di 2.70.150.10. 2 hits.
3.40.1110.10. 3 hits.
3.40.50.1000. 2 hits.
InterProi IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR006539. ATPase_P-typ_Plipid-transp.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
[Graphical view ]
PANTHERi PTHR24092. PTHR24092. 1 hit.
Pfami PF00122. E1-E2_ATPase. 1 hit.
[Graphical view ]
PRINTSi PR00119. CATATPASE.
SUPFAMi SSF56784. SSF56784. 2 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsi TIGR01652. ATPase-Plipid. 2 hits.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEi PS00154. ATPASE_E1_E2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of a putative type IV aminophospholipid transporter P-type ATPase."
    Flamant S., Pescher P., Lemercier B., Clement-Ziza M., Kepes F., Fellous M., Milon G., Marchal G., Besmond C.
    Mamm. Genome 14:21-30(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
    Tissue: Monocyte.
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS ILE-43 AND ILE-1240.
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 354-1426 (ISOFORM 2).
  6. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
    Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
    DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 777-1426, VARIANT THR-1389.
    Tissue: Brain.
  7. "ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner."
    Takatsu H., Baba K., Shima T., Umino H., Kato U., Umeda M., Nakayama K., Shin H.W.
    J. Biol. Chem. 286:38159-38167(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.

Entry informationi

Entry nameiAT10D_HUMAN
AccessioniPrimary (citable) accession number: Q9P241
Secondary accession number(s): A2RRC8
, D6REN2, Q8NC70, Q96SR3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: July 13, 2010
Last modified: September 3, 2014
This is version 128 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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