Q9P241 (AT10D_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable phospholipid-transporting ATPase VD
EC=3.6.3.1

Alternative name(s):
ATPase class V type 10D

Gene names

Name:	ATP10D
Synonyms:	ATPVD, KIAA1487

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1426 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + H2O + phospholipid(side 1) = ADP + phosphate + phospholipid(side 2).
Subcellular location	Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Note: Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not that of TMEM30B. Ref.7
Tissue specificity	Expressed in placenta and, to a lesser extent, in kidney. Ref.1
Sequence similarities	Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification]
Sequence caution	The sequence BAB55221.1 differs from that shown. Reason: Frameshift at position 748. The sequence BAC11299.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cell membrane Endoplasmic reticulum Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Magnesium Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cation transport Non-traceable author statement Ref.1. Source: UniProtKB ion transmembrane transport Traceable author statement. Source: Reactome phospholipid translocation Non-traceable author statement Ref.7. Source: UniProtKB
Cellular_component	endoplasmic reticulum Inferred from direct assay Ref.7. Source: UniProtKB endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Non-traceable author statement Ref.1. Source: UniProtKB plasma membrane Traceable author statement. Source: Reactome
Molecular_function	ATP binding Non-traceable author statement Ref.1. Source: UniProtKB cation-transporting ATPase activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Non-traceable author statement Ref.1. Source: UniProtKB phospholipid-translocating ATPase activity Non-traceable author statement Ref.1. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9P241-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9P241-2)

The sequence of this isoform differs from the canonical sequence as follows:
     553-747: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1426	1426	Probable phospholipid-transporting ATPase VD		PRO_0000046382
Regions
	Topological domain	1 – 97	97	Cytoplasmic Potential
	Transmembrane	98 – 118	21	Helical; Potential
	Topological domain	119 – 121	3	Extracellular Potential
	Transmembrane	122 – 142	21	Helical; Potential
	Topological domain	143 – 321	179	Cytoplasmic Potential
	Transmembrane	322 – 342	21	Helical; Potential
	Topological domain	343 – 365	23	Extracellular Potential
	Transmembrane	366 – 386	21	Helical; Potential
	Topological domain	387 – 1113	727	Cytoplasmic Potential
	Transmembrane	1114 – 1134	21	Helical; Potential
	Topological domain	1135 – 1145	11	Extracellular Potential
	Transmembrane	1146 – 1166	21	Helical; Potential
	Topological domain	1167 – 1195	29	Cytoplasmic Potential
	Transmembrane	1196 – 1216	21	Helical; Potential
	Topological domain	1217 – 1224	8	Extracellular Potential
	Transmembrane	1225 – 1245	21	Helical; Potential
	Topological domain	1246 – 1252	7	Cytoplasmic Potential
	Transmembrane	1253 – 1273	21	Helical; Potential
	Topological domain	1274 – 1292	19	Extracellular Potential
	Transmembrane	1293 – 1313	21	Helical; Potential
	Topological domain	1314 – 1426	113	Cytoplasmic Potential
	Nucleotide binding	996 – 1003	8	ATP Potential
	Nucleotide binding	1364 – 1371	8	ATP Potential
Sites
	Active site	438	1	4-aspartylphosphate intermediate By similarity
	Metal binding	1056	1	Magnesium By similarity
	Metal binding	1060	1	Magnesium By similarity
Natural variations
	Alternative sequence	553 – 747	195	Missing in isoform 2.		VSP_006954
	Natural variant	43	1	T → I. Ref.4 Corresponds to variant rs33995001 [ dbSNP | Ensembl ].		VAR_048385
	Natural variant	171	1	C → R. Corresponds to variant rs7683838 [ dbSNP | Ensembl ].		VAR_048386
	Natural variant	320	1	T → I. Corresponds to variant rs35596623 [ dbSNP | Ensembl ].		VAR_048387
	Natural variant	337	1	A → T. Corresponds to variant rs35012290 [ dbSNP | Ensembl ].		VAR_048388
	Natural variant	511	1	N → S. Corresponds to variant rs10003238 [ dbSNP | Ensembl ].		VAR_048389
	Natural variant	522	1	F → L. Corresponds to variant rs6843325 [ dbSNP | Ensembl ].		VAR_048390
	Natural variant	716	1	P → T. Corresponds to variant rs34208443 [ dbSNP | Ensembl ].		VAR_048391
	Natural variant	720	1	N → S. Corresponds to variant rs34169638 [ dbSNP | Ensembl ].		VAR_048392
	Natural variant	959	1	S → N. Corresponds to variant rs17462252 [ dbSNP | Ensembl ].		VAR_048393
	Natural variant	1183	1	R → K. Corresponds to variant rs16851681 [ dbSNP | Ensembl ].		VAR_048394
	Natural variant	1240	1	V → I. Ref.4 Corresponds to variant rs1058793 [ dbSNP | Ensembl ].		VAR_020187
	Natural variant	1389	1	S → T. Ref.6 Corresponds to variant rs4145944 [ dbSNP | Ensembl ].		VAR_024371
	Natural variant	1392	1	A → G. Corresponds to variant rs35375547 [ dbSNP | Ensembl ].		VAR_048395
Experimental info
	Sequence conflict	142	1	D → G in CAD29577. Ref.1
	Sequence conflict	1002	1	K → R in CAD29577. Ref.1
	Sequence conflict	1090	1	S → Y in CAD29577. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified July 13, 2010. Version 3. Checksum: 97EE929F81AC59AE	FASTA	1,426	160,274
	10 20 30 40 50 60 MTEALQWARY HWRRLIRGAT RDDDSGPYNY SSLLACGRKS SQTPKLSGRH RIVVPHIQPF 70 80 90 100 110 120 KDEYEKFSGA YVNNRIRTTK YTLLNFVPRN LFEQFHRAAN LYFLFLVVLN WVPLVEAFQK 130 140 150 160 170 180 EITMLPLVVV LTIIAIKDGL EDYRKYKIDK QINNLITKVY SRKEKKYIDR CWKDVTVGDF 190 200 210 220 230 240 IRLSCNEVIP ADMVLLFSTD PDGICHIETS GLDGESNLKQ RQVVRGYAEQ DSEVDPEKFS 250 260 270 280 290 300 SRIECESPNN DLSRFRGFLE HSNKERVGLS KENLLLRGCT IRNTEAVVGI VVYAGHETKA 310 320 330 340 350 360 MLNNSGPRYK RSKLERRANT DVLWCVMLLV IMCLTGAVGH GIWLSRYEKM HFFNVPEPDG 370 380 390 400 410 420 HIISPLLAGF YMFWTMIILL QVLIPISLYV SIEIVKLGQI YFIQSDVDFY NEKMDSIVQC 430 440 450 460 470 480 RALNIAEDLG QIQYLFSDKT GTLTENKMVF RRCSVAGFDY CHEENARRLE SYQEAVSEDE 490 500 510 520 530 540 DFIDTVSGSL SNMAKPRAPS CRTVHNGPLG NKPSNHLAGS SFTLGSGEGA SEVPHSRQAA 550 560 570 580 590 600 FSSPIETDVV PDTRLLDKFS QITPRLFMPL DETIQNPPME TLYIIDFFIA LAICNTVVVS 610 620 630 640 650 660 APNQPRQKIR HPSLGGLPIK SLEEIKSLFQ RWSVRRSSSP SLNSGKEPSS GVPNAFVSRL 670 680 690 700 710 720 PLFSRMKPAS PVEEEVSQVC ESPQCSSSSA CCTETEKQHG DAGLLNGKAE SLPGQPLACN 730 740 750 760 770 780 LCYEAESPDE AALVYAARAY QCTLRSRTPE QVMVDFAALG PLTFQLLHIL PFDSVRKRMS 790 800 810 820 830 840 VVVRHPLSNQ VVVYTKGADS VIMELLSVAS PDGASLEKQQ MIVREKTQKH LDDYAKQGLR 850 860 870 880 890 900 TLCIAKKVMS DTEYAEWLRN HFLAETSIDN REELLLESAM RLENKLTLLG ATGIEDRLQE 910 920 930 940 950 960 GVPESIEALH KAGIKIWMLT GDKQETAVNI AYACKLLEPD DKLFILNTQS KDACGMLMST 970 980 990 1000 1010 1020 ILKELQKKTQ ALPEQVSLSE DLLQPPVPRD SGLRAGLIIT GKTLEFALQE SLQKQFLELT 1030 1040 1050 1060 1070 1080 SWCQAVVCCR ATPLQKSEVV KLVRSHLQVM TLAIGDGAND VSMIQVADIG IGVSGQEGMQ 1090 1100 1110 1120 1130 1140 AVMASDFAVS QFKHLSKLLL VHGHWCYTRL SNMILYFFYK NVAYVNLLFW YQFFCGFSGT 1150 1160 1170 1180 1190 1200 SMTDYWVLIF FNLLFTSAPP VIYGVLEKDV SAETLMQLPE LYRSGQKSEA YLPHTFWITL 1210 1220 1230 1240 1250 1260 LDAFYQSLVC FFVPYFTYQG SDTDIFAFGN PLNTAALFIV LLHLVIESKS LTWIHLLVII 1270 1280 1290 1300 1310 1320 GSILSYFLFA IVFGAMCVTC NPPSNPYWIM QEHMLDPVFY LVCILTTSIA LLPRFVYRVL 1330 1340 1350 1360 1370 1380 QGSLFPSPIL RAKHFDRLTP EERTKALKKW RGAGKMNQVT SKYANQSAGK SGRRPMPGPS 1390 1400 1410 1420 AVFAMKSASS CAIEQGNLSL CETALDQGYS ETKAFEMAGP SKGKES
	Isoform 2 [UniParc]. Checksum: 67D834DFFCEA7A54	FASTA	1,231	138,890
	10 20 30 40 50 60 MTEALQWARY HWRRLIRGAT RDDDSGPYNY SSLLACGRKS SQTPKLSGRH RIVVPHIQPF 70 80 90 100 110 120 KDEYEKFSGA YVNNRIRTTK YTLLNFVPRN LFEQFHRAAN LYFLFLVVLN WVPLVEAFQK 130 140 150 160 170 180 EITMLPLVVV LTIIAIKDGL EDYRKYKIDK QINNLITKVY SRKEKKYIDR CWKDVTVGDF 190 200 210 220 230 240 IRLSCNEVIP ADMVLLFSTD PDGICHIETS GLDGESNLKQ RQVVRGYAEQ DSEVDPEKFS 250 260 270 280 290 300 SRIECESPNN DLSRFRGFLE HSNKERVGLS KENLLLRGCT IRNTEAVVGI VVYAGHETKA 310 320 330 340 350 360 MLNNSGPRYK RSKLERRANT DVLWCVMLLV IMCLTGAVGH GIWLSRYEKM HFFNVPEPDG 370 380 390 400 410 420 HIISPLLAGF YMFWTMIILL QVLIPISLYV SIEIVKLGQI YFIQSDVDFY NEKMDSIVQC 430 440 450 460 470 480 RALNIAEDLG QIQYLFSDKT GTLTENKMVF RRCSVAGFDY CHEENARRLE SYQEAVSEDE 490 500 510 520 530 540 DFIDTVSGSL SNMAKPRAPS CRTVHNGPLG NKPSNHLAGS SFTLGSGEGA SEVPHSRQAA 550 560 570 580 590 600 FSSPIETDVV PDTPEQVMVD FAALGPLTFQ LLHILPFDSV RKRMSVVVRH PLSNQVVVYT 610 620 630 640 650 660 KGADSVIMEL LSVASPDGAS LEKQQMIVRE KTQKHLDDYA KQGLRTLCIA KKVMSDTEYA 670 680 690 700 710 720 EWLRNHFLAE TSIDNREELL LESAMRLENK LTLLGATGIE DRLQEGVPES IEALHKAGIK 730 740 750 760 770 780 IWMLTGDKQE TAVNIAYACK LLEPDDKLFI LNTQSKDACG MLMSTILKEL QKKTQALPEQ 790 800 810 820 830 840 VSLSEDLLQP PVPRDSGLRA GLIITGKTLE FALQESLQKQ FLELTSWCQA VVCCRATPLQ 850 860 870 880 890 900 KSEVVKLVRS HLQVMTLAIG DGANDVSMIQ VADIGIGVSG QEGMQAVMAS DFAVSQFKHL 910 920 930 940 950 960 SKLLLVHGHW CYTRLSNMIL YFFYKNVAYV NLLFWYQFFC GFSGTSMTDY WVLIFFNLLF 970 980 990 1000 1010 1020 TSAPPVIYGV LEKDVSAETL MQLPELYRSG QKSEAYLPHT FWITLLDAFY QSLVCFFVPY 1030 1040 1050 1060 1070 1080 FTYQGSDTDI FAFGNPLNTA ALFIVLLHLV IESKSLTWIH LLVIIGSILS YFLFAIVFGA 1090 1100 1110 1120 1130 1140 MCVTCNPPSN PYWIMQEHML DPVFYLVCIL TTSIALLPRF VYRVLQGSLF PSPILRAKHF 1150 1160 1170 1180 1190 1200 DRLTPEERTK ALKKWRGAGK MNQVTSKYAN QSAGKSGRRP MPGPSAVFAM KSASSCAIEQ 1210 1220 1230 GNLSLCETAL DQGYSETKAF EMAGPSKGKE S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Characterization of a putative type IV aminophospholipid transporter P-type ATPase." Flamant S., Pescher P., Lemercier B., Clement-Ziza M., Kepes F., Fellous M., Milon G., Marchal G., Besmond C. Mamm. Genome 14:21-30(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY. Tissue: Monocyte.
[2]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS ILE-43 AND ILE-1240.
[5]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 354-1426 (ISOFORM 2).
[6]	"Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O. DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 777-1426, VARIANT THR-1389. Tissue: Brain.
[7]	"ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner." Takatsu H., Baba K., Shima T., Umino H., Kato U., Umeda M., Nakayama K., Shin H.W. J. Biol. Chem. 286:38159-38167(2011) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ441078 mRNA. Translation: CAD29577.1. AC092597 Genomic DNA. No translation available. AC107398 Genomic DNA. No translation available. CH471069 Genomic DNA. Translation: EAW93036.1. BC131535 mRNA. Translation: AAI31536.1. AK027598 mRNA. Translation: BAB55221.1. Frameshift. AK074930 mRNA. Translation: BAC11299.1. Different initiation. AB040920 mRNA. Translation: BAA96011.1.
IPI	IPI00001723. IPI00216521.
RefSeq	NP_065186.3. NM_020453.3.
UniGene	Hs.437241.
3D structure databases
ProteinModelPortal	Q9P241.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000273859.
PTM databases
PhosphoSite	Q9P241.
Polymorphism databases
DMDM	300669610.
Proteomic databases
PaxDb	Q9P241.
PRIDE	Q9P241.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000273859; ENSP00000273859; ENSG00000145246.
GeneID	57205.
KEGG	hsa:57205.
UCSC	uc003gxk.1. human. uc003gxl.1. human.
Organism-specific databases
CTD	57205.
GeneCards	GC04P047487.
HGNC	HGNC:13549. ATP10D.
HPA	HPA050808.
neXtProt	NX_Q9P241.
PharmGKB	PA25100.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0474.
HOGENOM	HOG000202528.
HOVERGEN	HBG107129.
InParanoid	Q9P241.
KO	K01530.
OMA	AMRLENK.
OrthoDB	EOG45DWNJ.
PhylomeDB	Q9P241.
Enzyme and pathway databases
Reactome	REACT_15518. Transmembrane transport of small molecules.
Gene expression databases
ArrayExpress	Q9P241.
Bgee	Q9P241.
CleanEx	HS_ATP10D.
Genevestigator	Q9P241.
GermOnline	ENSG00000145246. Homo sapiens.
Family and domain databases
Gene3D	2.70.150.10. 2 hits. 3.40.1110.10. 3 hits. 3.40.50.1000. 2 hits.
InterPro	IPR023299. ATPase_P-typ_cyto_domN. IPR018303. ATPase_P-typ_P_site. IPR006539. ATPase_P-typ_Plipid-transp. IPR008250. ATPase_P-typ_transduc_dom_A. IPR001757. Cation_transp_P_typ_ATPase. IPR023214. HAD-like_dom. [Graphical view]
PANTHER	PTHR24092. PTHR24092. 1 hit.
Pfam	PF00122. E1-E2_ATPase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SUPFAM	SSF81660. ATPase_cation_domN. 1 hit. SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01652. ATPase-Plipid. 2 hits. TIGR01494. ATPase_P-type. 2 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	57205.
NextBio	63294.

Entry information

Entry name

AT10D_HUMAN

Accession

Primary (citable) accession number: Q9P241
Secondary accession number(s): A2RRC8 , D6REN2, Q8NC70, Q96SR3

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 18, 2001
Last sequence update:	July 13, 2010
Last modified:	May 1, 2013
This is version 116 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.